Lee Eunsook相关文献与解析，生知库 | 链接生命科学的每一步

Im, Jun-Hyung; Han, Myeonggeun; Hong, Jisu; Kim, Hyein; Oh, Kwang-Suk; Choi, Taesu; Yusoff, Abd Rashid Bin Mohd; Vasilopoulou, Maria; Lee, Eunsook; Hwang, Chan-Cuk; Noh, Yong-Young; Kim, Young-Ki

发表日期：2025

文献求助收藏

Dopaminergic REST is implicated in the tamoxifen-induced neuroprotection against manganese toxicity in female mice.

多巴胺能REST与他莫昔芬诱导的雌性小鼠抗锰中毒的神经保护作用有关。

期刊:Frontiers in Pharmacology

影响因子:4.8

doi:10.3389/fphar.2025.1627400

Pajarillo Edward, Digman Alexis, Ajayi Itunu, Kim Sanghoon, Son Deok-Soo, Aschner Michael, Lee Eunsook

Tamoxifen induces protection against manganese toxicity by REST upregulation via the ER-α/Wnt/β-catenin pathway in neuronal cells

他莫昔芬通过ER-α/Wnt/β-catenin通路上调REST表达，从而在神经元细胞中发挥抗锰毒性的保护作用。

期刊:Journal of Biological Chemistry

影响因子:3.9

doi:10.1016/j.jbc.2025.108529

Digman, Alexis; Pajarillo, Edward; Kim, Sanghoon; Ajayi, Itunu; Son, Deok-Soo; Aschner, Michael; Lee, Eunsook

Role of dopaminergic RE1-silencing transcription factor (REST) in manganese-induced behavioral deficits and dysregulating dopaminergic and serotonergic neurotransmission in mice

多巴胺能RE1沉默转录因子（REST）在锰诱导的小鼠行为缺陷和多巴胺能及血清素能神经传递失调中的作用

期刊:Neurotoxicology

影响因子:3.9

doi:10.1016/j.neuro.2025.03.001

Kim, Sanghoon; Pajarillo, Edward; Digman, Alexis; Ajayi, Itunu; Son, Deok-Soo; Aschner, Michael; Lee, Eunsook

REST

发表日期：2025

文献求助收藏

CAD (Cath. a-Differentiated) Cells Produce Dopamine along with Dopamine-Synthesizing Enzymes

CAD（Cath. a-Differentiated）细胞产生多巴胺以及多巴胺合成酶。

期刊:Neurochemical Research

影响因子:3.8

doi:10.1007/s11064-025-04474-z

Kim, Sanghoon; Pajarillo, Edward; Digman, Alexis; Ajayi, Itunu; Son, Deok-Soo; Aschner, Michael; Lee, Eunsook

细胞生物学

发表日期：2025

文献求助收藏

Tamoxifen attenuates manganese-induced dysregulation of neuronal REST via the genomic ER-Î± mechanism.

他莫昔芬通过基因组 ER-α 机制减弱锰诱导的神经元 REST 失调。

期刊:Frontiers in Molecular Neuroscience

影响因子:3.8

doi:10.3389/fnmol.2025.1648904

Digman Alexis, Pajarillo Edward, Kim Sanghoon, Ajayi Itunu, Son Deok-Soo, Aschner Michael, Lee Eunsook

Microglial Sp1 induced LRRK2 upregulation in response to manganese exposure, and 17Î²-estradiol afforded protection against this manganese toxicity.

小胶质细胞 Sp1 诱导 LRRK2 上调以应对锰暴露，而 17β-雌二醇可保护其免受锰毒性的影响

期刊:Neurotoxicology

影响因子:3.9

doi:10.1016/j.neuro.2024.05.007

Nyarko-Danquah Ivan, Pajarillo Edward, Kim Sanghoon, Digman Alexis, Multani Harpreet Kaur, Ajayi Itunu, Son Deok-Soo, Aschner Michael, Lee Eunsook

Epigenetic Mechanisms of Aluminum-Induced Neurotoxicity and Alzheimer's Disease: A Focus on Non-Coding RNAs

铝诱导神经毒性和阿尔茨海默病的表观遗传机制：聚焦非编码RNA

期刊:Neurochemical Research

影响因子:3.8

doi:10.1007/s11064-024-04214-9

Aschner, Michael; Skalny, Anatoly V; Santamaria, Abel; Rocha, Joao B T; Mansouri, Borhan; Tizabi, Yousef; Madeddu, Roberto; Lu, Rongzu; Lee, Eunsook; Tinkov, Alexey A

Retinal toxicity of heavy metals and its involvement in retinal pathology

重金属的视网膜毒性及其在视网膜病理学中的作用

期刊:Food and Chemical Toxicology

影响因子:3.5

doi:10.1016/j.fct.2024.114685

Aschner, Michael; Skalny, Anatoly V; Paoliello, Monica M B; Tinkova, Margarita N; Martins, Airton C; Santamaria, Abel; Lee, Eunsook; Rocha, Joao B T; Farsky, Sandra H P; Tinkov, Alexey A

毒理研究

发表日期：2024

文献求助收藏

Role of Astrocytes in Parkinson's Disease Associated with Genetic Mutations and Neurotoxicants

星形胶质细胞在与基因突变和神经毒物相关的帕金森病中的作用

期刊:Cells

影响因子:5.2

doi:10.3390/cells12040622

Kim, Sanghoon; Pajarillo, Edward; Nyarko-Danquah, Ivan; Aschner, Michael; Lee, Eunsook

Controlled Synthesis of Perovskite Nanocrystals at Room Temperature by Liquid Crystalline Templates

利用液晶模板在室温下可控合成钙钛矿纳米晶体

Dopaminergic REST is implicated in the tamoxifen-induced neuroprotection against manganese toxicity in female mice.

多巴胺能REST与他莫昔芬诱导的雌性小鼠抗锰中毒的神经保护作用有关。

Tamoxifen induces protection against manganese toxicity by REST upregulation via the ER-α/Wnt/β-catenin pathway in neuronal cells

他莫昔芬通过ER-α/Wnt/β-catenin通路上调REST表达，从而在神经元细胞中发挥抗锰毒性的保护作用。

Role of dopaminergic RE1-silencing transcription factor (REST) in manganese-induced behavioral deficits and dysregulating dopaminergic and serotonergic neurotransmission in mice

多巴胺能RE1沉默转录因子（REST）在锰诱导的小鼠行为缺陷和多巴胺能及血清素能神经传递失调中的作用

CAD (Cath. a-Differentiated) Cells Produce Dopamine along with Dopamine-Synthesizing Enzymes

CAD（Cath. a-Differentiated）细胞产生多巴胺以及多巴胺合成酶。

Tamoxifen attenuates manganese-induced dysregulation of neuronal REST via the genomic ER-Î± mechanism.

他莫昔芬通过基因组 ER-α 机制减弱锰诱导的神经元 REST 失调。

Microglial Sp1 induced LRRK2 upregulation in response to manganese exposure, and 17Î²-estradiol afforded protection against this manganese toxicity.

小胶质细胞 Sp1 诱导 LRRK2 上调以应对锰暴露，而 17β-雌二醇可保护其免受锰毒性的影响

Epigenetic Mechanisms of Aluminum-Induced Neurotoxicity and Alzheimer's Disease: A Focus on Non-Coding RNAs

铝诱导神经毒性和阿尔茨海默病的表观遗传机制：聚焦非编码RNA

Retinal toxicity of heavy metals and its involvement in retinal pathology

重金属的视网膜毒性及其在视网膜病理学中的作用

Role of Astrocytes in Parkinson's Disease Associated with Genetic Mutations and Neurotoxicants

星形胶质细胞在与基因突变和神经毒物相关的帕金森病中的作用