日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Impact of an SLC30A8 loss-of-function variant on the pancreatic distribution of zinc and manganese: laser ablation-ICP-MS and positron emission tomography studies in mice

SLC30A8功能缺失变异对小鼠胰腺中锌和锰分布的影响:激光烧蚀-电感耦合等离子体质谱和正电子发射断层扫描研究

Firth, George; Georgiadou, Eleni; Griffiths, Alexander; Amrahli, Maral; Kim, Jana; Yu, Zilin; Hu, Ming; Stewart, Theodora J; Leclerc, Isabelle; Okamoto, Haruka; Gomez, Daniel; Blower, Philip J; Rutter, Guy A

Chronic noncancer pain management: Integration of a nurse-led program in primary care

慢性非癌性疼痛管理:将护士主导的项目整合到初级保健中

Assefa, Metasebia; LeClerc, Isabelle; Muggah, Elizabeth; Deonandan, Raywat; Godbout, Charles; Finestone, Hillel M

Mitofusins Mfn1 and Mfn2 Are Required to Preserve Glucose- but Not Incretin-Stimulated β-Cell Connectivity and Insulin Secretion

线粒体融合蛋白Mfn1和Mfn2是维持葡萄糖刺激的β细胞连接和胰岛素分泌所必需的,但并非肠促胰岛素刺激的β细胞连接和胰岛素分泌所必需的。

Georgiadou, Eleni; Muralidharan, Charanya; Martinez, Michelle; Chabosseau, Pauline; Akalestou, Elina; Tomas, Alejandra; Wern, Fiona Yong Su; Stylianides, Theodoros; Wretlind, Asger; Legido-Quigley, Cristina; Jones, Ben; Lopez-Noriega, Livia; Xu, Yanwen; Gu, Guoqiang; Alsabeeh, Nour; Cruciani-Guglielmacci, Céline; Magnan, Christophe; Ibberson, Mark; Leclerc, Isabelle; Ali, Yusuf; Soleimanpour, Scott A; Linnemann, Amelia K; Rodriguez, Tristan A; Rutter, Guy A

Vertical sleeve gastrectomy normalizes circulating glucocorticoid levels and lowers glucocorticoid action tissue-selectively in mice

垂直袖状胃切除术可使小鼠循环糖皮质激素水平恢复正常,并有组织选择性地降低糖皮质激素的作用。

Akalestou, Elina; Lopez-Noriega, Livia; Christakis, Ioannis; Hu, Ming; Miras, Alexander D; Leclerc, Isabelle; Rutter, Guy A

Author Correction: Intravital imaging of islet Ca(2+) dynamics reveals enhanced β cell connectivity after bariatric surgery in mice

作者更正:小鼠减重手术后胰岛Ca(2+)动态的活体成像显示β细胞连接性增强

Akalestou, Elina; Suba, Kinga; Lopez-Noriega, Livia; Georgiadou, Eleni; Chabosseau, Pauline; Gallie, Alasdair; Wretlind, Asger; Legido-Quigley, Cristina; Leclerc, Isabelle; Salem, Victoria; Rutter, Guy A

Intravital imaging of islet Ca(2+) dynamics reveals enhanced β cell connectivity after bariatric surgery in mice

小鼠减重手术后胰岛Ca(2+)动态的活体成像显示β细胞连接性增强。

Akalestou, Elina; Suba, Kinga; Lopez-Noriega, Livia; Georgiadou, Eleni; Chabosseau, Pauline; Gallie, Alasdair; Wretlind, Asger; Legido-Quigley, Cristina; Leclerc, Isabelle; Salem, Victoria; Rutter, Guy A

Synthesis and in vivo behaviour of an exendin-4-based MRI probe capable of β-cell-dependent contrast enhancement in the pancreas

基于艾塞那肽-4的MRI探针的合成及其在胰腺中β细胞依赖性对比增强的体内行为

Clough, Thomas J; Baxan, Nicoleta; Coakley, Emma J; Rivas, Charlotte; Zhao, Lan; Leclerc, Isabelle; Martinez-Sanchez, Aida; Rutter, Guy A; Long, Nicholas J

Leader β-cells coordinate Ca(2+) dynamics across pancreatic islets in vivo.

体内胰岛中,领头β细胞协调Ca(2+)动态

Salem Victoria, Silva Luis Delgadillo, Suba Kinga, Georgiadou Eleni, Neda Mousavy Gharavy S, Akhtar Nadeem, Martin-Alonso Aldara, Gaboriau David C A, Rothery Stephen M, Stylianides Theodoros, Carrat Gaelle, Pullen Timothy J, Singh Sumeet Pal, Hodson David J, Leclerc Isabelle, Shapiro A M James, Marchetti Piero, Briant Linford J B, Distaso Walter, Ninov Nikolay, Rutter Guy A

Correction: Transcription factor-7-like 2 (TCF7L2) gene acts downstream of the Lkb1/Stk11 kinase to control mTOR signaling, β cell growth, and insulin secretion

更正:转录因子7样2 (TCF7L2) 基因位于Lkb1/Stk11激酶的下游,控制mTOR信号传导、β细胞生长和胰岛素分泌。

Nguyen-Tu, Marie-Sophie; da Silva Xavier, Gabriela; Leclerc, Isabelle; Rutter, Guy A

Decreased STARD10 Expression Is Associated with Defective Insulin Secretion in Humans and Mice

STARD10表达降低与人类和小鼠胰岛素分泌缺陷相关

Carrat, Gaelle R; Hu, Ming; Nguyen-Tu, Marie-Sophie; Chabosseau, Pauline; Gaulton, Kyle J; van de Bunt, Martijn; Siddiq, Afshan; Falchi, Mario; Thurner, Matthias; Canouil, Mickaël; Pattou, Francois; Leclerc, Isabelle; Pullen, Timothy J; Cane, Matthew C; Prabhala, Priyanka; Greenwald, William; Schulte, Anke; Marchetti, Piero; Ibberson, Mark; MacDonald, Patrick E; Manning Fox, Jocelyn E; Gloyn, Anna L; Froguel, Philippe; Solimena, Michele; McCarthy, Mark I; Rutter, Guy A