日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A Brain-Permeable Aminosterol Regulates Cell Membranes to Mitigate the Toxicity of Diverse Pore-Forming Agents

一种可透过血脑屏障的氨基甾醇通过调节细胞膜来减轻多种成孔剂的毒性

Kreiser, Ryan P; Wright, Aidan K; Sasser, Liam R; Rinauro, Dillon J; Gabriel, Justus M; Hsu, Claire M; Hurtado, Jorge A; McKenzie, Tristan L; Errico, Silvia; Albright, J Alex; Richardson, Lance; Jaffett, Victor A; Riegner, Dawn E; Nguyen, Lam T; LeForte, Kathleen; Zasloff, Michael; Hollows, Jared E; Chiti, Fabrizio; Vendruscolo, Michele; Limbocker, Ryan

Squalamine and Its Derivatives Modulate the Aggregation of Amyloid-β and α-Synuclein and Suppress the Toxicity of Their Oligomers

鲨胺及其衍生物调节β-淀粉样蛋白和α-突触核蛋白的聚集,并抑制其寡聚体的毒性

Limbocker, Ryan; Staats, Roxine; Chia, Sean; Ruggeri, Francesco S; Mannini, Benedetta; Xu, Catherine K; Perni, Michele; Cascella, Roberta; Bigi, Alessandra; Sasser, Liam R; Block, Natalie R; Wright, Aidan K; Kreiser, Ryan P; Custy, Edward T; Meisl, Georg; Errico, Silvia; Habchi, Johnny; Flagmeier, Patrick; Kartanas, Tadas; Hollows, Jared E; Nguyen, Lam T; LeForte, Kathleen; Barbut, Denise; Kumita, Janet R; Cecchi, Cristina; Zasloff, Michael; Knowles, Tuomas P J; Dobson, Christopher M; Chiti, Fabrizio; Vendruscolo, Michele

Therapeutic Strategies to Reduce the Toxicity of Misfolded Protein Oligomers

降低错误折叠蛋白寡聚体毒性的治疗策略

Kreiser, Ryan P; Wright, Aidan K; Block, Natalie R; Hollows, Jared E; Nguyen, Lam T; LeForte, Kathleen; Mannini, Benedetta; Vendruscolo, Michele; Limbocker, Ryan

Bivalent engagement of endothelial surface antigens is critical to prolonged surface targeting and protein delivery in vivo

内皮表面抗原的双价结合对于延长体内表面靶向和蛋白质递送至关重要

R Yu Kiseleva, P G Glassman, K M LeForte, L R Walsh, C H Villa, V V Shuvaev, J W Myerson, P A Aprelev, O A Marcos-Contreras, V R Muzykantov, C F Greineder