Lee Emily M相关文献与解析，生知库 | 链接生命科学的每一步

A quantitative high-throughput screening pipeline to identify small molecule inhibitors of Chikungunya nsP2 protease

用于鉴定基孔肯雅病毒nsP2蛋白酶小分子抑制剂的定量高通量筛选流程

Li, Shuaizhang; Hu, Xin; Ahn, Yong-Mo; Medina, Angelica; Ye, Lin; Heffner, Audrey; Messing, Simon; Denson, John-Paul; Esposito, Dominic; Lee, Emily M; Martinez, Natalia J

微生物学

发表日期：2025

文献求助收藏

Discovery of SARS-CoV-2 Nsp14-Methyltransferase (MTase) Inhibitors by Harnessing Scaffold-Centric Exploration of the Ultra Large Chemical Space.

利用以骨架为中心的超大化学空间探索发现 SARS-CoV-2 Nsp14-甲基转移酶 (MTase) 抑制剂

期刊:ACS Pharmacology and Translational Science

影响因子:3.7

doi:10.1021/acsptsci.5c00111

Pal Sourav, Hanson Quinlin M, Ogden Sarah C, Lee Emily M, Martinez Natalia J, Zakharov Alexey V

Report of the Assay Guidance Workshop on 3-Dimensional Tissue Models for Antiviral Drug Development

抗病毒药物研发三维组织模型检测指导研讨会报告

期刊:Journal of Infectious Diseases

影响因子:4.5

doi:10.1093/infdis/jiad334

Jordan, Robert; Ford-Scheimer, Stephanie L; Alarcon, Rodolfo M; Atala, Anthony; Borenstein, Jeffrey T; Brimacombe, Kyle R; Cherry, Sara; Clevers, Hans; Davis, Mindy I; Funnell, Simon G P; Gehrke, Lee; Griffith, Linda G; Grossman, Abigail C; Hartung, Thomas; Ingber, Donald E; Kleinstreuer, Nicole C; Kuo, Calvin J; Lee, Emily M; Mummery, Christine L; Pickett, Thames E; Ramani, Sasirekha; Rosado-Olivieri, Edwin A; Struble, Evi B; Wan, Zhengpeng; Williams, Mark S; Hall, Matthew D; Ferrer, Marc; Markossian, Sarine

微生物学

发表日期：2023

文献求助收藏

Corrigendum to "An Integrated Systems Biology Approach Identifies the Proteasome as A Critical Host Machinery for ZIKV and DENV Replication" [Genomics Proteomics Bioinformatics19 (1) (2021) 108-122]

对“整合系统生物学方法确定蛋白酶体是寨卡病毒和登革病毒复制的关键宿主机制”的更正[基因组学、蛋白质组学、生物信息学19(1) (2021) 108-122]

期刊:Genomics Proteomics & Bioinformatics

影响因子:7.9

doi:10.1016/j.gpb.2022.12.009

Song, Guang; Lee, Emily M; Pan, Jianbo; Xu, Miao; Rho, Hee-Sool; Cheng, Yichen; Whitt, Nadia; Yang, Shu; Kouznetsova, Jennifer; Klumpp-Thomas, Carleen; Michael, Samuel G; Moore, Cedric; Yoon, Ki-Jun; Christian, Kimberly M; Simeonov, Anton; Huang, Wenwei; Xia, Menghang; Huang, Ruili; Lal-Nag, Madhu; Tang, Hengli; Zheng, Wei; Qian, Jiang; Song, Hongjun; Ming, Guo-Li; Zhu, Heng

微生物学

发表日期：2022

文献求助收藏

Integrative oncogene-dependency mapping identifies RIT1 vulnerabilities and synergies in lung cancer

整合癌基因依赖性映射揭示肺癌中 RIT1 的脆弱性和协同作用

期刊:Nature Communications

影响因子:14.7

doi:10.1038/s41467-021-24841-y

Athea Vichas #,Amanda K Riley #,Naomi T Nkinsi,Shriya Kamlapurkar,Phoebe C R Parrish,April Lo,Fujiko Duke,Jennifer Chen,Iris Fung,Jacqueline Watson,Matthew Rees,Austin M Gabel,James D Thomas,Robert K Bradley,John K Lee,Emily M Hatch,Marina K Baine,Natasha Rekhtman,Marc Ladanyi,Federica Piccioni,Alice H Berger

Application of niclosamide and analogs as small molecule inhibitors of Zika virus and SARS-CoV-2 infection

尼克酰胺及其类似物作为寨卡病毒和SARS-CoV-2感染的小分子抑制剂的应用

期刊:Bioorganic & Medicinal Chemistry Letters

影响因子:2.2

doi:10.1016/j.bmcl.2021.127906

Shamim, Khalida; Xu, Miao; Hu, Xin; Lee, Emily M; Lu, Xiao; Huang, Ruili; Shah, Pranav; Xu, Xin; Chen, Catherine Z; Shen, Min; Guo, Hui; Chen, Lu; Itkin, Zina; Eastman, Richard T; Shinn, Paul; Klumpp-Thomas, Carleen; Michael, Sam; Simeonov, Anton; Lo, Donald C; Ming, Guo-Li; Song, Hongjun; Tang, Hengli; Zheng, Wei; Huang, Wenwei

Creatine Transporter, Reduced in Colon Tissues From Patients With Inflammatory Bowel Diseases, Regulates Energy Balance in Intestinal Epithelial Cells, Epithelial Integrity, and Barrier Function

炎症性肠病患者结肠组织中肌酸转运蛋白减少，调节肠上皮细胞的能量平衡、上皮完整性和屏障功能

期刊:Gastroenterology

影响因子:25.7

doi:10.1053/j.gastro.2020.05.033

Caroline H T Hall, J Scott Lee, Emily M Murphy, Mark E Gerich, Rachael Dran, Louis E Glover, Zuhair I Abdulla, Matthew R Skelton, Sean P Colgan

Design, synthesis and discovery of andrographolide derivatives against Zika virus infection

设计、合成和发现用于对抗寨卡病毒感染的穿心莲内酯衍生物

期刊:European Journal of Medicinal Chemistry

影响因子:5.9

doi:10.1016/j.ejmech.2019.111925

Li, Feng; Lee, Emily M; Sun, Xia; Wang, Decai; Tang, Hengli; Zhou, Guo-Chun

Inhibition of zika virus infection by fused tricyclic derivatives of 1,2,4,5-tetrahydroimidazo[1,5-a]quinolin-3(3aH)-one

1,2,4,5-四氢咪唑并[1,5-a]喹啉-3(3aH)-酮的稠合三环衍生物对寨卡病毒感染的抑制作用

期刊:Bioorganic Chemistry

影响因子:4.7

doi:10.1016/j.bioorg.2020.104205

Xu, Bin; Lee, Emily M; Medina, Angelica; Sun, Xia; Wang, Decai; Tang, Hengli; Zhou, Guo-Chun

Evidence for genetically-based sperm discrimination in the vaginal tract of a primate species

灵长类动物阴道内基于基因的精子识别的证据

A quantitative high-throughput screening pipeline to identify small molecule inhibitors of Chikungunya nsP2 protease

用于鉴定基孔肯雅病毒nsP2蛋白酶小分子抑制剂的定量高通量筛选流程

Discovery of SARS-CoV-2 Nsp14-Methyltransferase (MTase) Inhibitors by Harnessing Scaffold-Centric Exploration of the Ultra Large Chemical Space.

利用以骨架为中心的超大化学空间探索发现 SARS-CoV-2 Nsp14-甲基转移酶 (MTase) 抑制剂

Report of the Assay Guidance Workshop on 3-Dimensional Tissue Models for Antiviral Drug Development

抗病毒药物研发三维组织模型检测指导研讨会报告

Corrigendum to "An Integrated Systems Biology Approach Identifies the Proteasome as A Critical Host Machinery for ZIKV and DENV Replication" [Genomics Proteomics Bioinformatics19 (1) (2021) 108-122]

对“整合系统生物学方法确定蛋白酶体是寨卡病毒和登革病毒复制的关键宿主机制”的更正[基因组学、蛋白质组学、生物信息学19(1) (2021) 108-122]

Integrative oncogene-dependency mapping identifies RIT1 vulnerabilities and synergies in lung cancer

整合癌基因依赖性映射揭示肺癌中 RIT1 的脆弱性和协同作用

Application of niclosamide and analogs as small molecule inhibitors of Zika virus and SARS-CoV-2 infection

尼克酰胺及其类似物作为寨卡病毒和SARS-CoV-2感染的小分子抑制剂的应用

Creatine Transporter, Reduced in Colon Tissues From Patients With Inflammatory Bowel Diseases, Regulates Energy Balance in Intestinal Epithelial Cells, Epithelial Integrity, and Barrier Function

炎症性肠病患者结肠组织中肌酸转运蛋白减少，调节肠上皮细胞的能量平衡、上皮完整性和屏障功能

Design, synthesis and discovery of andrographolide derivatives against Zika virus infection

设计、合成和发现用于对抗寨卡病毒感染的穿心莲内酯衍生物

Inhibition of zika virus infection by fused tricyclic derivatives of 1,2,4,5-tetrahydroimidazo[1,5-a]quinolin-3(3aH)-one

1,2,4,5-四氢咪唑并[1,5-a]喹啉-3(3aH)-酮的稠合三环衍生物对寨卡病毒感染的抑制作用