日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Muscle-specific Ryanodine receptor 1 properties underlie limb-girdle muscular dystrophy 2B/R2 progression.

肌肉特异性的Ryanodine受体1特性是肢带型肌营养不良症2B/R2进展的基础

Meizoso-Huesca Aldo, Lamboley Cedric R, Krycer James R, Hodson Mark P, Hudson James E, Launikonis Bradley S

Evolutionary isolation of ryanodine receptor isoform 1 for muscle-based thermogenesis in mammals

瑞诺丁受体异构体 1 的进化分离,用于哺乳动物肌肉产热

Daniel P Singh, Luke Pearce, Rocky H Choi, Aldo Meizoso-Huesca, Stefan G Wette, John W Scott, Cedric R Lamboley, Robyn M Murphy, Bradley S Launikonis

Cardiac ryanodine receptor N-terminal region biosensors identify novel inhibitors via FRET-based high-throughput screening

心脏瑞诺丁受体 N 端区域生物传感器通过基于 FRET 的高通量筛选识别新型抑制剂

Jingyan Zhang, Daniel P Singh, Christopher Y Ko, Roman Nikolaienko, Siobhan M Wong King Yuen, Jacob A Schwarz, Levy M Treinen, Ching-Chieh Tung, Kaja Rožman, Bengt Svensson, Courtney C Aldrich, Aleksey V Zima, David D Thomas, Donald M Bers, Bradley S Launikonis, Filip Van Petegem, Razvan L Cornea

Correction: A mathematical model to quantify RYR Ca2+ leak and associated heat production in resting human skeletal muscle fibers

更正:用于量化静息状态下人体骨骼肌纤维中RYR Ca2+泄漏及其相关产热的数学模型

Barclay, Christopher J; Launikonis, Bradley S

A mathematical model to quantify RYR Ca2+ leak and associated heat production in resting human skeletal muscle fibers

建立数学模型以量化静息状态下人体骨骼肌纤维中RYR Ca2+泄漏及其相关产热。

Barclay, Christopher J; Launikonis, Bradley S

Ryanodine receptor leak triggers fiber Ca2+ redistribution to preserve force and elevate basal metabolism in skeletal muscle

瑞安诺丁受体泄漏触发纤维 Ca2+ 重新分布以保持力量并提高骨骼肌的基础代谢

Cedric R Lamboley, Luke Pearce, Crystal Seng, Aldo Meizoso-Huesca, Daniel P Singh, Barnaby P Frankish, Vikas Kaura, Harriet P Lo, Charles Ferguson, Paul D Allen, Philip M Hopkins, Robert G Parton, Robyn M Murphy, Chris van der Poel, Christopher J Barclay, Bradley S Launikonis

A chloride channel blocker prevents the suppression by inorganic phosphate of the cytosolic calcium signals that control muscle contraction

氯离子通道阻滞剂可防止无机磷酸盐抑制胞质钙信号,从而阻止肌肉收缩。

Ferreira, Juan J; Pequera, Germán; Launikonis, Bradley S; Ríos, Eduardo; Brum, Gustavo

A new selective pharmacological enhancer of the Orai1 Ca(2+) channel reveals roles for Orai1 in smooth and skeletal muscle functions.

Orai1 Ca(2+) 通道的新型选择性药理增强剂揭示了 Orai1 在平滑肌和骨骼肌功能中的作用

Azimi Iman, Stevenson Ralph J, Zhang Xuexin, Meizoso-Huesca Aldo, Xin Ping, Johnson Martin, Flanagan Jack U, Chalmers Silke B, Yoast Ryan E, Kapure Jeevak S, Ross Benjamin P, Vetter Irina, Ashton Mark R, Launikonis Bradley S, Denny William A, Trebak Mohamed, Monteith Gregory R

Junctional membrane Ca(2+) dynamics in human muscle fibers are altered by malignant hyperthermia causative RyR mutation

恶性高热致病基因RyR突变会改变人类肌肉纤维连接膜上的Ca(2+)动态变化。

Cully, Tanya R; Choi, Rocky H; Bjorksten, Andrew R; Stephenson, D George; Murphy, Robyn M; Launikonis, Bradley S

Store-operated Ca(2+) entry is activated by every action potential in skeletal muscle

骨骼肌中每一次动作电位都会激活胞内钙库操纵性钙离子内流。

Koenig, Xaver; Choi, Rocky H; Launikonis, Bradley S