日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Discovery and cryoEM structure of FPM13, a periplasmic metalloprotein unique to Francisella

弗朗西斯菌特有的周质金属蛋白FPM13的发现及其冷冻电镜结构

Clemens, Daniel L; Lee, Bai-Yu; Liu, Xiaoyu; Zhou, Z Hong; Horwitz, Marcus A

Structure, identification, and characterization of the RibD-enolase complex in Francisella

弗朗西斯菌中 RibD-烯醇化酶复合物的结构、鉴定和表征

Liu, Xiaoyu; Clemens, Daniel L; Lee, Bai-Yu; Aguirre, Roman; Horwitz, Marcus A; Zhou, Z Hong

Adding Intranasal to Oral Administration of an Ultra-Rapid Near-Universal Drug Regimen Accelerates Relapse-Free Cure of Tuberculosis in Mice

在小鼠中,将鼻内给药与口服给药相结合,可加速结核病的无复发治愈。

Lee, Bai-Yu; Clemens, Daniel L; Masleša-Galic, Saša; Nava, Susana; Lo, Chiao-Yueh; Zink, Jeffrey I; Horwitz, Marcus A

Atomic Structure and Phospholipid Binding Properties of the Francisella Type VI Secretion System Effector Protein PdpC

弗朗西斯菌VI型分泌系统效应蛋白PdpC的原子结构和磷脂结合特性

Liu, Xiaoyu; Clemens, Daniel L; Lee, Bai-Yu; Xia, Xian; Fan, Hongcheng; Feng, Kaelyn Y; Horwitz, Marcus A; Zhou, Z Hong

Discovery and CryoEM Structure of FPM13, a Periplasmic Metalloprotein Unique to Francisella

弗朗西斯菌特有的周质金属蛋白FPM13的发现及冷冻电镜结构

Clemens, Daniel L; Lee, Bai-Yu; Liu, Xiaoyu; Zhou, Z Hong; Horwitz, Marcus A

Structure, identification and characterization of the RibD-enolase complex in Francisella.

弗朗西斯菌中 RibD-烯醇化酶复合物的结构、鉴定和表征

Liu Xiaoyu, Clemens Daniel L, Lee Bai-Yu, Aguirre Roman, Horwitz Marcus A, Zhou Z Hong

Efficacy and safety of an innovative short-course regimen containing clofazimine for treatment of drug-susceptible tuberculosis: a clinical trial

一项临床试验评估了含氯法齐明的创新型短程治疗方案治疗药物敏感性结核病的疗效和安全性。

Zheng, Xubin; Gui, Xuwei; Yao, Lan; Ma, Jun; He, Yifan; Lou, Hai; Gu, Jin; Ying, Ruoyan; Chen, Liping; Sun, Qin; Liu, Yidian; Ho, Chih-Ming; Lee, Bai-Yu; Clemens, Daniel L; Horwitz, Marcus A; Ding, Xianting; Hao, Xiaohui; Yang, Hua; Sha, Wei

AI-Enabled Parabolic Response Surface Approach Identifies Ultra Short-Course Near-Universal TB Drug Regimens

人工智能驱动的抛物线响应面法识别超短疗程近乎通用的结核病药物治疗方案

Christensen, Nikolaj R; Čalyševa, Jelena; Fernandes, Eduardo F A; Lüchow, Susanne; Clemmensen, Louise S; Haugaard-Kedström, Linda M; Strømgaard, Kristian; Horwitz, Marcus A; Clemens, Daniel L; Lee, Bai-Yu

The Francisella Type VI Secretion System

弗朗西斯菌VI型分泌系统

Clemens, Daniel L; Lee, Bai-Yu; Horwitz, Marcus A

Drug regimens identified and optimized by output-driven platform markedly reduce tuberculosis treatment time

通过结果导向平台识别和优化的药物方案可显著缩短结核病治疗时间

Lee, Bai-Yu; Clemens, Daniel L; Silva, Aleidy; Dillon, Barbara Jane; Masleša-Galić, Saša; Nava, Susana; Ding, Xianting; Ho, Chih-Ming; Horwitz, Marcus A