Somatic CRISPR tumorigenesis and multiomic analysis reveal a pentose phosphate pathway disruption vulnerability in MPNSTs.
体细胞 CRISPR 致瘤性和多组学分析揭示了 MPNST 中磷酸戊糖途径破坏的脆弱性
期刊:Science Advances
影响因子:12.5
doi:10.1126/sciadv.adu2906
McGivney Gavin R, Brockman Qierra R, Borcherding Nicholas, Scherer Amanda, Rauckhorst Adam J, Gutierrez Wade R, Solst Shane R, Heer Collin D, Warrier Akshaya, Floyd Warren, Kirsch David G, Knepper-Adrian Vickie L, Laverty Emily A, Roughton Grace A, Spitz Douglas R, Taylor Eric B, Dodd Rebecca D
