Synthesis and Characterization of ULK1/2 Kinase Inhibitors that Inhibit Autophagy and Upregulate Expression of Major Histocompatibility Complex I for the Treatment of Non-Small Cell Lung Cancer
合成和表征抑制自噬并上调主要组织相容性复合体I表达的ULK1/2激酶抑制剂,用于治疗非小细胞肺癌
期刊:
影响因子:
doi:10.1101/2025.09.05.674519
Layng, Fabiana Izidro A L; Ren, Huiyu; Bakas, Nicole A; Panickar, Dhanya R; Lambert, Lester J; Celeridad, Maria; Wu, Jiaqian; De Backer, Laurent; Chandrachud, Preeti; Limpert, Allison S; Vamos, Mitchell; Chaikuad, Apirat; Verdugo, Betsaida B; Hagan, Patrick M; Brun, Sonja N; Tautz, Lutz; Knapp, Stefan; Shaw, Reuben J; Salvesen, Guy S; Sheffler, Douglas J; Cosford, Nicholas D P
信号转导
细胞生物学
自噬
ULK1
Autophagy
肺癌
肿瘤
肿瘤免疫