日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Pain relief by targeting nonrestorative sleep in fibromyalgia: a phase 3 randomized trial of bedtime sublingual cyclobenzaprine

通过改善非恢复性睡眠来缓解纤维肌痛疼痛：一项睡前舌下含服环苯扎林的3期随机试验

期刊:Pain Medicine
影响因子:3
doi:10.1093/pm/pnaf089
Lederman, Seth; Arnold, Lesley M; Vaughn, Ben; Engels, Jean M; Kelley, Mary; Sullivan, Gregory M
纤维肌痛综合征
发表日期：2026
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Single-Dose Pharmacokinetic Assessment of TNX-102 SL (Cyclobenzaprine HCl Sublingual Tablets): Results From Randomized, Open-Label Studies in Healthy Volunteers

TNX-102 SL（盐酸环苯扎林舌下片）单剂量药代动力学评估：来自健康志愿者随机、开放标签研究的结果

期刊:Clinical Pharmacology in Drug Development
影响因子:1.8
doi:10.1002/cpdd.70034
Daugherty, Bruce L; Meibohm, Bernd; Sullivan, Gregory M; Gould, Errol M; Lederman, Seth
发表日期：2026
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Steady-State Pharmacokinetic Properties of TNX-102 SL, a Sublingual Tablet Formulation of Cyclobenzaprine Hydrochloride (HCl), With Daily Dosing in Healthy Volunteers: A Randomized, Open-Label Trial

TNX-102 SL（盐酸环苯扎林舌下片）每日给药在健康志愿者中的稳态药代动力学特性：一项随机、开放标签试验

期刊:Clinical Pharmacology in Drug Development
影响因子:1.8
doi:10.1002/cpdd.70060
Sullivan, Gregory M; Meibohm, Bernd; Gould, Errol; Daugherty, Bruce L; Lederman, Seth
发表日期：2026
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Enhanced Costimulation Blockade With αCD154, αCD2, and αCD28 to Promote Heart Allograft Tolerance in Nonhuman Primates

利用αCD154、αCD2和αCD28增强共刺激阻断作用以促进非人灵长类动物心脏同种异体移植耐受性

期刊:Transplantation
影响因子:5
doi:10.1097/TP.0000000000005315
Chaban, Ryan; Ileka, Ikechukwu; Kinoshita, Kohei; McGrath, Gannon; Habibabady, Zahra; Ma, Madelyn; Diaz, Victoria; Maenaka, Akihiro; Rosales, Ivy; Lederman, Seth; Tkachev, Victor; Madsen, Joren C; Pierson, Richard N 3rd
CD15
CD2
CD28
Primate
发表日期：2025
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Extended survival of 9- and 10-gene-edited pig heart xenografts with ischemia minimization and CD154 costimulation blockade-based immunosuppression

通过减少缺血和基于 CD154 共刺激阻断的免疫抑制，延长了 9 个和 10 个基因编辑猪心脏异种移植的存活期

期刊:Journal of Heart and Lung Transplantation
影响因子:6
doi:10.1016/j.healun.2024.07.022
Chaban, Ryan; Ileka, Ikechukwu; McGrath, Gannon; Kinoshita, Kohei; Habibabady, Zahra; Ma, Madelyn; Diaz, Victoria; Maenaka, Akihiro; Calhoun, Anthony; Dufault, Megan; Rosales, Ivy; Laguerre, Christiana M; Sanatkar, Seyed-Amir; Burdorf, Lars; Ayares, David L; Eyestone, William; Sardana, Prachi; Kuravi, Kasinath; Sorrells, Lori; Lederman, Seth; Lucas, Caroline G; Prather, Randall S; Wells, Kevin D; Whitworth, Kristin M; Cooper, David K C; Pierson, Richard N 3rd
CD15
免疫/内分泌
发表日期：2024
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Chronic overlapping pain conditions increase the risk of long COVID features, regardless of acute COVID status

慢性重叠性疼痛疾病会增加出现新冠后遗症的风险，无论是否处于急性新冠状态。

期刊:Pain
影响因子:5.5
doi:10.1097/j.pain.0000000000003110
Bergmans, Rachel S; Clauw, Daniel J; Flint, Candace; Harris, Herb; Lederman, Seth; Schrepf, Andrew
微生物学
新冠
发表日期：2024
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High-Throughput Screening Assay for Convalescent Sera in COVID-19: Efficacy, Donor Selection, and Variant Neutralization

新冠肺炎康复者血清高通量筛选检测：有效性、供体选择和变异株中和

期刊:Microorganisms
影响因子:4.2
doi:10.3390/microorganisms12081503
Kota, Krishna P; Trakht, Ilya; Kalantarov, Gavreel; Ordonez, David; Wei, Jiayi; Trefry, Stephanie; Bavari, Evia; Richardson, Jenny; Zamani, Rouzbeh; Raney, Christy; Nasar, Farooq; Daugherty, Bruce; Lederman, Seth; Bavari, Sina
肺炎
新冠
微生物学
发表日期：2024
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Novel factors potentially initiating acute antibody-mediated rejection in pig kidney xenografts despite an efficient immunosuppressive regimen.

尽管采取了有效的免疫抑制方案，但仍存在可能引发猪肾异种移植急性抗体介导排斥反应的新因素。

期刊:Xenotransplantation
影响因子:4.1
doi:10.1111/xen.12859
Kinoshita Kohei, Maenaka Akihiro, Rosales Ivy A, Karadagi Ahmad, Tomosugi Toshihide, Ayares David, Lederman Seth, Colvin Robert B, Kawai Tatsuo, Pierson Richard N 3rd, Kobayashi Takaaki, Cooper David K C
免疫排斥
免疫/内分泌
发表日期：2024
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Recombinant chimeric horsepox virus (TNX-801) is attenuated relative to vaccinia virus strains in both in vitro and in vivo models

重组嵌合马痘病毒（TNX-801）在体外和体内模型中均比痘苗病毒株毒力减弱。

期刊:mSphere
影响因子:3.1
doi:10.1128/msphere.00265-24
Trefry, Stephanie V; Awasthi, Mayanka; Raney, Christy N; Cregger, Amy L; Gonzales, Chase A; Layton, Brittney L; Enamorado, Robert N; Martinez, Nelson A; Gohegan, Deborah S; Masoud-Bahnamiri, Masoudeh; Cho, Jennifer Y; Myscofski, Dawn M; Moulaei, Tinoush; Ziółkowska, Natasza E; Goebel, Scott J; Lederman, Seth; Bavari, Sina; Nasar, Farooq
微生物学
发表日期：2024
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TNX-1500, a crystallizable fragment-modified anti-CD154 antibody, prolongs nonhuman primate cardiac allograft survival

TNX-1500 是一种可结晶片段修饰的抗 CD154 抗体，可延长非人灵长类动物心脏同种异体移植的存活时间。

期刊:American Journal of Transplantation
影响因子:8.2
doi:10.1016/j.ajt.2023.03.025
Miura, Shuhei; Habibabady, Zahra A; Pollok, Franziska; Ma, Madelyn; Rosales, Ivy A; Kinoshita, Kohei; Pratts, Shannon; McGrath, Gannon; Chaban, Ryan; Fogarty, Siobhan; Meibohm, Bernd; Daugherty, Bruce; Lederman, Seth; Pierson, Richard N 3rd
CD15
发表日期：2023
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