PANTHER: AZD8931, inhibitor of EGFR, ERBB2 and ERBB3 signalling, combined with FOLFIRI: a Phase I/II study to determine the importance of schedule and activity in colorectal cancer
PANTHER:AZD8931(EGFR、ERBB2 和 ERBB3 信号通路抑制剂)联合 FOLFIRI 方案:一项 I/II 期研究,旨在确定给药方案和疗效在结直肠癌治疗中的重要性
期刊:British Journal of Cancer
影响因子:6.8
doi:10.1038/s41416-022-02015-x
Propper, David J; Gao, Fangfei; Saunders, Mark P; Sarker, Debashis; Hartley, John A; Spanswick, Victoria J; Lowe, Helen L; Hackett, Louise D; Ng, Tony T; Barber, Paul R; Weitsman, Gregory E; Pearce, Sarah; White, Laura; Lopes, Andre; Forsyth, Sharon; Hochhauser, Daniel
肿瘤
肠癌
肿瘤免疫
ERBB2
信号转导
EGF
EGFR
ERBB3
NTH