日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Structural pathway for PI3-kinase regulation by VPS15 in autophagy

VPS15在自噬中调控PI3激酶的结构通路

Cook, Annan S I; Chen, Minghao; Nguyen, Thanh N; Cabezudo, Ainara Claveras; Khuu, Grace; Rao, Shanlin; Garcia, Samantha N; Yang, Mingxuan; Iavarone, Anthony T; Ren, Xuefeng; Lazarou, Michael; Hummer, Gerhard; Hurley, James H

Optineurin is an adaptor protein for ubiquitinated substrates in Golgi membrane-associated degradation

Optineurin 是一种衔接蛋白,用于介导高尔基体膜相关降解过程中泛素化底物的降解。

Nibe-Shirakihara, Yoichi; Honda, Shinya; Arakawa, Satoko; Torii, Satoru; Sakurai, Hajime Tajima; Yamaguchi, Hirofumi; Oshima, Shigeru; Okamoto, Ryuichi; Lazarou, Michael; Kawakami, Hideshi; Shimizu, Shigeomi

Structure and activation of the human autophagy-initiating ULK1C:PI3KC3-C1 supercomplex.

人类自噬起始 ULK1C:PI3KC3-C1 超复合物的结构和激活。

Chen Minghao, Nguyen Thanh N, Ren Xuefeng, Khuu Grace, Cook Annan S I, Zhao Yuanchang, Yildiz Ahmet, Lazarou Michael, Hurley James H

AI-directed voxel extraction and volume EM identify intrusions as sites of mitochondrial contact

人工智能引导的体素提取和体积电镜技术将入侵物识别为线粒体接触位点。

Padman, Benjamin S; Lindblom, Runa S J; Lazarou, Michael

The mitophagy receptors BNIP3 and NIX mediate tight attachment and expansion of the isolation membrane to mitochondria.

线粒体自噬受体 BNIP3 和 NIX 介导隔离膜与线粒体的紧密连接和扩张

Yamashita Shun-Ichi, Arai Ritsuko, Hada Hiroshi, Padman Benjamin Scott, Lazarou Michael, Chan David C, Kanki Tomotake, Waguri Satoshi

The TECPR1:ATG5-ATG12 complex conjugates LC3/ATG8 to damaged lysosomes that expose luminal glycans in response to osmotic imbalance.

TECPR1:ATG5-ATG12 复合物将 LC3/ATG8 连接到受损的溶酶体上,从而在渗透压失衡时暴露腔内聚糖

Wang Yingxue, Jefferson Matthew, Ramos Maria, Whelband Matthew, Kreuzer Kristin, Khuu Grace, Lazarou Michael, Mccoll James, Lazenby James, Whitchurch Cynthia B, Verkade Paul, Mayer Ulrike, Wileman Thomas

A guide to membrane atg8ylation and autophagy with reflections on immunity

膜活化和自噬指南及其对免疫的影响

Deretic, Vojo; Lazarou, Michael

Defective lysosome reformation during autophagy causes skeletal muscle disease

自噬过程中溶酶体重塑缺陷会导致骨骼肌疾病

McGrath, Meagan J; Eramo, Matthew J; Gurung, Rajendra; Sriratana, Absorn; Gehrig, Stefan M; Lynch, Gordon S; Lourdes, Sonia Raveena; Koentgen, Frank; Feeney, Sandra J; Lazarou, Michael; McLean, Catriona A; Mitchell, Christina A

ATG8ylation of proteins: A way to cope with cell stress?

蛋白质的 ATG8 化:一种应对细胞应激的方式?

Carosi, Julian M; Nguyen, Thanh N; Lazarou, Michael; Kumar, Sharad; Sargeant, Timothy J

Rebellious autophagy proteins bypass ATG8 lipidation, taking their own path to autophagic degradation

叛逆的自噬蛋白绕过ATG8脂化,走上它们自己的自噬降解途径。

Nguyen, Thanh Ngoc; Lazarou, Michael