The benzoxathiolone LYR-71 down-regulates interferon-gamma-inducible pro-inflammatory genes by uncoupling tyrosine phosphorylation of STAT-1 in macrophages.
苯并噻唑酮 LYR-71 通过解偶联巨噬细胞中 STAT-1 的酪氨酸磷酸化来下调干扰素-γ 诱导的促炎基因
期刊:British Journal of Pharmacology
影响因子:7.7
doi:10.1111/j.1476-5381.2009.00496.x
Chung E-Y, Kim B-H, Lee I-J, Roh E, Oh S-J, Kwak J-A, Lee Y-R, Ahn B, Nam S-Y, Han S-B, Kim Y