Le Lu Q相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

Disruption of Krox20-Notch1 signaling blocks meibomian gland development and homeostasis leading to dry eye disease.

Krox20-Notch1信号传导的破坏会阻碍睑板腺的发育和稳态，从而导致干眼症。

期刊:Nature Communications

影响因子:15.7

doi:10.1038/s41467-025-66740-6

Zhang Yumeng, Tchegnon Edem, Ghotbi Elnaz, Chen Zhiguo, Moye Stefanie L, He Yi, McKay RenÃ©e M, Le Lu Q

发育与干细胞

发表日期：2025

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Corrigendum for Humanized neurofibroma model from induced pluripotent stem cells delineates tumor pathogenesis and developmental origins

关于“利用诱导多能干细胞构建人源化神经纤维瘤模型阐明肿瘤发病机制和发育起源”的更正

期刊:Journal of Clinical Investigation

影响因子:13.6

doi:10.1172/JCI199700

Mo, Juan; Anastasaki, Corina; Chen, Zhiguo; Shipman, Tracey; Papke, Jason; Yin, Kevin; Gutmann, David H; Le, Lu Q

细胞生物学

发育与干细胞

发表日期：2025

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TGFÎ²-dependent signaling drives tumor growth and aberrant extracellular matrix dynamics in NF1-associated plexiform neurofibroma.

TGFβ依赖性信号传导驱动NF1相关丛状神经纤维瘤的肿瘤生长和异常的细胞外基质动力学

期刊:Science Advances

影响因子:12.5

doi:10.1126/sciadv.adu0772

Abu-Sultanah Mohannad, Zhou Zhuan, Jiang Chunhui, Mitchell Dana K, Bessler Waylan K, Jiang Li, Li Xiaohong, Qian Shaomin, Smith Abbi E, Mang Henry E, White Emily E, Ciesielski Marisa D, Hickey Brooke E, Brewster Kylee M, Sandusky George E, Masters Andi, Angus Steven P, Clapp D Wade, Le Lu Q, Rhodes Steven D

细胞生物学

发表日期：2025

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Post-Translational Regulation of Transcription Factor KROX20 in Epithelial Stem Cells

上皮干细胞中转录因子KROX20的翻译后调控

期刊:Journal of Investigative Dermatology

影响因子:5.7

doi:10.1016/j.jid.2025.05.009

Ghotbi, Elnaz; Tchegnon, Edem; Zhang, Yumeng; McKay, Renee M; Le, Lu Q

细胞生物学

发育与干细胞

发表日期：2025

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Using Durometers to Quantify Stiffness as an Outcome Measure for Cutaneous Neurofibroma in Neurofibromatosis Type 1

利用硬度计量化皮肤硬度作为1型神经纤维瘤病患者皮肤神经纤维瘤的疗效指标

期刊:JID Innovations

doi:10.1016/j.xjidi.2025.100380

Chamseddin, Bahir; McKay, Renee M; Jin, Ruyun; Zhu, Hong; Le, Lu Q

发表日期：2025

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Accounting for Biological Sex and Gender Identity in the Pathogenesis, Artistic Depictions, and Quality of Life in Neurofibromatosis Type 1

神经纤维瘤病1型的发病机制、艺术表现和生活质量中生物性别和性别认同的因素

期刊:JID Innovations

doi:10.1016/j.xjidi.2025.100393

Kuchimanchi, Nidhi; McKay, Renee M; Le, Lu Q

发表日期：2025

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Stem cell modeling of nervous system tumors

神经系统肿瘤的干细胞建模

期刊:Disease Models & Mechanisms

影响因子:3.3

doi:10.1242/dmm.050533

Furnari, Frank B; Anastasaki, Corina; Bian, Shan; Fine, Howard A; Koga, Tomoyuki; Le, Lu Q; Rodriguez, Fausto J; Gutmann, David H

细胞生物学

发育与干细胞

发表日期：2024

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Malignant melanoma developing in a pre-existing cutaneous neurofibroma from a patient with neurofibromatosis type 1

一例1型神经纤维瘤病患者，其原有皮肤神经纤维瘤内发生恶性黑色素瘤

期刊:JAAD Case Reports

doi:10.1016/j.jdcr.2024.09.022

Moye, Stefanie L; Knowles, Ariel; Vandergriff, Travis; Le, Lu Q

发表日期：2024

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Cutaneous Neurofibroma Heterogeneity: Factors that Influence Tumor Burden in Neurofibromatosis Type 1

皮肤神经纤维瘤异质性：影响1型神经纤维瘤病肿瘤负荷的因素

期刊:Journal of Investigative Dermatology

影响因子:5.7

doi:10.1016/j.jid.2022.12.027

Jiang, Chunhui; McKay, Renée M; Lee, Sang Y; Romo, Carlos G; Blakeley, Jaishri O; Haniffa, Muzlifah; Serra, Eduard; Steensma, Matthew R; Largaespada, David; Le, Lu Q

发表日期：2023

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Existing and Developing Preclinical Models for Neurofibromatosis Type 1-Related Cutaneous Neurofibromas

现有和正在开发的1型神经纤维瘤病相关皮肤神经纤维瘤的临床前模型

期刊:Journal of Investigative Dermatology

影响因子:5.7

doi:10.1016/j.jid.2023.01.042

Staedtke, Verena; Topilko, Piotr; Le, Lu Q; Grimes, Kevin; Largaespada, David A; Cagan, Ross L; Steensma, Matthew R; Stemmer-Rachamimov, Anat; Blakeley, Jaishri O; Rhodes, Steven D; Ly, Ina; Romo, Carlos G; Lee, Sang Y; Serra, Eduard

发表日期：2023

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