日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Multi-Omics Reveals Mechanisms of Metabolic Rejuvenation in Aged Mice and Pre-Frail Older Men by Losartan

多组学揭示氯沙坦在老年小鼠和衰弱前期老年男性中促进代谢复苏的机制

Bene, Michael R; Zhang, Cissy; Westbrook, Reyhan; Gabrawy, Mariann; Marx, Ruth; Wu, Yuqiong; Khadeer, Mohammed; Ubaida-Mohien, Ceereena; Ferrucci, Luigi; Moaddel, Ruin; Le, Anne; Walston, Jeremy D; Lee, Jessica L; Abadir, Peter M

Frailty phenotype reveals heterogeneity in aging and distinct taurine associations

衰弱表型揭示了衰老过程中的异质性以及与牛磺酸的不同关联

Kim, April; Keener, Rebecca; Omdahl, Ashton; Bene, Michael; Westbrook, Reyhan; Le, Anne; Zhang, Cissy; Khare, Pratik; Khadeer, Mohammed; Ferrucci, Luigi; Moaddel, Ruin; Battle, Alexis; Abadir, Peter

Metabolic reprogramming by caloric restriction enhances acute phase virological control and reduces chronic inflammation in SIV-infected rhesus macaques

通过热量限制进行代谢重编程可增强SIV感染恒河猴的急性期病毒控制并减少慢性炎症

Suresh Babu, Naveen; Perdios, Chrysostomos; Hallmets, Maggie; Brown, Anna T; Coleman, Celeste; Fennessey, Christine M; Allers, Carolina; Moström, Matilda J; Khare, Pratik; Zhang, Cissy; Smith, Brandon T; Golden, Nadia A; Myers, Adam; Doyle-Meyers, Lara; Blaney, Alexandra; Blair, Robert V; Saied, Ahmad A; Colman, Ricki; Keele, Brandon F; Le, Anne; Palmer, Clovis S; Mudd, Joseph C

Dual regulation of mitochondrial fusion by Parkin-PINK1 and OMA1.

Parkin-PINK1 和 OMA1 对线粒体融合的双重调控

Yamada Tatsuya, Ikeda Arisa, Murata Daisuke, Wang Hu, Zhang Cissy, Khare Pratik, Adachi Yoshihiro, Ito Fumiya, Quirós Pedro M, Blackshaw Seth, López-Otín Carlos, Langer Thomas, Chan David C, Le Anne, Dawson Valina L, Dawson Ted M, Iijima Miho, Sesaki Hiromi

Gene therapy enhances deoxyribonuclease I treatment in antimyeloperoxidase glomerulonephritis.

基因疗法增强了抗髓过氧化物酶肾小球肾炎中脱氧核糖核酸酶 I 的治疗效果

Cao Le Anne, Oudin Virginie, Dick Jonathan, Alikhan Maliha A, Gottschalk Timothy A, Lu Lu, Lawlor Kate E, Koo Yuk Cheong Daniel, Mandwie Mawj, Alexander Ian E, Kitching A R, Gan Poh-Yi, Logan Grant J, O'Sullivan Kim M

Examining structure-activity relationships of ManNAc analogs used in the metabolic glycoengineering of human neural stem cells.

研究用于人类神经干细胞代谢糖工程的 ManNAc 类似物的构效关系

Dammen-Brower Kris, Arbogast Olivia, Zhu Stanley, Qiu Chunfang, Zhang Cissy, Khare Pratik, Le Anne, Jia Xiaofeng, Yarema Kevin J

Neutralizing the Th1 effector cytokines, IFN-γ and TNF-α, attenuates established experimental autoimmune anti-myeloperoxidase glomerulonephritis

中和 Th1 效应细胞因子 IFN-γ 和 TNF-α 可减轻已建立的实验性自身免疫性抗髓过氧化物酶肾小球肾炎。

Nagai, Kei; Koo Yuk Cheong, Daniel; Cao Le, Anne; Tan, Diana Shu Yee; Ooi, Joshua Daniel; Gan, Poh-Yi

Methylated Arginine Metabolites as Biomarkers for Clinical Status and Response to Type 5 Phosphodiesterase Inhibition in Patients With Fontan Circulation.

甲基化精氨酸代谢物作为Fontan循环患者临床状态和对5型磷酸二酯酶抑制剂反应的生物标志物

Cedars Ari, Manlhiot Cedric, Chinni Bhargava Kumar, Opotowsky Alexander R, Becker Kristian, Le Anne, Khare Pratik, Love Ko Jong, Everett Allen, Kutty Shelby, Russell Mark W, Payne R Mark, Atz Andrew M, McCrindle Brian W, Rathod Rahul H, Lewis Matthew, Goldberg David, Hill Kevin, Ploutz Michelle, Detterich Jon, Schumacher Kurt, Whitehill Robert, Penny Daniel J, Cartoski Mark, Sullivan Rachel, Files Matthew, Garg Ruchira, Wagner Jonathan, Jacobsen Roni, Nowlen Todd, Fletcher Scott, Conway Jennifer, Kim Gi Boem, Wu Fred, Zak Victor

Site-specific ERα phosphorylation determines sex-dependent metabolic, reproductive, and body-compositional phenotypes in mice

小鼠中ERα位点特异性磷酸化决定了其性别依赖性的代谢、生殖和身体组成表型。

Zou, Binghao; Williams, Jarvis; Landau, Madeleine B; Lin, Weiqiang; Fell, Sallie; Yang, Ziqi; Jones, MaryJane; Blair, Robert; Steele, Chad H; Khare, Pratik; Zhang, Cissy; Le, Anne; Anbalagan, Muralidharan; Rowan, Brian G

Viral reservoir seeding and neurological metabolic dysregulation in early-life immunodeficiency virus infection

早期免疫缺陷病毒感染中的病毒库建立和神经代谢紊乱

Ma, Li; Blair, Robert; Liu, Yao-Zhong; Wang, Xiaolei; Vincent, Eunice; Yu, Christopher; Doyle-Meyers, Lara A; Zhang, Cissy; Saied, Ahmad; Le, Anne; Veazey, Ronald S; Yu, Qigui; Xu, Huanbin