日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

mRNA-based CAR T cell engineering: Unmodified mRNA enables high CAR expression without innate immune activation in T cells

基于mRNA的CAR-T细胞工程:未经修饰的mRNA可在不激活T细胞固有免疫的情况下实现高水平的CAR表达

Kahwaji, Nourhan; Kotzian, Niklas; Prinz, Jasmin Melissa; Pu, Yaolin; Kath, Jonas; Picht, Samira; Hiller, Anna Luisa; Klaas, Antonia; Dunne, Charlotte Maeve; Launspach, Michael; Palmowski, Andriko; Kleyer, Arnd; Simon, David Nils; Wagner, Dimitrios Laurin; Pichon, Chantal; Krönke, Gerhard; Schmueck-Henneresse, Michael; Volk, Hans-Dieter; Gossen, Manfred; Drzeniek, Norman Michael

Personalized CRISPR knock-in cytokine gene therapy to remodel the tumor microenvironment and enhance CAR T cell therapy in solid tumors

利用CRISPR敲入细胞因子基因疗法个性化肿瘤微环境,增强CAR-T细胞疗法在实体瘤中的疗效

Launspach, Michael; Macos, Julia; Afzal, Shoaib; Hohmann, Janik; Appis, Marc L; Pilgram, Maximilian; Beez, Stefanie; Ohlendorf, Emily; van der Ven, Casper F T; Lachiheb, Chahrazad; Töws, Karin; Andersch, Lena; Jens, Marvin; Zirngibl, Felix; Kath, Jonas; Stecklum, Maria; Rodriguez-Fos, Elias; Anders, Kathleen; Wagner, Dimitrios L; Henssen, Anton G; Kühn, Ralf; Eggert, Angelika; Künkele, Annette

High Incidence and Impact of Suspected Exocrine Pancreatic Insufficiency in Patients Post-Hematopoietic Stem Cell Transplantation: A Single-Center Prospective Observational Study

造血干细胞移植后患者疑似外分泌胰腺功能不全的高发生率及其影响:一项单中心前瞻性观察研究

Launspach, Michael; Mindermann, Aurika; Schulz, Joachim; Alasfar, Lina; Cyrull, Sandra; Zirngibl, Felix; Oevermann, Lena; Künkele, Annette; Deubzer, Hedwig E; von Bernuth, Horst; Pruß, Axel; Lang, Peter; Bufler, Philip; Eggert, Angelika; von Stackelberg, Arend; Schulte, Johannes H

Investigating genetic modifications to enhance L1CAM-CAR T cell migration in solid tumors in a 3D bioprinted neuroblastoma model

在3D生物打印神经母细胞瘤模型中,研究基因修饰以增强L1CAM-CAR T细胞在实体瘤中的迁移能力

Andersch, Lena; Grunewald, Laura; Stecklum, Maria; Klironomos, Filippos; Haase, Kerstin; Hollek, Viola; Lam, Tobias; Jung, Beate Anahita; Winkler, Anika; Schwiebert, Silke; Astrahantseff, Kathy; Launspach, Michael; Jens, Marvin; Henssen, Anton; Kloke, Lutz; Blüthgen, Nils; Eggert, Angelika; Schulte, Johannes H; Anders, Kathleen; Künkele, Annette

Rituximab therapy after pediatric hematopoietic stem cell transplantation can cause prolonged B-cell impairment and increases the risk for infections - a retrospective matched cohort study

儿童造血干细胞移植后接受利妥昔单抗治疗可导致B细胞功能长期受损并增加感染风险——一项回顾性匹配队列研究

Launspach, Michael; Temel, Dennis; Ohlendorf, Emily; Zirngibl, Felix; Materne, Bianca; Oevermann, Lena; Deubzer, Hedwig E; Henssen, Anton G; Künkele, Annette; Hundsdörfer, Patrick; Bernuth, Horst von; Pruß, Axel; Eggert, Angelika; Stackelberg, Arend von; Lang, Peter; Schulte, Johannes H

Combination of GD2-directed bispecific trifunctional antibody therapy with Pd-1 immune checkpoint blockade induces anti-neuroblastoma immunity in a syngeneic mouse model

GD2靶向双特异性三功能抗体疗法与PD-1免疫检查点阻断疗法联合应用,可在同源小鼠模型中诱导抗神经母细胞瘤免疫。

Sara Marie Ivasko ,Kathleen Anders ,Laura Grunewald ,Michael Launspach ,Anika Klaus ,Silke Schwiebert ,Peter Ruf ,Horst Lindhofer ,Holger N Lode ,Lena Andersch ,Johannes H Schulte ,Angelika Eggert ,Patrick Hundsdoerfer ,Annette Künkele ,Felix Zirngibl

The Effect of Branched Alkyl Chain Length on the Properties of Supramolecular Organogels from Mono-N-Alkylated Primary Oxalamides

支链烷基链长度对单烷基化伯草酰胺超分子有机凝胶性能的影响

Azyat, Khalid; Makeiff, Darren; Smith, Bradley; Wiebe, Mickie; Launspach, Steve; Wagner, Ashley; Kulka, Marianna; Godbert, Nicolas

Human well-being and natural capital indictors for Great Lakes waterfront revitalization

五大湖滨水区振兴的人类福祉和自然资本指标

Angradi, Ted R; Launspach, Jonathon J; Wick, Molly J

Amphotericin B induces epithelial voltage responses in people with cystic fibrosis

两性霉素B可诱导囊性纤维化患者上皮细胞产生电压反应

Rajeev S Chorghade ,Bo Ram Kim ,Janice L Launspach ,Philip H Karp ,Michael J Welsh ,Martin D Burke

Clinical Presentation and Management of a Dinutuximab Beta Extravasation in a Patient with Neuroblastoma

神经母细胞瘤患者发生迪努妥昔单抗β外渗的临床表现和处理

Launspach, Michael; Seif, Marita; Thole, Theresa M; Jesse, Patrick; Schulz, Joachim; Schulte, Johannes H; Bischoff, Susan; Eggert, Angelika; Deubzer, Hedwig E