日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Optimizing anti-PI3Kδ and anti-LAG-3 immunotherapy dosing regimens in a mouse model of triple-negative breast cancer improves outcome by removing treatment-related adverse events.

在三阴性乳腺癌小鼠模型中优化抗 PI3Kδ 和抗 LAG-3 免疫疗法的给药方案,可消除与治疗相关的不良事件,从而改善治疗效果。

Lauder Sarah Nicol, Pires Ana, Somerville Michelle, Capitani Lorenzo, Smart Kathryn, Geary James, Mills Emily M, Vanhaesebroeck Bart, Godkin Andrew, Gallimore Awen

Valaciclovir therapy for secondary suppression of immune response to herpesviruses: An exploratory study

伐昔洛韦治疗疱疹病毒继发性免疫抑制:一项探索性研究

McGee, Kirsty; Dowell, Alex; Lauder, Sarah; Begum, Jusnara; Chagoury, Odette; Croft, Wayne; Middleton, Lee; Sun, Yongzhong; Zuo, Jianmin; McManus, Richard; Moss, Paul

Lower Humoral and Cellular Immunity Following Asymptomatic SARS-CoV-2 Infection Compared to Symptomatic Infection in Education (The ACE Cohort).

与有症状感染者相比,无症状 SARS-CoV-2 感染者在教育领域(ACE 队列)的体液免疫和细胞免疫较低

Hopkins Georgina, Gomez Nancy, Tucis Davis, Bartlett Laura, Steers Graham, Burns Ellie, Brown Michaela, Harvey-Cowlishaw Tyler, Santos Rute, Lauder Sarah N, Scurr Martin, Capitani Lorenzo, Burnell Stephanie, Rees Tara, Smart Kathryn, Somerville Michelle, Gallimore Awen, Perera Marianne, Potts Martin, Metaxaki Marina, Krishna Benjamin, Jackson Hannah, Tighe Paddy, Onion David, Godkin Andrew, Wills Mark, Fairclough Lucy

Acquisition of suppressive function by conventional T cells limits antitumor immunity upon T(reg) depletion

传统T细胞获得抑制功能后,T(reg)细胞耗竭会限制抗肿瘤免疫力。

Whiteside, Sarah K; Grant, Francis M; Alvisi, Giorgia; Clarke, James; Tang, Leqi; Imianowski, Charlotte J; Zhang, Baojie; Evans, Alexander C; Wesolowski, Alexander J; Conti, Alberto G; Yang, Jie; Lauder, Sarah N; Clement, Mathew; Humphreys, Ian R; Dooley, James; Burton, Oliver; Liston, Adrian; Alloisio, Marco; Voulaz, Emanuele; Langhorne, Jean; Okkenhaug, Klaus; Lugli, Enrico; Roychoudhuri, Rahul

Magnitude of venous or capillary blood-derived SARS-CoV-2-specific T cell response determines COVID-19 immunity

静脉或毛细血管血液中SARS-CoV-2特异性T细胞反应的强度决定了COVID-19的免疫力。

Scurr, Martin J; Lippiatt, George; Capitani, Lorenzo; Bentley, Kirsten; Lauder, Sarah N; Smart, Kathryn; Somerville, Michelle S; Rees, Tara; Stanton, Richard J; Gallimore, Awen; Hindley, James P; Godkin, Andrew

The Ussing chamber system for measuring intestinal permeability in health and disease

Ussing室系统用于测量健康和疾病状态下的肠道通透性

Thomson, Amanda; Smart, Kathryn; Somerville, Michelle S; Lauder, Sarah N; Appanna, Gautham; Horwood, James; Sunder Raj, Lawrence; Srivastava, Brijesh; Durai, Dharmaraj; Scurr, Martin J; Keita, Åsa V; Gallimore, Awen M; Godkin, Andrew

Preferential Generation of 15-HETE-PE Induced by IL-13 Regulates Goblet Cell Differentiation in Human Airway Epithelial Cells

IL-13诱导的15-HETE-PE优先生成调控人呼吸道上皮细胞中杯状细胞的分化

Zhao, Jinming; Minami, Yoshinori; Etling, Emily; Coleman, John M; Lauder, Sarah N; Tyrrell, Victoria; Aldrovandi, Maceler; O'Donnell, Valerie; Claesson, Hans-Erik; Kagan, Valerian; Wenzel, Sally

Cytomegalovirus seropositivity is associated with increased arterial stiffness in patients with chronic kidney disease

巨细胞病毒血清阳性与慢性肾脏病患者的动脉僵硬度增加相关。

Wall, Nadezhda A; Chue, Colin D; Edwards, Nicola C; Pankhurst, Tanya; Harper, Lorraine; Steeds, Richard P; Lauder, Sarah; Townend, Jonathan N; Moss, Paul; Ferro, Charles J

Novel keto-phospholipids are generated by monocytes and macrophages, detected in cystic fibrosis, and activate peroxisome proliferator-activated receptor-γ.

单核细胞和巨噬细胞会产生新型酮磷脂,在囊性纤维化中可以检测到这些新型酮磷脂,并激活过氧化物酶体增殖物激活受体-γ

Hammond Victoria J, Morgan Alwena H, Lauder Sarah, Thomas Christopher P, Brown Sarah, Freeman Bruce A, Lloyd Clare M, Davies Jane, Bush Andrew, Levonen Anna-Liisa, Kansanen Emilia, Villacorta Luis, Chen Y Eugene, Porter Ned, Garcia-Diaz Yoel M, Schopfer Francisco J, O'Donnell Valerie B

Interleukin-6 is crucial for recall of influenza-specific memory CD4 T cells.

白细胞介素-6对于流感特异性记忆CD4 T细胞的重新激活至关重要

Longhi Maria Paula, Wright Kate, Lauder Sarah N, Nowell Mari A, Jones Gareth W, Godkin Andrew J, Jones Simon A, Gallimore Awen M