Lee Dae-Won相关文献与解析，生知库 | 链接生命科学的每一步

Park, Chan Soon; Ryu, Gangpyo; Ahn, Hyo-Jeong; Sun, Choonghyun; Lee, Seung-Pyo; Kim, Hyung-Kwan; Kim, Yong-Jin; Jeon, Sook Young; Lee, Han-Byoel; Moon, Hyeong-Gon; Han, Wonshik; Lee, Dae-Won; Lee, Kyung-Hun; Han, Sae-Won; Im, Seock-Ah; Lee, Sang Eun; Jaiswal, Siddhartha; Koh, Youngil; Park, Jun-Bean

毒理研究

发表日期：2026

文献求助收藏

DNA Damage and Nuclear Anaplasia Induced by Trastuzumab Deruxtecan in Cancer Cells with Variable HER2 Expression and Homologous Recombination Deficiency Status.

曲妥珠单抗德鲁替康在HER2表达和同源重组缺陷状态不同的癌细胞中诱导DNA损伤和核异型性。

期刊:Cancer Research and Treatment

影响因子:3.8

doi:10.4143/crt.2025.201

Kim So Hyeon, Park Yoonjung, Min Ahrum, Park Hye Yeon, Kim Yu-Jin, Ham Sujin, Koh Jiwon, Kim Seongyeong, Lee Dae-Won, Ryu Han Suk, Kim Jin-Soo, Lee Kyung-Hun, Im Seock-Ah

Elimusertib, a Novel ATR Inhibitor, Induces Anti-tumor Effects through Replication Catastrophe in Breast Cancers.

Elimusertib 是一种新型 ATR 抑制剂，可通过乳腺癌中的复制灾难诱导抗肿瘤作用。

期刊:Cancer Research and Treatment

影响因子:3.8

doi:10.4143/crt.2024.1105

Kim Mudong, Min Ahrum, Kim Sohyeon, Kim Seongyeong, Kim Yu-Jin, Ham Sujin, Lee Miso, Lee Eunice Yoojin, Kim Jinyong, Lee Dae-Won, Lee Kyung-Hun, Im Seock-Ah

Nationwide real-world practice pattern and clinical data of palbociclib in HR (+), HER2 (-) metastatic breast cancer patients in Korea (KCSG BR21-15)

韩国 HR (+)、HER2 (-) 转移性乳腺癌患者使用帕博西尼治疗的全国真实世界实践模式和临床数据 (KCSG BR21-15)

期刊:Breast

影响因子:7.9

doi:10.1016/j.breast.2025.104500

Lee, Jieun; Lee, Dae-Won; Kim, Min Hwan; Kim, Jee Hung; Kim, Ju Won; Byun, Jae-Ho; Lee, Kyoung Eun; Kang, Myoung Joo; Koh, Su-Jin; Hong, Soojung; Won, Hye Sung; Kim, Han Jo; Park, In Hae; Shin, Seong Hoon; Baek, Sun Kyung; Kim, Seul-Gi; Koh, Sung Ae; Jung, Joo Young; Kim, Ji-Yeon; Kim, Gun Min; Shin, Kabsoo; Woo, In Sook; Kim, Hyun Seon; Im, Seock-Ah; Park, Yeon Hee

Immunogenomic characteristics and prognostic implications of terminally exhausted CD8(+) T cells in colorectal cancers

结直肠癌中终末耗竭CD8(+) T细胞的免疫基因组特征及其预后意义

期刊:Frontiers in Immunology

影响因子:5.9

doi:10.3389/fimmu.2025.1601188

Lee, Ji-Ae; Park, Hye Eun; Lee, Dae-Won; Han, Sae-Won; Kim, Tae-You; Jeong, Seung-Yong; Park, Kyu Joo; Bae, Jeong Mo; Kang, Gyeong Hoon

MSN/STAT3 drives cancer stemness and chemoresistance via IL-6/LPAR1 ligand receptor complex in triple-negative breast cancer.

MSN/STAT3 通过 IL-6/LPAR1 配体受体复合物驱动三阴性乳腺癌的干性和化疗耐药性

期刊:Breast Cancer Research

影响因子:5.6

doi:10.1186/s13058-025-02072-z

Lee Cheng Hyun, Park Soo Young, Lee Jae Seok, Kim Da Sol, Kim Ha Yeon, Song Min Ji, Im Seock-Ah, Lee Kyung-Hun, Lee Dae-Won, Nikas Ilias P, Koh Ji Won, Yang So Hyeon, Lee Hyebin, Ryu Han Suk

Establishment and characterization of 24 breast cancer cell lines and 3 breast cancer organoids reveals molecular heterogeneity and drug response variability in malignant pleural effusion-derived models.

建立和表征 24 个乳腺癌细胞系和 3 个乳腺癌类器官，揭示了恶性胸腔积液衍生模型中的分子异质性和药物反应变异性

期刊:Breast Cancer Research

影响因子:5.6

doi:10.1186/s13058-025-02032-7

Kim Soon-Chan, Kim Ga-Hye, Park Jae-Hyeon, Lee Kyung-Hun, Koh Jiwon, Kim Tae-Yong, Lee Dae-Won, Kim Yu-Jin, Kim Seongyeong, Park Song-Yi, Min Ahrum, Shin Young-Kyoung, Im Seock-Ah, Ku Ja-Lok

Imaging lipid rafts reveals the principle of ApoE4-induced Aβ upregulation in human neurons

脂质筏成像揭示了 ApoE4 诱导人类神经元中 Aβ 上调的原理

期刊:iScience

影响因子:4.6

doi:10.1016/j.isci.2025.111893

Se-In Lee, Heejin Lim, Na Yeon Kim, Jichang Yu, Joonho Cho, Hyein Lee, Dae Won Moon, Jinsoo Seo

神经

发表日期：2025

文献求助收藏

Harnessing Institutionally Developed Clinical Targeted Sequencing to Improve Patient Survival in Breast Cancer: A Seven-Year Experience

利用机构自主研发的临床靶向测序技术提高乳腺癌患者生存率：七年经验

期刊:Cancer Research and Treatment

影响因子:3.8

doi:10.4143/crt.2024.296

Koh, Jiwon; Kim, Jinyong; Woo, Go-Un; Yi, Hanbaek; Kwon, So Yean; Seo, Jeongmin; Bae, Jeong Mo; Kim, Jung Ho; Won, Jae Kyung; Ryu, Han Suk; Jeon, Yoon Kyung; Lee, Dae-Won; Kim, Miso; Kim, Tae-Yong; Lee, Kyung-Hun; Kim, Tae-You; Lee, Jee-Soo; Seong, Moon-Woo; Kim, Sheehyun; Lee, Sungyoung; Yun, Hongseok; Song, Myung Geun; Choi, Jaeyong; Kim, Jong-Il; Im, Seock-Ah

Randomized, phase II trial to evaluate the efficacy and safety of atezolizumab plus capecitabine adjuvant therapy compared to capecitabine monotherapy for triple receptor-negative breast cancer with residual invasive cancer after neoadjuvant chemotherapy (MIRINAE trial, KCSG-BR18-21)

一项随机 II 期试验，旨在评估阿特珠单抗联合卡培他滨辅助治疗与卡培他滨单药治疗在接受新辅助化疗后仍有残留浸润性癌的三阴性乳腺癌中的疗效和安全性（MIRINAE 试验，KCSG-BR18-21）。

期刊:BMC Cancer

影响因子:3.4

doi:10.1186/s12885-025-14673-0

Lee, Jieun; Ahn, Hee Kyung; Lee, Kyung-Hun; Jung, Kyung Hae; Park, Yeon Hee; Sim, Sung Hoon; Kim, Min Hwan; Kim, Jee Hyun; Kim, Jee Hung; Lee, Kyoung Eun; Park, Kyong Hwa; Bae, Jihong; Lee, Moon Hee; Lim, Seungtaek; Kim, Han Jo; Lee, Dae-Won; Jeong, Jae Ho; Kim, Ji-Yeon; Ahn, Jin Seok; Lee, Keun Seok; Sohn, Joohyuk; Suh, Koung Jin; Cha, Yoon Jin; Shin, Kabsoo; Kim, Sung-Bae; Chae, Heejung; Kim, Gun Min; Im, Seock-Ah; Park, In Hae

Clonal Hematopoiesis and Risk of Trastuzumab-Related Cardiotoxic Effects

克隆性造血与曲妥珠单抗相关心脏毒性风险

DNA Damage and Nuclear Anaplasia Induced by Trastuzumab Deruxtecan in Cancer Cells with Variable HER2 Expression and Homologous Recombination Deficiency Status.

曲妥珠单抗德鲁替康在HER2表达和同源重组缺陷状态不同的癌细胞中诱导DNA损伤和核异型性。

Elimusertib, a Novel ATR Inhibitor, Induces Anti-tumor Effects through Replication Catastrophe in Breast Cancers.

Elimusertib 是一种新型 ATR 抑制剂，可通过乳腺癌中的复制灾难诱导抗肿瘤作用。

Nationwide real-world practice pattern and clinical data of palbociclib in HR (+), HER2 (-) metastatic breast cancer patients in Korea (KCSG BR21-15)

韩国 HR (+)、HER2 (-) 转移性乳腺癌患者使用帕博西尼治疗的全国真实世界实践模式和临床数据 (KCSG BR21-15)

Immunogenomic characteristics and prognostic implications of terminally exhausted CD8(+) T cells in colorectal cancers

结直肠癌中终末耗竭CD8(+) T细胞的免疫基因组特征及其预后意义

MSN/STAT3 drives cancer stemness and chemoresistance via IL-6/LPAR1 ligand receptor complex in triple-negative breast cancer.

MSN/STAT3 通过 IL-6/LPAR1 配体受体复合物驱动三阴性乳腺癌的干性和化疗耐药性

Establishment and characterization of 24 breast cancer cell lines and 3 breast cancer organoids reveals molecular heterogeneity and drug response variability in malignant pleural effusion-derived models.

建立和表征 24 个乳腺癌细胞系和 3 个乳腺癌类器官，揭示了恶性胸腔积液衍生模型中的分子异质性和药物反应变异性

Imaging lipid rafts reveals the principle of ApoE4-induced Aβ upregulation in human neurons

脂质筏成像揭示了 ApoE4 诱导人类神经元中 Aβ 上调的原理

Harnessing Institutionally Developed Clinical Targeted Sequencing to Improve Patient Survival in Breast Cancer: A Seven-Year Experience

利用机构自主研发的临床靶向测序技术提高乳腺癌患者生存率：七年经验

Randomized, phase II trial to evaluate the efficacy and safety of atezolizumab plus capecitabine adjuvant therapy compared to capecitabine monotherapy for triple receptor-negative breast cancer with residual invasive cancer after neoadjuvant chemotherapy (MIRINAE trial, KCSG-BR18-21)

一项随机 II 期试验，旨在评估阿特珠单抗联合卡培他滨辅助治疗与卡培他滨单药治疗在接受新辅助化疗后仍有残留浸润性癌的三阴性乳腺癌中的疗效和安全性（MIRINAE 试验，KCSG-BR18-21）。