日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Prediction of Monoclonal Antibody Pharmacokinetics in Pediatric Populations Using PBPK Modeling and Simulation

利用PBPK建模和模拟预测单克隆抗体在儿科人群中的药代动力学

期刊:Pharmaceutics
影响因子:5.5
doi:10.3390/pharmaceutics17070884
Zunino, Chiara; Gualano, Virginie; Zhou, Haiying; Lukacova, Viera; Le Merdy, Maxime
单克隆抗体
发表日期：2025
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Mechanistic Modeling of Intramuscular Administration of a Long-acting Injectable Accounting for Tissue Response At the Depot Site

肌内注射长效注射剂的机制模型，考虑药物储存部位的组织反应

期刊:AAPS Journal
影响因子:3.7
doi:10.1208/s12248-025-01171-1
Silva, Daniela A; Le Merdy, Maxime; Mullin, James; Malavia, Nilesh; Alam, Khondoker; Tsakalozou, Eleftheria; Al Shoyaib, Abdullah; Wang, Yan; Burgess, Diane; Lukacova, Viera
发表日期：2025
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Clinical Ocular Exposure Extrapolation for a Complex Ophthalmic Suspension Using Physiologically Based Pharmacokinetic Modeling and Simulation

基于生理药代动力学建模和模拟的复杂眼用混悬液临床眼部暴露量外推

期刊:Pharmaceutics
影响因子:5.5
doi:10.3390/pharmaceutics16070914
Le Merdy, Maxime; Spires, Jessica; Tan, Ming-Liang; Zhao, Liang; Lukacova, Viera
发表日期：2024
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Development of Mechanistic In Vitro-In Vivo Extrapolation to Support Bioequivalence Assessment of Long-Acting Injectables

开发体外-体内机制外推法以支持长效注射剂的生物等效性评价

期刊:Pharmaceutics
影响因子:5.5
doi:10.3390/pharmaceutics16040552
Amaral Silva, Daniela; Le Merdy, Maxime; Alam, Khondoker Dedarul; Wang, Yan; Bao, Quanying; Malavia, Nilesh; Burgess, Diane; Lukacova, Viera
发表日期：2024
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PBPK Modeling Approach to Predict the Behavior of Drugs Cleared by Metabolism in Pregnant Subjects and Fetuses

利用生理药代动力学模型预测药物在孕妇和胎儿体内代谢清除的行为

期刊:Pharmaceutics
影响因子:
doi:10.3390/pharmaceutics16010096
Le Merdy, Maxime; Szeto, Ke Xu; Perrier, Jeremy; Bolger, Michael B; Lukacova, Viera
代谢
发表日期：2024
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Mechanistic modeling of ophthalmic, nasal, injectable, and implant generic drug products: A workshop summary report

眼科、鼻腔、注射剂和植入剂仿制药的机理建模：研讨会总结报告

期刊:Cpt-Pharmacometrics & Systems Pharmacology
影响因子:3
doi:10.1002/psp4.12952
Tan, Ming-Liang; Chandran, Sajeev; Jereb, Rebeka; Alam, Khondoker; Bies, Robert; Kozak, Darby; Walenga, Ross; Le Merdy, Maxime; Babiskin, Andrew
发表日期：2023
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PBPK Modeling Approach to Predict the Behavior of Drugs Cleared by Kidney in Pregnant Subjects and Fetus

利用生理药代动力学模型预测药物在孕妇和胎儿体内经肾脏清除的行为

期刊:AAPS Journal
影响因子:3.7
doi:10.1208/s12248-021-00603-y
Szeto, Ke Xu; Le Merdy, Maxime; Dupont, Benjamin; Bolger, Michael B; Lukacova, Viera
发表日期：2021
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