日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Treating Parkinson's Disease via Activation of BDNF/TrkB Signaling Pathways and Inhibition of Delta-Secretase

通过激活 BDNF/TrkB 信号通路和抑制 Delta-Secretase 治疗帕金森病

Seong Su Kang #, Zhourui Wu #, Xia Liu, Laura Edgington-Mitchell, Keqiang Ye

ApoE4 activates C/EBPβ/δ-secretase with 27-hydroxycholesterol, driving the pathogenesis of Alzheimer's disease

ApoE4 通过 27-羟基胆固醇激活 C/EBPβ/δ-分泌酶,从而驱动阿尔茨海默病的发病机制

Zhi-Hao Wang, Yiyuan Xia, Pai Liu, Xia Liu, Laura Edgington-Mitchell, Kecheng Lei, Shan Ping Yu, Xiao-Chuan Wang, Keqiang Ye

PD-1 Inhibitory Receptor Downregulates Asparaginyl Endopeptidase and Maintains Foxp3 Transcription Factor Stability in Induced Regulatory T Cells

PD-1 抑制受体下调天冬酰胺酰内肽酶并维持诱导调节性 T 细胞中的 Foxp3 转录因子稳定性

Chaido Stathopoulou, Arunakumar Gangaplara, Grace Mallett, Francis A Flomerfelt, Lukasz P Liniany, David Knight, Leigh A Samsel, Rolando Berlinguer-Palmini, Joshua J Yim, Tania C Felizardo, Michael A Eckhaus, Laura Edgington-Mitchell, Jonathan Martinez-Fabregas, Jinfang Zhu, Daniel H Fowler, Sander

Cathepsin B inhibition limits bone metastasis in breast cancer

抑制组织蛋白酶B可限制乳腺癌骨转移

Nimali P Withana, Galia Blum, Mansoureh Sameni, Clare Slaney, Arulselvi Anbalagan, Mary B Olive, Bradley N Bidwell, Laura Edgington, Ling Wang, Kamiar Moin, Bonnie F Sloane, Robin L Anderson, Matthew S Bogyo, Belinda S Parker