日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A novel carboxamide bromodomain inhibitor attenuates osteoarthritis via epigenetic repression of NF-κB and MAPK signaling.

一种新型羧酰胺溴结构域抑制剂通过表观遗传抑制 NF-κB 和 MAPK 信号传导来减轻骨关节炎

Lee Hyemi, Han Seong Jae, Ok Subin, Lee Kwang Min, Choi Seungseok, Yoon Injoo, Choi Somang, Kim Jina, Ryu Serim, Son Min-Hee, Lee In-Hyun, Cho Chanmi, Yang Siyoung

A Novel BD2-Selective Inhibitor of BRDs Mitigates ROS Production and OA Pathogenesis

一种新型的BD2选择性BRD抑制剂可减轻ROS生成和OA发病机制

Lee, Hyemi; Choe, Jihye; Son, Min-Hee; Lee, In-Hyun; Lim, Min Ju; Jeon, Jimin; Yang, Siyoung

Regeneration of infarcted mouse hearts by cardiovascular tissue formed via the direct reprogramming of mouse fibroblasts

通过小鼠成纤维细胞直接重编程形成的心血管组织可再生小鼠梗塞的心脏

Jaeyeaon Cho, Sangsung Kim, Hyein Lee, Woongchan Rah, Hee Cheol Cho, Nam Kyun Kim, Seongho Bae, Dong Hoon Shin, Min Goo Lee, In-Hyun Park, Yoshiaki Tanaka, Eric Shin, Hong Yi, Ji Woong Han, Patrick Tae Joon Hwang, Ho-Wook Jun, Hun-Jun Park, Kyuwon Cho, Sang Wook Lee, Jae Kyung Jung, Rebecca D Levit,

Implantation of the clinical-grade human neural stem cell line, CTX0E03, rescues the behavioral and pathological deficits in the quinolinic acid-lesioned rodent model of Huntington's disease

植入临床级人类神经干细胞系 CTX0E03 可挽救受喹啉酸损伤的亨廷顿氏病啮齿动物模型中的行为和病理缺陷

Yongwoo Yoon, Hyun Sook Kim, Iksoo Jeon, Jeong-Eun Noh, Hyun Jung Park, Suji Lee, In-Hyun Park, Lara Stevanato, Caroline Hicks, Randolph Corteling, Roger A Barker, John D Sinden, Jihwan Song

Use of oral paclitaxel for the treatment of bladder tumors in dogs

口服紫杉醇治疗犬膀胱肿瘤

Chae, Hyung-Kyu; Yang, Ji-In; An, Ju-Hyun; Lee, In-Hyun; Son, Min-Hee; Song, Woo-Jin; Youn, Hwa-Young

DHP23002 as a next generation oral paclitaxel formulation for pancreatic cancer therapy

DHP23002 是一种用于胰腺癌治疗的新一代口服紫杉醇制剂。

Jang, Eunseo; Son, Minhee; Jang, Junhee; Lee, In-Hyun; Kim, Sol; Kwon, Taejun; Jeon, Yong-Hyun; Koh, Woo-Suk; Kim, Kil-Soo; Kim, Sang Kyoon

Nanoparticles targeting extra domain B of fibronectin-specific to the atherosclerotic lesion types III, IV, and V-enhance plaque detection and cargo delivery

靶向纤连蛋白B结构域(特异性针对动脉粥样硬化病变III、IV和V型)的纳米颗粒可增强斑块检测和药物递送。

Yu, Mikyung; Ortega, Carleena A; Si, Kevin; Molinaro, Roberto; Schoen, Frederick J; Leitao, Renata F C; Xu, Xiaoding; Mahmoudi, Morteza; Ahn, Suyeon; Liu, Jerry; Saw, Phei Er; Lee, In-Hyun; Brayner, Mirna M B; Lotfi, Azita; Shi, Jinjun; Libby, Peter; Jon, Sangyong; Farokhzad, Omid C

Modeling and correction of structural variations in patient-derived iPSCs using CRISPR/Cas9

使用 CRISPR/Cas9 对患者来源的 iPSC 中的结构变异进行建模和校正

Chul-Yong Park, Jin Jea Sung, Sang-Hwi Choi, Dongjin R Lee, In-Hyun Park, Dong-Wook Kim

A solvent-free thermosponge nanoparticle platform for efficient delivery of labile proteins

一种用于高效递送不稳定蛋白质的无溶剂热海绵纳米颗粒平台

Choi, Won Il; Kamaly, Nazila; Riol-Blanco, Lorena; Lee, In-Hyun; Wu, Jun; Swami, Archana; Vilos, Cristian; Yameen, Basit; Yu, Mikyung; Shi, Jinjun; Tabas, Ira; von Andrian, Ulrich H; Jon, Sangyong; Farokhzad, Omid C