日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Phenotypic characterization of P23H and S334ter rhodopsin transgenic rat models of inherited retinal degeneration

P23H 和 S334ter 视紫红质转基因大鼠遗传性视网膜变性模型的表型特征

LaVail, Matthew M; Nishikawa, Shimpei; Steinberg, Roy H; Naash, Muna I; Duncan, Jacque L; Trautmann, Nikolaus; Matthes, Michael T; Yasumura, Douglas; Lau-Villacorta, Cathy; Chen, Jeannie; Peterson, Ward M; Yang, Haidong; Flannery, John G

Long-term photoreceptor rescue in two rodent models of retinitis pigmentosa by adeno-associated virus delivery of Stanniocalcin-1

通过腺相关病毒递送斯钙素-1 对两种视网膜色素变性啮齿动物模型进行长期光感受器拯救

Gavin W Roddy, Douglas Yasumura, Michael T Matthes, Marcel V Alavi, Sanford L Boye, Robert H Rosa Jr, Michael P Fautsch, William W Hauswirth, Matthew M LaVail

Sphingolipid profile alters in retinal dystrophic P23H-1 rats and systemic FTY720 can delay retinal degeneration

视网膜营养不良 P23H-1 大鼠的鞘脂谱发生改变,全身性 FTY720 可延缓视网膜变性

Megan Stiles, Hui Qi, Eleanor Sun, Jeremy Tan, Hunter Porter, Jeremy Allegood, Charles E Chalfant, Douglas Yasumura, Michael T Matthes, Matthew M LaVail, Nawajes A Mandal

The Basic Domain of Herpes Simplex Virus 1 pUS9 Recruits Kinesin-1 To Facilitate Egress from Neurons

单纯疱疹病毒1型pUS9的基本结构域募集驱动蛋白-1以促进病毒从神经元中释放

Diefenbach, Russell J; Davis, April; Miranda-Saksena, Monica; Fernandez, Marian A; Kelly, Barbara J; Jones, Cheryl A; LaVail, Jennifer H; Xue, Jing; Lai, Joey; Cunningham, Anthony L

Ablation of Chop Transiently Enhances Photoreceptor Survival but Does Not Prevent Retinal Degeneration in Transgenic Mice Expressing Human P23H Rhodopsin

短暂性地消除 Chop 可增强表达人 P23H 视紫红质的转基因小鼠的光感受器存活率,但不能阻止视网膜退化。

Chiang, Wei-Chieh; Joseph, Victory; Yasumura, Douglas; Matthes, Michael T; Lewin, Alfred S; Gorbatyuk, Marina S; Ahern, Kelly; LaVail, Matthew M; Lin, Jonathan H

Gene Therapy for MERTK-Associated Retinal Degenerations

基因疗法治疗MERTK相关视网膜变性

LaVail, Matthew M; Yasumura, Douglas; Matthes, Michael T; Yang, Haidong; Hauswirth, William W; Deng, Wen-Tao; Vollrath, Douglas

Allele-Specific Inhibition of Rhodopsin With an Antisense Oligonucleotide Slows Photoreceptor Cell Degeneration

用反义寡核苷酸对视紫红质进行等位基因特异性抑制可减缓感光细胞退化

Susan F Murray, Ali Jazayeri, Michael T Matthes, Douglas Yasumura, Haidong Yang, Raechel Peralta, Andy Watt, Sue Freier, Gene Hung, Peter S Adamson, Shuling Guo, Brett P Monia, Matthew M LaVail, Michael L McCaleb

In Vivo Visualization of Endoplasmic Reticulum Stress in the Retina Using the ERAI Reporter Mouse

利用ERAI报告基因小鼠对视网膜内质网应激进行体内可视化

Alavi, Marcel V; Chiang, Wei-Chieh; Kroeger, Heike; Yasumura, Douglas; Matthes, Michael T; Iwawaki, Takao; LaVail, Matthew M; Gould, Douglas B; Lin, Jonathan H

Robust Endoplasmic Reticulum-Associated Degradation of Rhodopsin Precedes Retinal Degeneration

内质网相关视紫红质的强烈降解先于视网膜变性

Wei-Chieh Chiang, Heike Kroeger, Sanae Sakami, Carissa Messah, Douglas Yasumura, Michael T Matthes, Judith A Coppinger, Krzysztof Palczewski, Matthew M LaVail, Jonathan H Lin

Translational and posttranslational regulation of XIAP by eIF2α and ATF4 promotes ER stress-induced cell death during the unfolded protein response

eIF2α 和 ATF4 对 XIAP 的翻译和翻译后调控促进了未折叠蛋白反应过程中内质网应激诱导的细胞死亡

Nobuhiko Hiramatsu, Carissa Messah, Jaeseok Han, Matthew M LaVail, Randal J Kaufman, Jonathan H Lin