日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

The Engineered Lysin CF-370 Is Active Against Antibiotic-Resistant Gram-Negative Pathogens In Vitro and Synergizes With Meropenem in Experimental Pseudomonas aeruginosa Pneumonia.

工程化赖氨酸 CF-370 在体外对耐抗生素革兰氏阴性病原体具有活性，并且在实验性铜绿假单胞菌肺炎中与美罗培南具有协同作用

期刊:Journal of Infectious Diseases
影响因子:4.5
doi:10.1093/infdis/jiae027
Sauve Karen, Watson Aubrey, Oh Jun T, Swift Steven, Vila-Farres Xavier, Abdelhady Wessam, Xiong Yan Q, LeHoux Dario, Woodnutt Gary, Bayer Arnold S, Schuch Raymond
免疫/内分泌
发表日期：2024
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In vitro activity of exebacase against methicillin-resistant Staphylococcus aureus biofilms on orthopedic Kirschner wires

体外研究 exebacase 对骨科克氏针上耐甲氧西林金黄色葡萄球菌生物膜的活性

期刊:BMC Research Notes
影响因子:1.7
doi:10.1186/s13104-023-06468-y
Karau, Melissa J; Mandrekar, Jay; Lehoux, Dario; Schuch, Raymond; Cassino, Cara; Patel, Robin
微生物学
发表日期：2023
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Locally delivered antistaphylococcal lysin exebacase or CF-296 is active in methicillin-resistant Staphylococcus aureus implant-associated osteomyelitis

局部应用抗葡萄球菌溶菌酶 exebacase 或 CF-296 对耐甲氧西林金黄色葡萄球菌植入物相关性骨髓炎有效。

期刊:Journal of Bone and Joint Infection
影响因子:2.8
doi:10.5194/jbji-7-169-2022
Karau, Melissa; Schmidt-Malan, Suzannah; Mandrekar, Jay; Lehoux, Dario; Schuch, Raymond; Cassino, Cara; Patel, Robin
骨髓炎
发表日期：2022
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Activity of Lysin CF-296 Alone and in Addition to Daptomycin in a Rat Model of Experimental Methicillin-Resistant Staphylococcus aureus Osteomyelitis

赖氨酸CF-296单独使用及与达托霉素联用在实验性耐甲氧西林金黄色葡萄球菌骨髓炎大鼠模型中的活性

期刊:Antimicrobial Agents and Chemotherapy
影响因子:4.5
doi:10.1128/AAC.00117-21
Karau, Melissa J; Schmidt-Malan, Suzannah M; Mandrekar, Jay; Lehoux, Dario; Schuch, Raymond; Cassino, Cara; Patel, Robin
Rat
骨髓炎
发表日期：2021
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Exebacase in Addition to Daptomycin against MRSA

除达托霉素外，Exebacase 还可用于治疗耐甲氧西林金黄色葡萄球菌感染。

期刊:Antimicrobial Agents and Chemotherapy
影响因子:4.5
doi:10.1128/AAC.00128-21
Kebriaei, Razieh; Stamper, Kyle C; Lev, Katherine L; Morrisette, Taylor; Abdul-Mutakabbir, Jacinda C; Schuch, Raymond; Lehoux, Dario; Rybak, Michael J
炎症/感染
发表日期：2021
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Effect of the Lysin Exebacase on Cardiac Vegetation Progression in a Rabbit Model of Methicillin-Resistant Staphylococcus aureus Endocarditis as Determined by Echocardiography

溶菌酶Exebacase对耐甲氧西林金黄色葡萄球菌心内膜炎兔模型心脏赘生物进展的影响（超声心动图测定）

期刊:Antimicrobial Agents and Chemotherapy
影响因子:4.5
doi:10.1128/AAC.00482-20
Shah, Sonia U; Xiong, Yan Q; Abdelhady, Wessam; Iwaz, James; Pak, Youngju; Schuch, Raymond; Cassino, Cara; Lehoux, Dario; Bayer, Arnold S
Rabbit
发表日期：2020
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Exebacase in Addition to Daptomycin Is More Active than Daptomycin or Exebacase Alone in Methicillin-Resistant Staphylococcus aureus Osteomyelitis in Rats

在耐甲氧西林金黄色葡萄球菌性大鼠骨髓炎中，Exebacase 与达托霉素联合使用比单独使用达托霉素或 Exebacase 更有效。

期刊:Antimicrobial Agents and Chemotherapy
影响因子:4.5
doi:10.1128/AAC.01235-19
Karau, Melissa J; Schmidt-Malan, Suzannah M; Yan, Qun; Greenwood-Quaintance, Kerryl E; Mandrekar, Jayawant; Lehoux, Dario; Schuch, Raymond; Cassino, Cara; Patel, Robin
Rat
骨髓炎
发表日期：2019
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Oritavancin Pharmacokinetics and Bone Penetration in Rabbits

奥利万星在兔体内的药代动力学和骨渗透性

期刊:Antimicrobial Agents and Chemotherapy
影响因子:4.5
doi:10.1128/AAC.00981-15
Lehoux, Dario; Ostiguy, Valerie; Cadieux, Cordelia; Malouin, Mireille; Belanger, Odette; Far, Adel Rafai; Parr, Thomas R Jr
Rabbit
发表日期：2015
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