Lee Hee-Sheung相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

HSP90 inhibition disrupts telomere maintenance and promotes chromosomal instability (CIN) in cancer cells

HSP90抑制会破坏端粒维持并促进癌细胞的染色体不稳定（CIN）。

doi:10.21203/rs.3.rs-8369668/v1

Lee, Hee-Sheung; Kim, Jung-Hyun; Liskovykh, Mikhail; Len, Neckers; Kouprina, Natalay; Larionov, Vladimir

细胞生物学

发表日期：2026

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Analysis of a Novel Human Protein, ORF3, Encoded by Spacer rDNA

对一种由间隔区rDNA编码的新型人类蛋白质ORF3的分析

期刊:Journal of Molecular Evolution

影响因子:1.8

doi:10.1007/s00239-025-10269-1

Chen, Yaohui; Kim, Jung-Hyun; Lee, Hee-Sheung; Koren, Sergey; Larionov, Vladimir; Phillippy, Adam M; Schlessinger, David; Nagaraja, Ramaiah

发表日期：2025

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Variation in human chromosome 21 ribosomal RNA genes characterized by TAR cloning and long-read sequencing

利用TAR克隆和长读长测序技术表征人类21号染色体核糖体RNA基因的变异

期刊:Nucleic Acids Research

影响因子:13.1

doi:10.1093/nar/gky442

Kim, Jung-Hyun; Dilthey, Alexander T; Nagaraja, Ramaiah; Lee, Hee-Sheung; Koren, Sergey; Dudekula, Dawood; Wood Iii, William H; Piao, Yulan; Ogurtsov, Aleksey Y; Utani, Koichi; Noskov, Vladimir N; Shabalina, Svetlana A; Schlessinger, David; Phillippy, Adam M; Larionov, Vladimir

发表日期：2018

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Method to Assemble Genomic DNA Fragments or Genes on Human Artificial Chromosome with Regulated Kinetochore Using a Multi-Integrase System

利用多整合酶系统在具有调控着丝粒的人类人工染色体上组装基因组DNA片段或基因的方法

期刊:ACS Synthetic Biology

影响因子:3.9

doi:10.1021/acssynbio.7b00209

Lee, Nicholas C O; Kim, Jung-Hyun; Petrov, Nikolai S; Lee, Hee-Sheung; Masumoto, Hiroshi; Earnshaw, William C; Larionov, Vladimir; Kouprina, Natalay

发表日期：2018

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Effects of Anticancer Drugs on Chromosome Instability and New Clinical Implications for Tumor-Suppressing Therapies

抗癌药物对染色体不稳定性的影响及其对肿瘤抑制疗法的新临床意义

期刊:Cancer Research

影响因子:16.6

doi:10.1158/0008-5472.CAN-15-1617

Lee, Hee-Sheung; Lee, Nicholas C O; Kouprina, Natalay; Kim, Jung-Hyun; Kagansky, Alex; Bates, Susan; Trepel, Jane B; Pommier, Yves; Sackett, Dan; Larionov, Vladimir

发表日期：2016

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Development of a novel HAC-based "gain of signal" quantitative assay for measuring chromosome instability (CIN) in cancer cells.

开发一种基于 HAC 的新型“信号增益”定量检测方法，用于测量癌细胞中的染色体不稳定性 (CIN)

期刊:Oncotarget

doi:10.18632/oncotarget.7854

Kim Jung-Hyun, Lee Hee-Sheung, Lee Nicholas C O, Goncharov Nikolay V, Kumeiko Vadim, Masumoto Hiroshi, Earnshaw William C, Kouprina Natalay, Larionov Vladimir

细胞生物学

发表日期：2016

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Protecting a transgene expression from the HAC-based vector by different chromatin insulators

利用不同的染色质绝缘体保护转基因表达免受基于HAC的载体干扰

期刊:Cellular and Molecular Life Sciences

影响因子:6.2

doi:10.1007/s00018-013-1362-9

Lee, Nicholas C O; Kononenko, Artem V; Lee, Hee-Sheung; Tolkunova, Elena N; Liskovykh, Mikhail A; Masumoto, Hiroshi; Earnshaw, William C; Tomilin, Alexey N; Larionov, Vladimir; Kouprina, Natalay

发表日期：2013

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A new assay for measuring chromosome instability (CIN) and identification of drugs that elevate CIN in cancer cells

一种用于测量染色体不稳定性 (CIN) 并鉴定可提高癌细胞 CIN 的药物的新检测方法

期刊:BMC Cancer

影响因子:3.4

doi:10.1186/1471-2407-13-252

Lee, Hee-Sheung; Lee, Nicholas C O; Grimes, Brenda R; Samoshkin, Alexander; Kononenko, Artem V; Bansal, Ruchi; Masumoto, Hiroshi; Earnshaw, William C; Kouprina, Natalay; Larionov, Vladimir

细胞生物学

发表日期：2013

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Organization of synthetic alphoid DNA array in human artificial chromosome (HAC) with a conditional centromere

具有条件着丝粒的人类人工染色体（HAC）中合成α卫星DNA阵列的组织

期刊:ACS Synthetic Biology

影响因子:3.9

doi:10.1021/sb3000436

Kouprina, Natalay; Samoshkin, Alexander; Erliandri, Indri; Nakano, Megumi; Lee, Hee-Sheung; Fu, Haiging; Iida, Yuichi; Aladjem, Mirit; Oshimura, Mitsuo; Masumoto, Hiroshi; Earnshaw, William C; Larionov, Vladimir

发表日期：2012

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Exclusion of the 750-kb genetically unstable region at Xq27 as a candidate locus for prostate malignancy in HPCX1-linked families

排除Xq27上750 kb遗传不稳定区域作为HPCX1相关家族前列腺癌的候选基因位点

期刊:Genes Chromosomes & Cancer

影响因子:2.8

doi:10.1002/gcc.21977

Kouprina, Natalay; Lee, Nicholas C O; Pavlicek, Adam; Samoshkin, Alexander; Kim, Jung-Hyun; Lee, Hee-Sheung; Varma, Sudhir; Reinhold, William C; Otstot, John; Solomon, Greg; Davis, Sean; Meltzer, Paul S; Schleutker, Johanna; Larionov, Vladimir

发表日期：2012

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