日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

2-Aminomethylene-5-sulfonylthiazole Inhibitors of Lysyl Oxidase (LOX) and LOXL2 Show Significant Efficacy in Delaying Tumor Growth.

2-氨基亚甲基-5-磺酰噻唑类赖氨酰氧化酶(LOX)和LOXL2抑制剂在延缓肿瘤生长方面显示出显著疗效

Smithen Deborah A, Leung Leo M H, Challinor Mairi, Lawrence Rae, Tang HaoRan, Niculescu-Duvaz Dan, Pearce Simon P, Mcleary Robert, Lopes Filipa, Aljarah Mohammed, Brown Michael, Johnson Louise, Thomson Graeme, Marais Richard, Springer Caroline

Core chemotype diversification in the HIV-1 entry inhibitor class using field-based bioisosteric replacement

利用基于场的生物等排置换技术实现HIV-1进入抑制剂类核心化学型多样化

Tuyishime, Marina; Lawrence, Rae; Cocklin, Simon

Identification of a small molecule HIV-1 inhibitor that targets the capsid hexamer

鉴定出一种靶向衣壳六聚体的小分子HIV-1抑制剂

Xu, Jimmy P; Branson, Jeffrey D; Lawrence, Rae; Cocklin, Simon

Discovery and optimization of novel small-molecule HIV-1 entry inhibitors using field-based virtual screening and bioisosteric replacement

利用基于场的虚拟筛选和生物等排置换法发现和优化新型小分子HIV-1进入抑制剂

Tuyishime, Marina; Danish, Matt; Princiotto, Amy; Mankowski, Marie K; Lawrence, Rae; Lombart, Henry-Georges; Esikov, Kirill; Berniac, Joel; Liang, Kuang; Ji, Jingjing; Ptak, Roger G; Madani, Navid; Cocklin, Simon