日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

FACT weakens the nucleosomal barrier to transcription and preserves its integrity by forming a hexasome-like intermediate.

FACT 通过形成六聚体样中间体来削弱核小体对转录的屏障并保持其完整性

Burgos-Bravo Francesca, Tong Alexander B, Li Chen, Díaz-Celis César, Kaplan Craig D, LeRoy Gary, Reinberg Danny, Bustamante Carlos

Integrator promotes the association of TFIID and RNA polymerase II to maintain pluripotency during development.

整合酶促进 TFIID 和 RNA 聚合酶 II 的结合,以在发育过程中维持多能性

Edupuganti Raghu Ram, Beckedorff Felipe, Cingaram Pradeep Kumar Reddy, Parast Saeid Mohammad, Yue Jingyin, LeRoy Gary, Valencia Monica Guiselle, Dokaneheifard Sadat, Gomes Dos Santos Helena, Ocejo Omar Lopez, Xu Mingjiang, DeRosa Brooke A, Dykxhoorn Derek M, Lavezzo Guilherme Miura, Bilbao Daniel, Reinberg Danny, Morey Lluis, Shilatifard Ali, Shiekhattar Ramin

An Esrrb and Nanog Cell Fate Regulatory Module Controlled by Feed Forward Loop Interactions

由前馈回路相互作用控制的Esrrb和Nanog细胞命运调控模块

Sevilla, Ana; Papatsenko, Dimitri; Mazloom, Amin R; Xu, Huilei; Vasileva, Ana; Unwin, Richard D; LeRoy, Gary; Chen, Edward Y; Garrett-Bakelman, Francine E; Lee, Dung-Fang; Trinite, Benjamin; Webb, Ryan L; Wang, Zichen; Su, Jie; Gingold, Julian; Melnick, Ari; Garcia, Benjamin A; Whetton, Anthony D; MacArthur, Ben D; Ma'ayan, Avi; Lemischka, Ihor R

Low-Grade Astrocytoma Mutations in IDH1, P53, and ATRX Cooperate to Block Differentiation of Human Neural Stem Cells via Repression of SOX2

低级别星形细胞瘤中IDH1、P53和ATRX的突变协同作用,通过抑制SOX2阻断人类神经干细胞的分化。

Modrek, Aram S; Golub, Danielle; Khan, Themasap; Bready, Devin; Prado, Jod; Bowman, Christopher; Deng, Jingjing; Zhang, Guoan; Rocha, Pedro P; Raviram, Ramya; Lazaris, Charalampos; Stafford, James M; LeRoy, Gary; Kader, Michael; Dhaliwal, Joravar; Bayin, N Sumru; Frenster, Joshua D; Serrano, Jonathan; Chiriboga, Luis; Baitalmal, Rabaa; Nanjangud, Gouri; Chi, Andrew S; Golfinos, John G; Wang, Jing; Karajannis, Matthias A; Bonneau, Richard A; Reinberg, Danny; Tsirigos, Aristotelis; Zagzag, David; Snuderl, Matija; Skok, Jane A; Neubert, Thomas A; Placantonakis, Dimitris G

Proteogenomics analysis reveals specific genomic orientations of distal regulatory regions composed by non-canonical histone variants

蛋白质基因组学分析揭示了由非经典组蛋白变体组成的远端调控区域的特定基因组方向

Won, Kyoung-Jae; Choi, Inchan; LeRoy, Gary; Zee, Barry M; Sidoli, Simone; Gonzales-Cope, Michelle; Garcia, Benjamin A

Multi-faceted quantitative proteomics analysis of histone H2B isoforms and their modifications

组蛋白H2B亚型及其修饰的多方面定量蛋白质组学分析

Molden, Rosalynn C; Bhanu, Natarajan V; LeRoy, Gary; Arnaudo, Anna M; Garcia, Benjamin A

Tyr26 phosphorylation of PGAM1 provides a metabolic advantage to tumours by stabilizing the active conformation

PGAM1 的 Tyr26 位点磷酸化通过稳定其活性构象,为肿瘤提供代谢优势。

Hitosugi, Taro; Zhou, Lu; Fan, Jun; Elf, Shannon; Zhang, Liang; Xie, Jianxin; Wang, Yi; Gu, Ting-Lei; Alečković, Masa; LeRoy, Gary; Kang, Yibin; Kang, Hee-Bum; Seo, Jae-Ho; Shan, Changliang; Jin, Peng; Gong, Weimin; Lonial, Sagar; Arellano, Martha L; Khoury, Hanna J; Chen, Georgia Z; Shin, Dong M; Khuri, Fadlo R; Boggon, Titus J; Kang, Sumin; He, Chuan; Chen, Jing

A quantitative atlas of histone modification signatures from human cancer cells

人类癌细胞组蛋白修饰特征的定量图谱

Leroy, Gary; Dimaggio, Peter A; Chan, Eric Y; Zee, Barry M; Blanco, M Andres; Bryant, Barbara; Flaniken, Ian Z; Liu, Sherry; Kang, Yibin; Trojer, Patrick; Garcia, Benjamin A

Global secretome analysis identifies novel mediators of bone metastasis

全球分泌组分析揭示骨转移的新介质

Blanco, Mario Andres; LeRoy, Gary; Khan, Zia; Alečković, Maša; Zee, Barry M; Garcia, Benjamin A; Kang, Yibin

Quantitative proteomics reveals direct and indirect alterations in the histone code following methyltransferase knockdown

定量蛋白质组学揭示了甲基转移酶敲低后组蛋白密码的直接和间接改变

Plazas-Mayorca, Mariana D; Bloom, Joshua S; Zeissler, Ulrike; Leroy, Gary; Young, Nicolas L; DiMaggio, Peter A; Krugylak, Leonid; Schneider, Robert; Garcia, Benjamin A