日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Publisher Correction: Toxoplasma effector TgROP1 establishes membrane contact sites with the endoplasmic reticulum during infection

出版商更正：弓形虫效应蛋白TgROP1在感染过程中与内质网建立膜接触位点。

期刊:Nature Microbiology
影响因子:19.4
doi:10.1038/s41564-025-02256-5
Mehra, Chahat; Alvarado Valverde, Jesús; Matias, Ana Margarida Nogueira; Torelli, Francesca; Medeiros, Tânia Catarina; Straub, Julian; Asaki, James D; Bradley, Peter J; Luck, Katja; Lawo, Steffen; Treeck, Moritz; Pernas, Lena
炎症/感染
发表日期：2026
文献求助 收藏

A Phase 1 Randomized Study: Garadacimab Pharmacokinetics, Safety, and Tolerability After Administration via Autoinjector/Pre-Filled Pen Versus Pre-Filled Syringe in Healthy Participants

一项 1 期随机研究：在健康受试者中，通过自动注射器/预充式注射笔与预充式注射器给药后，Garadacimab 的药代动力学、安全性和耐受性比较

期刊:Journal of Clinical Pharmacology
影响因子:2.3
doi:10.1002/jcph.70099
Glassman, Fiona; Lawo, John-Philip; Bica, Mihai Alexandru; Roberts, Anthony; Kormann, David; Chialda, Ligia; Miethke, Soeren; Dziadowiec, Iwona; Caltabiano, Stephen; Puchalski, Thomas
发表日期：2026
文献求助 收藏

Toxoplasma effector TgROP1 establishes membrane contact sites with the endoplasmic reticulum during infection

弓形虫效应蛋白TgROP1在感染过程中与内质网建立膜接触位点。

期刊:Nature Microbiology
影响因子:20.5
doi:10.1038/s41564-025-02193-3.
Chahat Mehra,Jesús Alvarado Valverde #,Ana Margarida Nogueira Matias #,Francesca Torelli,Tânia Catarina Medeiros,Julian Straub,James D Asaki,Peter J Bradley,Katja Luck,Steffen Lawo,Moritz Treeck,Lena Pernas
炎症/感染
发表日期：2025
文献求助 收藏

Long-term safety and efficacy of garadacimab for preventing hereditary angioedema attacks: Phase 3 open-label extension study

garadacimab预防遗传性血管性水肿发作的长期安全性和有效性：3期开放标签扩展研究

期刊:Allergy
影响因子:12
doi:10.1111/all.16351
Reshef, Avner; Hsu, Connie; Katelaris, Constance H; Li, Philip H; Magerl, Markus; Yamagami, Keiko; Guilarte, Mar; Keith, Paul K; Bernstein, Jonathan A; Lawo, John-Philip; Shetty, Harsha; Pollen, Maressa; Wieman, Lolis; Craig, Tim J
发表日期：2025
文献求助 收藏

Development of a conceptual model of early systemic sclerosis (scleroderma)

早期系统性硬化症（硬皮病）概念模型的建立

期刊:Orphanet Journal of Rare Diseases
影响因子:3.5
doi:10.1186/s13023-025-03917-8
Lenderking, William R; Ladd, Mary Kathleen; Barnes, Nicola; Braverman, Julia; Gasior, Maria; Hofmann, Jutta; Lawo, John-Phillip; Khanna, Dinesh
系统性硬化症
免疫/内分泌
发表日期：2025
文献求助 收藏

Population Pharmacokinetic/Pharmacodynamic and Exposure-Response Modeling of Garadacimab in Healthy Volunteers and Patients With Hereditary Angioedema

在健康志愿者和遗传性血管性水肿患者中开展加拉达西单抗的群体药代动力学/药效学和暴露-反应模型研究

期刊:Cpt-Pharmacometrics & Systems Pharmacology
影响因子:3
doi:10.1002/psp4.70009
Garcia, Ramon; Cheng, Shen; Glassman, Fiona; Sharma, Ankur; De Miguel-Lillo, Bernardo; Wiens, Matthew; Johnston, Curtis; Lawo, John-Philip; Pragst, Ingo; French, Jonathan; Polhamus, Dan; Nandy, Partha
发表日期：2025
文献求助 收藏

Pharmacokinetics, Pharmacodynamics, and Safety of Subcutaneous and Intravenous Garadacimab Following Single-Dose Administration in Healthy Japanese and White Adults

健康日本人和白种人成年人单次皮下和静脉注射Garadacimab后的药代动力学、药效学和安全性

期刊:Journal of Clinical Pharmacology
影响因子:2.3
doi:10.1002/jcph.6162
Glassman, Fiona; Lawo, John-Philip; Bica, Mihai Alexandru; Roberts, Anthony; Pawaskar, Dipti; Akama, Hideto; Jain, Meena; Goodson, Summer
发表日期：2025
文献求助 收藏

A prospective randomized clinical trial to evaluate wound healing, cosmetic and functional results as well as postoperative adverse events comparing two types of dressing technique after hypospadias repair

一项前瞻性随机临床试验，旨在评估尿道下裂修复术后两种敷料技术在伤口愈合、美容和功能效果以及术后不良事件方面的差异。

期刊:Pediatric Surgery International
影响因子:1.6
doi:10.1007/s00383-025-06063-1
Lawo, Kristin; Feller, Dominique; Klein, Birgit S; Holland-Cunz, Stefan G; Frech-Dörfler, Martina
发表日期：2025
文献求助 收藏

ERK pathway agonism for cancer therapy: evidence, insights, and a target discovery framework

ERK通路激动剂在癌症治疗中的应用：证据、见解和靶点发现框架

期刊:npj Precision Oncology
影响因子:8
doi:10.1038/s41698-024-00554-5
Timofeev, Oleg; Giron, Philippe; Lawo, Steffen; Pichler, Martin; Noeparast, Maxim
肿瘤免疫
信号转导
肿瘤
MAPK/ERK
发表日期：2024
文献求助 收藏

Timing of Onset of Garadacimab for Preventing Hereditary Angioedema Attacks

Garadacimab预防遗传性血管性水肿发作的起效时间

期刊:Clinical and Experimental Allergy
影响因子:5.2
doi:10.1111/cea.14568
Staubach, Petra; Tachdjian, Raffi; Li, H Henry; Hakl, Roman; Aygören-Pürsün, Emel; Wieman, Lolis; Lawo, John-Philip; Craig, Timothy J
发表日期：2024
文献求助 收藏