Laver Derek R相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

Introduction of a single carboxylic acid converts the cyclic oligomeric depsipeptide ent-verticilide from a ryanodine receptor 2 (RyR2) inhibitor to RyR2 activator

引入单个羧酸基团可将环状低聚缩肽ent-verticilide从ryanodine受体2 (RyR2)抑制剂转化为RyR2激活剂。

期刊:Molecular Pharmacology

doi:10.1016/j.molpha.2025.100086

Do, Tri Q; Blackwell, Daniel J; Smith, Abigail N; Thorpe, Madelaine P; Rebbeck, Robyn T; Laver, Derek R; Johnston, Jeffrey N; Knollmann, Björn C

发表日期：2025

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Novel Ca2+ wave mechanisms in cardiac myocytes revealed by multiscale Ca2+ release model

多尺度Ca2+释放模型揭示心肌细胞中新型Ca2+波机制

期刊:Journal of General Physiology

影响因子:2.9

doi:10.1085/jgp.202413543

Vysma, Morris; Welsh, James S; Laver, Derek R

细胞生物学

发表日期：2025

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ent-Verticilide B1 Inhibits Type 2 Ryanodine Receptor Channels and is Antiarrhythmic in Casq2 (-/-) Mice

ent-Verticilide B1抑制2型兰尼碱受体通道，并在Casq2（-/-）小鼠中具有抗心律失常作用

期刊:Molecular Pharmacology

doi:10.1124/molpharm.123.000752

Gochman, Aaron; Do, Tri Q; Kim, Kyungsoo; Schwarz, Jacob A; Thorpe, Madelaine P; Blackwell, Daniel J; Ritschel, Paxton A; Smith, Abigail N; Rebbeck, Robyn T; Akers, Wendell S; Cornea, Razvan L; Laver, Derek R; Johnston, Jeffrey N; Knollmann, Bjorn C

发表日期：2024

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A bivalent remipede toxin promotes calcium release via ryanodine receptor activation

二价蜈蚣毒素通过激活兰尼碱受体促进钙释放。

期刊:Nature Communications

影响因子:15.7

doi:10.1038/s41467-023-36579-w

Maxwell, Michael J; Thekkedam, Chris; Lamboley, Cedric; Chin, Yanni K-Y; Crawford, Theo; Smith, Jennifer J; Liu, Junyu; Jia, Xinying; Vetter, Irina; Laver, Derek R; Launikonis, Bradley S; Dulhunty, Angela; Undheim, Eivind A B; Mobli, Mehdi

发表日期：2023

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ent -Verticilide B1 inhibits type 2 ryanodine receptor channels and is antiarrhythmic in Casq2-/- mice

ent-Verticilide B1抑制2型兰尼碱受体通道，并在Casq2-/-小鼠中具有抗心律失常作用。

doi:10.1101/2023.07.03.547578

Gochman, Aaron; Do, Tri Q; Kim, Kyungsoo; Schwarz, Jacob A; Thorpe, Madelaine P; Blackwell, Daniel J; Smith, Abigail N; Akers, Wendell S; Cornea, Razvan L; Laver, Derek R; Johnston, Jeffrey N; Knollmann, Bjorn C

发表日期：2023

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RYR2 Channel Inhibition Is the Principal Mechanism of Flecainide Action in CPVT

RYR2通道抑制是氟卡尼治疗儿茶酚胺敏感性室性心动过速的主要机制。

期刊:Circulation Research

影响因子:16.2

doi:10.1161/CIRCRESAHA.120.316819

Kryshtal, Dmytro O; Blackwell, Daniel J; Egly, Christian L; Smith, Abigail N; Batiste, Suzanne M; Johnston, Jeffrey N; Laver, Derek R; Knollmann, Bjorn C

发表日期：2021

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Regulation of the RyR channel gating by Ca(2+) and Mg(2)

Ca(2+)和Mg(2)对RyR通道门控的调节

期刊:Biophysical Reviews

影响因子:3.7

doi:10.1007/s12551-018-0433-4

发表日期：2018

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Pharmacological approaches that slow lymphatic flow as a snakebite first aid.

减缓淋巴流动的药物疗法作为蛇咬伤急救措施

期刊:PLoS Neglected Tropical Diseases

影响因子:3.4

doi:10.1371/journal.pntd.0002722

van Helden Dirk F, Thomas Paul A, Dosen Peter J, Imtiaz Mohammad S, Laver Derek R, Isbister Geoffrey K

发表日期：2014

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Amyloid-β protein impairs Ca2+ release and contractility in skeletal muscle

β-淀粉样蛋白会损害骨骼肌中的Ca2+释放和收缩力。

期刊:Neurobiology of Aging

影响因子:3.5

doi:10.1016/j.neurobiolaging.2008.11.003

Shtifman, Alexander; Ward, Christopher W; Laver, Derek R; Bannister, Mark L; Lopez, Jose R; Kitazawa, Masashi; LaFerla, Frank M; Ikemoto, Noriaki; Querfurth, Henry W

发表日期：2010

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Protein interactions involving the gamma2 large cytoplasmic loop of GABA(A) receptors modulate conductance

涉及GABA(A)受体γ2大胞质环的蛋白质相互作用调节电导

期刊:FASEB Journal

影响因子:4.2

doi:10.1096/fj.09-137042

Everitt, Andrea B; Seymour, Victoria A L; Curmi, John; Laver, Derek R; Gage, Peter W; Tierney, M Louise

发表日期：2009

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