日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

High-throughput discovery of transmembrane helix dimers from human single-pass membrane proteins with TOXGREEN sort-seq

利用TOXGREEN sort-seq技术对人类单次跨膜蛋白中的跨膜螺旋二聚体进行高通量发现

Anderson, Samantha M; Choi, Joshua; Cushman, Emma M; Leander, Megan; Raman, Srivatsan; Senes, Alessandro

High-throughput discovery of transmembrane helix dimers from human single-pass membrane proteins with TOXGREEN sort-seq.

利用 TOXGREEN sort-seq 技术从人类单次跨膜蛋白中高通量发现跨膜螺旋二聚体

Anderson Samantha M, Choi Joshua, Cushman Emma M, Leander Megan, Raman Srivatsan, Senes Alessandro

Deep mutational scanning and machine learning reveal structural and molecular rules governing allosteric hotspots in homologous proteins

深度突变扫描和机器学习揭示了同源蛋白中变构热点的结构和分子规律

Leander, Megan; Liu, Zhuang; Cui, Qiang; Raman, Srivatsan

Cardiac contractility structure-activity relationship and ligand-receptor interactions; the discovery of unique and novel molecular switches in myosuppressin signaling

心脏收缩力结构-活性关系和配体-受体相互作用;肌抑制素信号传导中独特和新型分子开关的发现

Leander, Megan; Bass, Chloe; Marchetti, Kathryn; Maynard, Benjamin F; Wulff, Juan Pedro; Ons, Sheila; Nichols, Ruthann

Structure-activity relationships of FMRF-NH2 peptides demonstrate A role for the conserved C terminus and unique N-terminal extension in modulating cardiac contractility

FMRF-NH2肽的结构-活性关系表明,保守的C端和独特的N端延伸在调节心脏收缩力中发挥作用。

Maynard, Benjamin F; Bass, Chloe; Katanski, Chris; Thakur, Kiran; Manoogian, Beth; Leander, Megan; Nichols, Ruthann