PRPF8-mediated dysregulation of hBrr2 helicase disrupts human spliceosome kinetics and 5´-splice-site selection causing tissue-specific defects
PRPF8介导的hBrr2解旋酶失调会破坏人类剪接体的动力学和5'剪接位点的选择，从而导致组织特异性缺陷。
期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-024-47253-0
Atkinson, Robert; Georgiou, Maria; Yang, Chunbo; Szymanska, Katarzyna; Lahat, Albert; Vasconcelos, Elton J R; Ji, Yanlong; Moya Molina, Marina; Collin, Joseph; Queen, Rachel; Dorgau, Birthe; Watson, Avril; Kurzawa-Akanbi, Marzena; Laws, Ross; Saxena, Abhijit; Shyan Beh, Chia; Siachisumo, Chileleko; Goertler, Franziska; Karwatka, Magdalena; Davey, Tracey; Inglehearn, Chris F; McKibbin, Martin; Lührmann, Reinhard; Steel, David H; Elliott, David J; Armstrong, Lyle; Urlaub, Henning; Ali, Robin R; Grellscheid, Sushma-Nagaraja; Johnson, Colin A; Mozaffari-Jovin, Sina; Lako, Majlinda
