日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Clinical efficacy of OS-01 peptide formulation in reducing the signs of periorbital skin aging

OS-01肽制剂在减轻眼周皮肤老化迹象方面的临床疗效

Zonari, Alessandra; Brace, Lear E; Li, Fanghua; Harder, Nathaniel H O; Harker, Claire; Jacob, Carolyn; Kaufman, Joely; Chilukuri, Suneel; Oliveira, Carolina R; Boroni, Mariana; Carvalho, Juliana L

OS-01 Peptide Topical Formulation Improves Skin Barrier Function and Reduces Systemic Inflammation Markers: A Pilot 12-Week Clinical Trial

OS-01肽外用制剂改善皮肤屏障功能并降低全身炎症标志物:一项为期12周的初步临床试验

Zonari, Alessandra; Brace, Lear E; Buhrer, Luiza Brunelli; Harder, Nathaniel H O; Harker, Claire; Aronson, Adam B; Tse, Caitlyn N; Oliveira, Carolina R; Boroni, Mariana; Carvalho, Juliana L

Author Correction: Senotherapeutic peptide treatment reduces biological age and senescence burden in human skin models

作者更正:Senotherapeutic 肽治疗可降低人类皮肤模型中的生物年龄和衰老负担

Zonari, Alessandra; Brace, Lear E; Al-Katib, Kallie; Porto, William F; Foyt, Daniel; Guiang, Mylieneth; Cruz, Edgar Andres Ochoa; Marshall, Bailey; Gentz, Melissa; Guimarães, Gabriela Rapozo; Franco, Octavio L; Oliveira, Carolina R; Boroni, Mariana; Carvalho, Juliana L

Senotherapeutic peptide treatment reduces biological age and senescence burden in human skin models

神经治疗肽治疗可降低人类皮肤模型中的生物年龄和衰老负担

Alessandra Zonari, Lear E Brace, Kallie Al-Katib, William F Porto, Daniel Foyt, Mylieneth Guiang, Edgar Andres Ochoa Cruz, Bailey Marshall, Melissa Gentz, Gabriela Rapozo Guimarães, Octavio L Franco, Carolina R Oliveira, Mariana Boroni, Juliana L Carvalho

Sulfur Amino Acid Supplementation Abrogates Protective Effects of Caloric Restriction for Enhancing Bone Marrow Regrowth Following Ionizing Radiation

含硫氨基酸补充剂可消除热量限制对电离辐射后增强骨髓再生的保护作用

Christopher Hine, J Humberto Treviño-Villarreal, Pedro Mejia, Alban Longchamp, Lear E Brace, Eylul Harputlugil, Sarah J Mitchell, Jie Yang, Yihong Guan, Jaroslaw P Maciejewski, Babal K Jha, James R Mitchell

Highly accurate skin-specific methylome analysis algorithm as a platform to screen and validate therapeutics for healthy aging

高度精确的皮肤特异性甲基化组分析算法作为筛选和验证健康衰老疗法的平台

Mariana Boroni, Alessandra Zonari, Carolina Reis de Oliveira, Kallie Alkatib, Edgar Andres Ochoa Cruz, Lear E Brace, Juliana Lott de Carvalho

Amino Acid Restriction Triggers Angiogenesis via GCN2/ATF4 Regulation of VEGF and H2S Production

氨基酸限制通过GCN2/ATF4调控VEGF和H2S的产生来触发血管生成。

Alban Longchamp ,Teodelinda Mirabella ,Alessandro Arduini ,Michael R MacArthur ,Abhirup Das ,J Humberto Treviño-Villarreal ,Christopher Hine ,Issam Ben-Sahra ,Nelson H Knudsen ,Lear E Brace ,Justin Reynolds ,Pedro Mejia ,Ming Tao ,Gaurav Sharma ,Rui Wang ,Jean-Marc Corpataux ,Jacques-Antoine Haefliger ,Kyo Han Ahn ,Chih-Hao Lee ,Brendan D Manning ,David A Sinclair ,Christopher S Chen ,C Keith Ozaki ,James R Mitchell

Dietary protein restriction reduces circulating VLDL triglyceride levels via CREBH-APOA5-dependent and -independent mechanisms

饮食蛋白质限制可通过 CREBH-APOA5 依赖性和非依赖性机制降低循环 VLDL 甘油三酯水平

J Humberto Treviño-Villarreal, Justin S Reynolds, Alexander Bartelt, P Kent Langston, Michael R MacArthur, Alessandro Arduini, Valeria Tosti, Nicola Veronese, Beatrice Bertozzi, Lear E Brace, Pedro Mejia, Kaspar Trocha, Gustavo S Kajitani, Alban Longchamp, Eylul Harputlugil, Rose Gathungu, Susan S B

Increased oxidative phosphorylation in response to acute and chronic DNA damage

急性和慢性 DNA 损伤导致氧化磷酸化增强

Lear E Brace, Sarah C Vose, Kristopher Stanya, Rose M Gathungu, Vasant R Marur, Alban Longchamp, Humberto Treviño-Villarreal, Pedro Mejia, Dorathy Vargas, Karen Inouye, Roderick T Bronson, Chih-Hao Lee, Edward Neilan, Bruce S Kristal, James R Mitchell

Defective mitophagy in XPA via PARP-1 hyperactivation and NAD(+)/SIRT1 reduction

XPA 中的线粒体自噬因 PARP-1 过度激活和 NAD(+)/SIRT1 减少而出现缺陷

Evandro Fei Fang #, Morten Scheibye-Knudsen #, Lear E Brace, Henok Kassahun, Tanima SenGupta, Hilde Nilsen, James R Mitchell, Deborah L Croteau, Vilhelm A Bohr