日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
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2025
2026
影响因子:
–

Cryo-EM structures of amyloid-β filaments with the Arctic mutation (E22G) from human and mouse brains

人脑和鼠脑中具有北极突变（E22G）的β-淀粉样蛋白丝的冷冻电镜结构

期刊:Acta Neuropathologica
影响因子:9.3
doi:10.1007/s00401-022-02533-1
Yang, Yang; Zhang, Wenjuan; Murzin, Alexey G; Schweighauser, Manuel; Huang, Melissa; Lövestam, Sofia; Peak-Chew, Sew Y; Saito, Takashi; Saido, Takaomi C; Macdonald, Jennifer; Lavenir, Isabelle; Ghetti, Bernardino; Graff, Caroline; Kumar, Amit; Nordberg, Agneta; Goedert, Michel; Scheres, Sjors H W
神经科学
发表日期：2023
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Cryo-EM structures of tau filaments from the brains of mice transgenic for human mutant P301S Tau

转基因小鼠（携带人类突变型 P301S Tau 蛋白）脑内 tau 丝的冷冻电镜结构

期刊:Acta Neuropathologica Communications
影响因子:5.7
doi:10.1186/s40478-023-01658-y
Schweighauser, Manuel; Murzin, Alexey G; Macdonald, Jennifer; Lavenir, Isabelle; Crowther, R Anthony; Scheres, Sjors H W; Goedert, Michel
神经科学
发表日期：2023
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Cryo-EM structures of amyloid-β 42 filaments from human brains

人脑中β-淀粉样蛋白42丝的冷冻电镜结构

期刊:Science
影响因子:45.8
doi:10.1126/science.abm7285
Yang, Yang; Arseni, Diana; Zhang, Wenjuan; Huang, Melissa; Lövestam, Sofia; Schweighauser, Manuel; Kotecha, Abhay; Murzin, Alexey G; Peak-Chew, Sew Y; Macdonald, Jennifer; Lavenir, Isabelle; Garringer, Holly J; Gelpi, Ellen; Newell, Kathy L; Kovacs, Gabor G; Vidal, Ruben; Ghetti, Bernardino; Ryskeldi-Falcon, Benjamin; Scheres, Sjors H W; Goedert, Michel
神经科学
发表日期：2022
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Assembly of transgenic human P301S Tau is necessary for neurodegeneration in murine spinal cord.

转基因人 P301S Tau 的组装是小鼠脊髓神经退行性变所必需的

期刊:Acta Neuropathologica Communications
影响因子:5.7
doi:10.1186/s40478-019-0695-5
Macdonald Jennifer A, Bronner Iraad F, Drynan Lesley, Fan Juan, Curry Annabelle, Fraser Graham, Lavenir Isabelle, Goedert Michel
神经科学
Human
发表日期：2019
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Peripheral administration of tau aggregates triggers intracerebral tauopathy in transgenic mice

外周注射tau蛋白聚集体可诱发转基因小鼠脑内tau蛋白病变。

期刊:Acta Neuropathologica
影响因子:9.3
doi:10.1007/s00401-013-1231-5
Clavaguera, Florence; Hench, Jürgen; Lavenir, Isabelle; Schweighauser, Gabriel; Frank, Stephan; Goedert, Michel; Tolnay, Markus
神经科学
发表日期：2014
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A novel in vivo model of tau propagation with rapid and progressive neurofibrillary tangle pathology: the pattern of spread is determined by connectivity, not proximity

一种新型体内tau蛋白传播模型，可观察到快速进展的神经原纤维缠结病理：传播模式由连接性决定，而非邻近性。

期刊:Acta Neuropathologica
影响因子:
doi:10.1007/s00401-014-1254-6
Ahmed, Zeshan; Cooper, Jane; Murray, Tracey K; Garn, Katya; McNaughton, Emily; Clarke, Hannah; Parhizkar, Samira; Ward, Mark A; Cavallini, Annalisa; Jackson, Samuel; Bose, Suchira; Clavaguera, Florence; Tolnay, Markus; Lavenir, Isabelle; Goedert, Michel; Hutton, Michael L; O'Neill, Michael J
发表日期：2014
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"Prion-like" templated misfolding in tauopathies

tau蛋白病中的“朊病毒样”模板错误折叠

期刊:Brain Pathology
影响因子:
doi:10.1111/bpa.12044
Clavaguera, Florence; Lavenir, Isabelle; Falcon, Ben; Frank, Stephan; Goedert, Michel; Tolnay, Markus
微生物学
发表日期：2013
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Analysis of tau phosphorylation and truncation in a mouse model of human tauopathy

在人类tau蛋白病的小鼠模型中分析tau蛋白磷酸化和截断情况

期刊:American Journal of Pathology
影响因子:3.6
doi:10.2353/ajpath.2008.070627
Delobel, Patrice; Lavenir, Isabelle; Fraser, Graham; Ingram, Esther; Holzer, Max; Ghetti, Bernardino; Spillantini, Maria Grazia; Crowther, R Anthony; Goedert, Michel
信号转导
磷酸化
发表日期：2008
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Detection of filamentous tau inclusions by the fluorescent Congo red derivative FSB [(trans,trans)-1-fluoro-2,5-bis(3-hydroxycarbonyl-4-hydroxy)styrylbenzene]

利用荧光刚果红衍生物 FSB [(反式,反式)-1-氟-2,5-双(3-羟基羰基-4-羟基)苯乙烯基苯] 检测丝状 tau 包涵体

期刊:
影响因子:
doi:10.1016/j.febslet.2008.02.025
Velasco, Ana; Fraser, Graham; Delobel, Patrice; Ghetti, Bernardino; Lavenir, Isabelle; Goedert, Michel
IF
发表日期：2008
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