日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The Candida albicans transcription factor Cas5 couples stress responses, drug resistance and cell cycle regulation.

白色念珠菌转录因子 Cas5 将应激反应、耐药性和细胞周期调控联系起来

Xie Jinglin L, Qin Longguang, Miao Zhengqiang, Grys Ben T, Diaz Jacinto De La Cruz, Ting Kenneth, Krieger Jonathan R, Tong Jiefei, Tan Kaeling, Leach Michelle D, Ketela Troy, Moran Michael F, Krysan Damian J, Boone Charles, Andrews Brenda J, Selmecki Anna, Ho Wong Koon, Robbins Nicole, Cowen Leah E

Opportunistic yeast pathogens: reservoirs, virulence mechanisms, and therapeutic strategies

机会性酵母病原体:储存库、毒力机制和治疗策略

Polvi, Elizabeth J; Li, Xinliu; O'Meara, Teresa R; Leach, Michelle D; Cowen, Leah E

Functional Divergence of Hsp90 Genetic Interactions in Biofilm and Planktonic Cellular States.

生物膜和浮游细胞状态下 Hsp90 基因相互作用的功能差异

Diezmann Stephanie, Leach Michelle D, Cowen Leah E

Stress adaptation in a pathogenic fungus

致病真菌的应激适应

Brown, Alistair J P; Budge, Susan; Kaloriti, Despoina; Tillmann, Anna; Jacobsen, Mette D; Yin, Zhikang; Ene, Iuliana V; Bohovych, Iryna; Sandai, Doblin; Kastora, Stavroula; Potrykus, Joanna; Ballou, Elizabeth R; Childers, Delma S; Shahana, Shahida; Leach, Michelle D

Membrane fluidity and temperature sensing are coupled via circuitry comprised of Ole1, Rsp5, and Hsf1 in Candida albicans

白色念珠菌中,膜流动性和温度感知是通过由 Ole1、Rsp5 和 Hsf1 组成的回路耦合的。

Leach, Michelle D; Cowen, Leah E

Surviving the heat of the moment: a fungal pathogens perspective

化险为夷:真菌病原体的视角

Leach, Michelle D; Cowen, Leah E

Fungal Hsp90: a biological transistor that tunes cellular outputs to thermal inputs

真菌Hsp90:一种生物晶体管,可根据热输入调节细胞输出

Leach, Michelle D; Klipp, Edda; Cowen, Leah E; Brown, Alistair J P

The evolutionary rewiring of ubiquitination targets has reprogrammed the regulation of carbon assimilation in the pathogenic yeast Candida albicans

泛素化靶标的进化重塑改变了致病酵母白色念珠菌的碳同化调控。

Sandai, Doblin; Yin, Zhikang; Selway, Laura; Stead, David; Walker, Janet; Leach, Michelle D; Bohovych, Iryna; Ene, Iuliana V; Kastora, Stavroula; Budge, Susan; Munro, Carol A; Odds, Frank C; Gow, Neil A R; Brown, Alistair J P

Modelling the regulation of thermal adaptation in Candida albicans, a major fungal pathogen of humans.

对人类主要真菌病原体——白色念珠菌的热适应调控进行建模

Leach Michelle D, Tyc Katarzyna M, Brown Alistair J P, Klipp Edda

Posttranslational modifications of proteins in the pathobiology of medically relevant fungi

医学相关真菌病理生物学中蛋白质的翻译后修饰

Leach, Michelle D; Brown, Alistair J P