日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Unveiling Diagnostic Biomarkers in Autism: A Comparative Proteome Analysis of CNTNAP2 Knockout Mice and Human ASD Patients

揭示自闭症的诊断生物标志物：CNTNAP2基因敲除小鼠与人类自闭症谱系障碍患者的比较蛋白质组学分析

期刊:Biomolecules
影响因子:4.8
doi:10.3390/biom16030340
Kim, Andrew; Cho, Ara; Kim, Jiyeon; Sayson, Leandro Val; Lee, Hyun Ju; Cheong, Jae Hoon; Kim, Hee Jin; Kim, Bung Nyun; Yi, Eugene C
Human
自闭症
神经科学
发表日期：2026
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Unraveling Predominantly Inattentive ADHD (ADHD-PI): Insights from Proteomic Analysis of the Striatum of Thyroid Hormone-Responsive Protein (THRSP)-Overexpressing Mice

揭示以注意力缺陷为主的注意力缺陷多动障碍（ADHD-PI）：来自甲状腺激素反应蛋白（THRSP）过表达小鼠纹状体蛋白质组学分析的启示

期刊:Molecular Neurobiology
影响因子:4.3
doi:10.1007/s12035-025-05031-z
Custodio, Raly James Perez; Sayson, Leandro Val; Cho, Ara; Jung, Hyeryeon; Ortiz, Darlene Mae; Lee, Hyun Jun; Alyan, Emad; Wascher, Edmund; Getzmann, Stephan; Kim, Mikyung; Kim, Kyeong-Man; Yi, Eugene C; Kim, Hee Jin; Cheong, Jae Hoon
HRS
免疫/内分泌
发表日期：2025
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Impact and Interrelationships of Striatal Proteins, EPHB2, OPRM1, and PER2 on Mild Cognitive Impairment.

纹状体蛋白EPHB2、OPRM1和PER2对轻度认知障碍的影响及相互关系

期刊:Molecular Neurobiology
影响因子:4.3
doi:10.1007/s12035-024-04334-x
Campomayor Nicole Bon, Kim Hee Jin, Lee Hyun Jun, Sayson Leandro Val, Ortiz Darlene Mae D, Cho Eunbi, Kim Dong Hyun, Jeon Se Jin, Kim Bung-Nyun, Cheong Jae Hoon, Kim Mikyung
信号转导
EPHB2
EphB2
发表日期：2025
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Ameliorating effects of Acanthopanax koreanum extract and components on nicotine dependence and withdrawal symptoms

朝鲜刺五加提取物及其成分对尼古丁依赖及戒断症状的改善作用

期刊:Addiction Biology
影响因子:3.1
doi:10.1111/adb.13360
Hyun Jun Lee, Darlene Mae Ortiz, Leandro Val Sayson, Mikyung Kim, Jae Hoon Cheong, Hee Jin Kim
发表日期：2024
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Korean Red Ginseng extract attenuates alcohol-induced addictive responses and cognitive impairments by alleviating neuroinflammation

韩国红参提取物可通过缓解神经炎症来减轻酒精引起的成瘾反应和认知障碍

期刊:Journal of Ginseng Research
影响因子:6.8
doi:10.1016/j.jgr.2023.02.003
Hee Jin Kim, Min Yeong Lee, Gyu Ri Kim, Hyun Jun Lee, Leandro Val Sayson, Darlene Mae D Ortiz, Jae Hoon Cheong, Mikyung Kim
免疫
神经
神经炎症
WB
发表日期：2023
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Hippocampal dentate gyri proteomics reveals Wnt signaling involvement in the behavioral impairment in the THRSP-overexpressing ADHD mouse model

海马齿状回蛋白质组学揭示 Wnt 信号与 THRSP 过度表达 ADHD 小鼠模型中的行为障碍有关

期刊:Communications Biology
影响因子:5.2
doi:10.1038/s42003-022-04387-5
Raly James Perez Custodio #, Hee Jin Kim #, Jiyeon Kim, Darlene Mae Ortiz, Mikyung Kim, Danilo Buctot, Leandro Val Sayson, Hyun Jun Lee, Bung-Nyun Kim, Eugene C Yi, Jae Hoon Cheong
信号转导
GPCR/Calcium/cAMP
Wnt/β-Catenin
Mouse
发表日期：2023
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Deletion of Cryab increases the vulnerability of mice to the addiction-like effects of the cannabinoid JWH-018 via upregulation of striatal NF-κB expression

删除 Cryab 会增加小鼠对大麻素 JWH-018 成瘾样效应的易感性，这是通过上调纹状体 NF-κB 表达实现的

期刊:Frontiers in Pharmacology
影响因子:4.4
doi:10.3389/fphar.2023.1135929
Leandro Val Sayson, Darlene Mae Ortiz, Hyun Jun Lee, Mikyung Kim, Raly James Perez Custodio, Jaesuk Yun, Chae Hyeon Lee, Yong Sup Lee, Hye Jin Cha, Jae Hoon Cheong, Hee Jin Kim
信号转导
NF-κB
发表日期：2023
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4-F-PCP, a Novel PCP Analog Ameliorates the Depressive-Like Behavior of Chronic Social Defeat Stress Mice via NMDA Receptor Antagonism

4-F-PCP，一种新型 PCP 类似物，通过 NMDA 受体拮抗作用改善慢性社交挫败应激小鼠的抑郁样行为

期刊:Biomolecules & Therapeutics
影响因子:
doi:10.4062/biomolther.2022.159
Darlene Mae D Ortiz, Mikyung Kim, Hyun Jun Lee, Chrislean Jun Botanas, Raly James Perez Custodio, Leandro Val Sayson, Nicole Bon Campomayor, Chaeyeon Lee, Yong Sup Lee, Jae Hoon Cheong, Hee Jin Kim
神经
抑郁症
发表日期：2023
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Differentially Expressed Genes in Period 2-Overexpressing Mice Striatum May Underlie Their Lower Sensitivity to Methamphetamine Addiction-Like Behavior

在第二阶段过表达小鼠纹状体中差异表达的基因可能是其对甲基苯丙胺成瘾样行为敏感性较低的潜在原因

期刊:Biomolecules & Therapeutics
影响因子:3.2
doi:10.4062/biomolther.2021.184
Sayson, Leandro Val; Kim, Mikyung; Jeon, Se Jin; Custodio, Raly James Perez; Lee, Hyun Jun; Ortiz, Darlene Mae; Cheong, Jae Hoon; Kim, Hee Jin
发表日期：2022
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Low striatal T3 is implicated in inattention and memory impairment in an ADHD mouse model overexpressing thyroid hormone-responsive protein

在过度表达甲状腺激素反应蛋白的 ADHD 小鼠模型中，纹状体 T3 水平低与注意力不集中和记忆力受损有关

期刊:Communications Biology
影响因子:5.2
doi:10.1038/s42003-021-02633-w
Raly James Perez Custodio, Mikyung Kim, Leandro Val Sayson, Hyun Jun Lee, Darlene Mae Ortiz, Bung-Nyun Kim, Hee Jin Kim, Jae Hoon Cheong
信号转导
Mouse
发表日期：2021
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