Elevated levels of FMRP-target MAP1B impair human and mouse neuronal development and mouse social behaviors via autophagy pathway
FMRP 靶标 MAP1B 水平升高会通过自噬途径损害人类和小鼠的神经元发育以及小鼠的社交行为
期刊:Nature Communications
影响因子:14.7
doi:10.1038/s41467-023-39337-0
Yu Guo, Minjie Shen, Qiping Dong, Natasha M Méndez-Albelo, Sabrina X Huang, Carissa L Sirois, Jonathan Le, Meng Li, Ezra D Jarzembowski, Keegan A Schoeller, Michael E Stockton, Vanessa L Horner, André M M Sousa, Yu Gao; Birth Defects Research Laboratory; Jon E Levine, Daifeng Wang, Qiang Chang, Xiny
信号转导
神经
细胞生物学
Autophagy
Mouse