日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Murine thrombus organization limits access to high platelet activation states while supporting platelet recruitment

小鼠血栓的组织结构限制了血小板进入高活化状态,同时促进血小板募集。

Rhee, Sung W; Pokrovskaya, Irina D; Ball, Kelly K; Webb, Michael W; Kamykowski, Jeffrey A; Aronova, Maria A; Leapman, Richard D; Driehaus, Elizabeth R; Franz, Erich S; Whiteheart, Sidney W; Storrie, Brian

Study on Liver Sinusoidal Endothelial Cell Fenestrations Based on Cellular Omics-Structure Integration Technology and Its Application in Metabolic Diseases

基于细胞组学-结构整合技术的肝窦内皮细胞窗孔研究及其在代谢性疾病中的应用

Wei, Zhuang; Chen, Jiji; Leapman, Richard D

Densely Populated Cell and Organelles Segmentation with U-Net Ensembles

利用 U-Net 集成进行密集细胞和细胞器分割

Fulton, Samuel J; Baenen, Cameron M; Storrie, Brian; Yang, Zijie; Leapman, Richard D; Aronova, Maria A

Evolution of a fuzzy ribonucleoprotein complex in viral assembly.

病毒组装过程中模糊核糖核蛋白复合物的演化

Zhao Huaying, Li Tiansheng, Hassan Sergio A, Nguyen Ai, Datta Siddhartha A K, Zhang Guofeng, Trent Camden, Czaja Agata M, Wu Di, Aronova Maria A, Lai Kin Kui, Piszczek Grzegorz, Leapman Richard D, Yewdell Jonathan W, Schuck Peter

Tethered platelet capture provides a mechanism for restricting circulating platelet activation to the wound site

束缚血小板捕获提供了一种将循环血小板活化限制在伤口部位的机制。

Pokrovskaya, Irina D; Rhee, Sung W; Ball, Kelly K; Kamykowski, Jeffrey A; Zhao, Oliver S; Cruz, Denzel R D; Cohen, Joshua; Aronova, Maria A; Leapman, Richard D; Storrie, Brian

Deep learning, 3D ultrastructural analysis reveals quantitative differences in platelet and organelle packing in COVID-19/SARSCoV2 patient-derived platelets.

深度学习 3D 超微结构分析揭示了 COVID-19/SARSCoV2 患者血小板中血小板和细胞器排列的定量差异

Matharu Sagar S, Nordmann Cassidy S, Ottman Kurtis R, Akkem Rahul, Palumbo Douglas, Cruz Denzel R D, Campbell Kenneth, Sievert Gail, Sturgill Jamie, Porterfield James Z, Joshi Smita, Alfar Hammodah R, Peng Chi, Pokrovskaya Irina D, Kamykowski Jeffrey A, Wood Jeremy P, Garvy Beth, Aronova Maria A, Whiteheart Sidney W, Leapman Richard D, Storrie Brian

Palmitoylation of A-kinase anchoring protein 79/150 modulates its nanoscale organization, trafficking, and mobility in postsynaptic spines

A激酶锚定蛋白79/150的棕榈酰化作用调节其在突触后棘中的纳米级组织、运输和移动性。

Chen, Xiaobing; Crosby, Kevin C; Feng, Austin; Purkey, Alicia M; Aronova, Maria A; Winters, Christine A; Crocker, Virginia T; Leapman, Richard D; Reese, Thomas S; Dell'Acqua, Mark L

Venous puncture wound hemostasis results in a vaulted thrombus structured by locally nucleated platelet aggregates

静脉穿刺伤口止血后会形成由局部成核血小板聚集体构成的拱形血栓。

Rhee, Sung W; Pokrovskaya, Irina D; Ball, Kelly K; Ling, Kenny; Vedanaparti, Yajnesh; Cohen, Joshua; Cruz, Denzel R D; Zhao, Oliver S; Aronova, Maria A; Zhang, Guofeng; Kamykowski, Jeffrey A; Leapman, Richard D; Storrie, Brian

Canalicular system reorganization during mouse platelet activation as revealed by 3D ultrastructural analysis

三维超微结构分析揭示小鼠血小板活化过程中小管系统的重组

Pokrovskaya, Irina D; Tobin, Michael; Desai, Rohan; Joshi, Smita; Kamykowski, Jeffrey A; Zhang, Guofeng; Aronova, Maria A; Whiteheart, Sidney W; Leapman, Richard D; Storrie, Brian

Structural analysis of resting mouse platelets by 3D-EM reveals an unexpected variation in α-granule shape

利用三维电镜对静息小鼠血小板进行结构分析,揭示了α颗粒形状的意外变异。

Pokrovskaya, Irina; Tobin, Michael; Desai, Rohan; Aronova, Maria A; Kamykowski, Jeffrey A; Zhang, Guofeng; Joshi, Smita; Whiteheart, Sidney W; Leapman, Richard D; Storrie, Brian