日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Active Antigen-Specific Adaptive Immune Responses Are Shared among Patients with Progressive Fibrotic Interstitial Lung Disease

进行性纤维化间质性肺病患者均具有活跃的抗原特异性适应性免疫反应。

Velez, Tania E; Yoon, Young Me; Upadhyay, Vaibhav; Vazquez, Sara E; Lee, Cathryn T; Selvan, Kavitha C; Law, Christopher S; Blaine, Kelly M; Hollinger, Maile K; Decker, Donna M; Bingham, Grace C; Pastore, Christopher F; Bonham, Catherine A; Clark, Marcus R; Schoettler, Nathan R; Strek, Mary E; Guzy, Robert D; Adegunsoye, Ayodeji; Noth, Imre; Wolters, Paul J; Barker, Thomas H; Anderson, Mark S; DeRisi, Joseph L; Shum, Anthony K; Sperling, Anne I

The common HAQ STING allele prevents clinical penetrance of COPA syndrome.

常见的 HAQ STING 等位基因可阻止 COPA 综合征的临床表现

Simchoni Noa, Koide Shogo, Likhite Maryel, Kuchitsu Yoshihiko, Kadirvel Senkottuvelan, Law Christopher S, Elicker Brett M, Kurra Santosh, Wong Margaret Mei-Kay, Yuan Bo, Grossi Alice, Laxer Ronald M, Volpi Stefano, Dissanayake Dilan, Taguchi Tomohiko, Beck David B, Vogel Tiphanie P, Shum Anthony K

PhIP-Seq uncovers novel autoantibodies and unique endotypes in interstitial lung disease

PhIP-Seq技术揭示间质性肺疾病中的新型自身抗体和独特内型

Upadhyay, Vaibhav; Yoon, Young Me; Vazquez, Sara E; Velez, Tania E; Jones, Kirk D; Lee, Cathryn T; Law, Christopher S; Wolters, Paul J; Lee, Seoyeon; Yang, Monica M; Farrand, Erica; Noth, Imre; Strek, Mary E; Anderson, Mark; DeRisi, Joseph; Sperling, Anne I; Shum, Anthony K

A defect in COPI-mediated transport of STING causes immune dysregulation in COPA syndrome

COPI介导的STING转运缺陷会导致COPA综合征中的免疫失调。

Deng, Zimu; Chong, Zhenlu; Law, Christopher S; Mukai, Kojiro; Ho, Frances O; Martinu, Tereza; Backes, Bradley J; Eckalbar, Walter L; Taguchi, Tomohiko; Shum, Anthony K

Analysis of pulmonary features and treatment approaches in the COPA syndrome

COPA综合征的肺部特征及治疗方法分析

Tsui, Jessica L; Estrada, Oscar A; Deng, Zimu; Wang, Kristin M; Law, Christopher S; Elicker, Brett M; Jones, Kirk D; Dell, Sharon D; Gudmundsson, Gunnar; Hansdottir, Sif; Helfgott, Simon M; Volpi, Stefano; Gattorno, Marco; Waterfield, Michael R; Chan, Alice Y; Chung, Sharon A; Ley, Brett; Shum, Anthony K

COPA mutations impair ER-Golgi transport and cause hereditary autoimmune-mediated lung disease and arthritis

COPA基因突变会损害内质网-高尔基体运输,并导致遗传性自身免疫介导的肺部疾病和关节炎。

Watkin, Levi B; Jessen, Birthe; Wiszniewski, Wojciech; Vece, Timothy J; Jan, Max; Sha, Youbao; Thamsen, Maike; Santos-Cortez, Regie L P; Lee, Kwanghyuk; Gambin, Tomasz; Forbes, Lisa R; Law, Christopher S; Stray-Pedersen, Asbjørg; Cheng, Mickie H; Mace, Emily M; Anderson, Mark S; Liu, Dongfang; Tang, Ling Fung; Nicholas, Sarah K; Nahmod, Karen; Makedonas, George; Canter, Debra L; Kwok, Pui-Yan; Hicks, John; Jones, Kirk D; Penney, Samantha; Jhangiani, Shalini N; Rosenblum, Michael D; Dell, Sharon D; Waterfield, Michael R; Papa, Feroz R; Muzny, Donna M; Zaitlen, Noah; Leal, Suzanne M; Gonzaga-Jauregui, Claudia; Boerwinkle, Eric; Eissa, N Tony; Gibbs, Richard A; Lupski, James R; Orange, Jordan S; Shum, Anthony K

Cardiomyocyte-specific deletion of the vitamin D receptor gene results in cardiac hypertrophy.

心肌细胞特异性敲除维生素 D 受体基因会导致心脏肥大

Chen Songcang, Law Christopher S, Grigsby Christopher L, Olsen Keith, Hong Ting-Ting, Zhang Yan, Yeghiazarians Yerem, Gardner David G

Function of phenylalanine 259 and threonine 314 within the substrate binding pocket of the juvenile hormone esterase of Manduca sexta

烟草天蛾幼虫激素酯酶底物结合口袋中苯丙氨酸259和苏氨酸314的功能

Kamita, Shizuo G; Wogulis, Mark D; Law, Christopher S; Morisseau, Christophe; Tanaka, Hiromasa; Huang, Huazhang; Wilson, David K; Hammock, Bruce D

Vitamin D-dependent suppression of endothelin-induced vascular smooth muscle cell proliferation through inhibition of CDK2 activity

维生素D依赖性抑制内皮素诱导的血管平滑肌细胞增殖,其机制是通过抑制CDK2活性

Chen, Songcang; Law, Christopher S; Gardner, David G

A role for the cell cycle phosphatase Cdc25a in vitamin D-dependent inhibition of adult rat vascular smooth muscle cell proliferation

细胞周期磷酸酶Cdc25a在维生素D依赖性抑制成年大鼠血管平滑肌细胞增殖中的作用

Chen, Songcang; Law, Christopher S; Grigsby, Christopher L; Olsen, Keith; Gardner, David G