日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Identification of a Selective Anticancer Agent from a Collection of Complex-And-Diverse Compounds Synthesized from Stevioside

从甜菊苷合成的一系列复杂多样的化合物中鉴定出一种选择性抗癌剂

Schaaf, Rachel E; Quirke, Jonathan C K; Ghavami, Maryam; Tonogai, Emily J; Lee, Hyang Yeon; Barlock, Samantha L; Trzupek, Thomas R; Abo, Kyle R; Rees, Matthew G; Ronan, Melissa M; Roth, Jennifer A; Hergenrother, Paul J

PAC-1 Synergizes with Sunitinib to Enhance Cell Death in Pancreatic Neuroendocrine Tumors

PAC-1 与舒尼替尼协同作用,增强胰腺神经内分泌肿瘤细胞的死亡

Lee, Hyang Yeon; Lee, Myung Ryul; Fan, Timothy M; Hergenrother, Paul J

A Gram-negative-selective antibiotic that spares the gut microbiome.

一种对革兰氏阴性菌具有选择性的抗生素,不会破坏肠道微生物群

Muñoz Kristen A, Ulrich Rebecca J, Vasan Archit K, Sinclair Matt, Wen Po-Chao, Holmes Jessica R, Lee Hyang Yeon, Hung Chien-Che, Fields Christopher J, Tajkhorshid Emad, Lau Gee W, Hergenrother Paul J

An Iterative Approach Guides Discovery of the FabI Inhibitor Fabimycin, a Late-Stage Antibiotic Candidate with In Vivo Efficacy against Drug-Resistant Gram-Negative Infections

迭代方法指导FabI抑制剂法比霉素的发现,法比霉素是一种后期抗生素候选药物,对耐药革兰氏阴性菌感染具有体内疗效。

Parker, Erica N; Cain, Brett N; Hajian, Behnoush; Ulrich, Rebecca J; Geddes, Emily J; Barkho, Sulyman; Lee, Hyang Yeon; Williams, John D; Raynor, Malik; Caridha, Diana; Zaino, Angela; Shekhar, Mrinal; Muñoz, Kristen A; Rzasa, Kara M; Temple, Emily R; Hunt, Diana; Jin, Xiannu; Vuong, Chau; Pannone, Kristina; Kelly, Aya M; Mulligan, Michael P; Lee, Katie K; Lau, Gee W; Hung, Deborah T; Hergenrother, Paul J

Correction to "An Iterative Approach Guides Discovery of the FabI Inhibitor Fabimycin, a Late-Stage Antibiotic Candidate with In Vivo Efficacy against Drug-Resistant Gram-Negative Infections"

对“迭代方法指导发现FabI抑制剂法比霉素,一种对耐药革兰氏阴性菌感染具有体内疗效的后期抗生素候选药物”一文的更正

Parker, Erica N; Cain, Brett N; Hajian, Behnoush; Ulrich, Rebecca J; Geddes, Emily J; Barkho, Sulyman; Lee, Hyang Yeon; Williams, John D; Raynor, Malik; Caridha, Diana; Zaino, Angela; Rohde, Jason M; Zak, Mark; Shekhar, Mrinal; Muñoz, Kristen A; Rzasa, Kara M; Temple, Emily R; Hunt, Diana; Jin, Xiannu; Vuong, Chau; Pannone, Kristina; Kelly, Aya M; Mulligan, Michael P; Lee, Katie K; Lau, Gee W; Hung, Deborah T; Hergenrother, Paul J

Pharmacokinetics and the Dermal Absorption of Bromochlorophene, a Cosmetic Preservative Ingredient, in Rats

溴氯酚(化妆品防腐剂成分)在大鼠体内的药代动力学和皮肤吸收

Yong-Jae Lee, Hyang-Yeon Kim, Quynh-Lien Pham, Jung-Dae Lee, Kyu-Bong Kim

Diverse compounds from pleuromutilin lead to a thioredoxin inhibitor and inducer of ferroptosis

侧耳素的多种化合物可作为硫氧还蛋白抑制剂和铁死亡诱导剂。

Llabani, Evijola; Hicklin, Robert W; Lee, Hyang Yeon; Motika, Stephen E; Crawford, Lisa A; Weerapana, Eranthie; Hergenrother, Paul J

Reactive Oxygen Species Synergize To Potently and Selectively Induce Cancer Cell Death

活性氧协同作用,强效且选择性地诱导癌细胞死亡

Lee, Hyang Yeon; Parkinson, Elizabeth I; Granchi, Carlotta; Paterni, Ilaria; Panigrahy, Dipak; Seth, Pankaj; Minutolo, Filippo; Hergenrother, Paul J

Metabolite Profiling Reveals the Effect of Dietary Rubus coreanus Vinegar on Ovariectomy-Induced Osteoporosis in a Rat Model

代谢物分析揭示食用红莓醋对大鼠卵巢切除术诱发的骨质疏松症的影响

Mee Youn Lee, Hyang Yeon Kim, Digar Singh, Soo Hwan Yeo, Seong Yeol Baek, Yoo Kyoung Park, Choong Hwan Lee

A Potent Inhibitor of Protein Sequestration by Expanded Triplet (CUG) Repeats that Shows Phenotypic Improvements in a Drosophila Model of Myotonic Dystrophy

一种能有效抑制扩展三联体(CUG)重复序列对蛋白质隔离的抑制剂,在果蝇强直性肌营养不良模型中显示出表型改善

Luu, Long M; Nguyen, Lien; Peng, Shaohong; Lee, JuYeon; Lee, Hyang Yeon; Wong, Chun-Ho; Hergenrother, Paul J; Chan, H Y Edwin; Zimmerman, Steven C