日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

An integrated analysis of three medulloblastoma clinical trials refines risk-stratification approaches for reducing toxicity and improving survival

对三项髓母细胞瘤临床试验的综合分析，改进了风险分层方法，以降低毒性并提高生存率。

期刊:Neuro-Oncology
影响因子:13.4
doi:10.1093/neuonc/noaf250
Smith, Kyle S; Dhanda, Sandeep K; Billups, Catherine A; Sioson, Edgar; Lu, Congyu; Peraza, Airen Zaldivar; Gangwani, Karishma; Li, Yimei; Li, Qian; Lin, Tong; Michalski, Jeff M; Packer, Roger J; Olson, James M; Leary, Sarah E S; Fouladi, Maryam; Gajjar, Amar; Zhou, Xin; Onar-Thomas, Arzu; Northcott, Paul A; Robinson, Giles W
细胞生物学
毒理研究
发表日期：2026
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Abstracts - IANCON 2025

摘要 - IANCON 2025

期刊:Neuro-Oncology
影响因子:13.4
doi:10.1093/neuonc/noaf064
Gust, Juliane; Cole, Bonnie L; Ronsley, Rebecca; Wilson, Ashley L; Seidel, Kristy; Wendler, Jason; Pattabhi, Sowmya; Brown, Christopher; Rawlings-Rhea, Stephanie D; Shtanukhina, Nadezhda; Browd, Samuel R; Hauptman, Jason S; Lee, Amy; Ojemann, Jeffrey G; Crotty, Erin E; Leary, Sarah E S; Perez, Francisco A; Wright, Jason N; Albert, Catherine M; Pinto, Navin; Gardner, Rebecca A; Vitanza, Nicholas A; Jensen, Michael C; Park, Julie R
发表日期：2026
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Interpretable trajectory inference with single-cell linear adaptive negative-binomial expression (scLANE) testing

利用单细胞线性自适应负二项式表达（scLANE）测试进行可解释的轨迹推断

期刊:Nucleic Acids Research
影响因子:13.1
doi:10.1093/nar/gkaf1494
Leary, Jack R; Dong, Xiaoru; Bacher, Rhonda
细胞生物学
单细胞
发表日期：2026
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Harnessing metabolomics and proteomics in a clinical trial for pulmonary arterial hypertension: insights from post-hoc analysis of the REHAB-PH trial

在肺动脉高压临床试验中应用代谢组学和蛋白质组学：来自 REHAB-PH 试验事后分析的启示

期刊:EBioMedicine
影响因子:10.8
doi:10.1016/j.ebiom.2026.106191
Pi, Hongyang; Xia, Lu; Rayner, Samuel G; Probstfield, Jeffrey L; Branch, Kelley R; Shojaie, Ali; Leary, Peter J; Gharib, Sina A
肺动脉高压
心血管
代谢
发表日期：2026
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zAvatar-test-A functional precision model to personalize ovarian cancer treatments: Results from a co-clinical study.

zAvatar-test-用于个性化卵巢癌治疗的功能性精确模型：一项联合临床研究的结果。

期刊:Cell Reports Medicine
影响因子:10.6
doi:10.1016/j.xcrm.2025.102530
Estrada Marta F, Amorim Filipa, Ferreira da Silva Filipa, Rebelo de Almeida Cátia, Fontes Márcia, Coelho Ricardo, Ferreira Sónia, Canas-Marques Rita, Castillo-Martin Mireia, Casanova João, Batarda Maria de Lurdes, Yaniz-Galende Elisa, LeFormal Audrey, Marreiros Ana, Jacob Francis, Heinzelmann-Schwarz Viola, Leary Alexandra, Nabais Henrique, Fior Rita
卵巢癌
肿瘤
TES
发表日期：2026
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Genetically engineered ErbB2 overexpression sensitizes organoid-derived tumors to checkpoint inhibition in a syngeneic model of gastric cancer.

在同源胃癌模型中，基因工程改造的 ErbB2 过表达可使类器官衍生的肿瘤对检查点抑制剂更加敏感。

期刊:Journal for ImmunoTherapy of Cancer
影响因子:10.6
doi:10.1136/jitc-2025-012976
He Jiazhuo, Kirsche Lydia, Nascakova Zuzana, Manfredi Francesco, Magnani Chiara F, Papa Giovanni, Azizi Flora, Leary Peter, Müller Anne
胃癌
肿瘤
ERBB2
Checkpoint
3D/类器官
发表日期：2026
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Childhood cancer data initiative: expanded access to tumor molecular profiling for children, adolescents, and young adults

儿童癌症数据计划：扩大儿童、青少年和年轻成人肿瘤分子谱分析的获取途径

期刊:Jnci-Journal of the National Cancer Institute
影响因子:7.2
doi:10.1093/jnci/djaf214
Flores-Toro, Joseph; Jagu, Subhashini; Smith, Malcolm; Shern, John; Hawkins, Douglas S; Mardis, Elaine R; Rudzinski, Erin; Alonzo, Todd A; Beeles, Thalia; Ramirez, Nilsa; Thomas, Diana L; Cottrell, Catherine E; Parbhoo, Kareesma; Janeway, Katherine A; Leary, Sarah; Fouladi, Maryam; Oberoi, Sapna; Venkatramani, Rajkumar; Irwin, Meredith; Laetsch, Theodore W; Chen, Kenneth S; Bailey, Kelly; Davis, Jessica L; Sullivan, Mary Beth; Boja, Emily; Lowy, Douglas; Guidry Auvil, Jaime M; Wideman, Brigitte; Kibbe, Warren; Doroshow, James; Reaman, Gregory H
肿瘤
肿瘤免疫
发表日期：2026
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TGF-β Regulates CD8(+) T Cell Memory by Triggering mTORC1(Weak)-Mediated Activation of the Transcriptional FOXO1-TCF1-Eomes and Metabolic AMPK-ULK1-ATG7 Pathways

TGF-β通过触发mTORC1(弱)介导的转录FOXO1-TCF1-Eomes通路和代谢AMPK-ULK1-ATG7通路激活来调节CD8(+) T细胞记忆

期刊:Cells
影响因子:5.2
doi:10.3390/cells15050471
Wu, Zhaojia; Yu, Michelle; Leary, Scot C; Yuan, Jianbo; Huang, Junqiong; Xiang, Jim
mTOR
T细胞
TGF-β
信号转导
ULK1
AMPK
CD8
代谢
ATG7
FOXO1
T细胞
ORC1
细胞生物学
免疫/内分泌
发表日期：2026
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Gut microbial signatures expose the westernized lifestyle of urban Ethiopian children

肠道微生物特征揭示了埃塞俄比亚城市儿童的西式生活方式

期刊:Communications Biology
影响因子:5.1
doi:10.1038/s42003-026-09639-2
Kirsche, Lydia; Leary, Peter; Blaser, Martin J; Scharl, Michael; Negussie, Adugna; Müller, Anne
微生物学
发表日期：2026
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Hatching method correlates to early growth in chickens but not later performance

孵化方式与鸡的早期生长相关，但与后期性能无关。

期刊:Poultry Science
影响因子:4.2
doi:10.1016/j.psj.2026.106478
Xie, Carria; Macelline, Shemil P; Melwani, Robin R; Toghyani, Mehdi; Leary, Alison; Liu, Sonia Y
发表日期：2026
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