TDP-43-induced death is associated with altered regulation of BIM and Bcl-xL and attenuated by caspase-mediated TDP-43 cleavage.

TDP-43 诱导的死亡与 BIM 和 Bcl-xL 的调节改变有关，并且可通过 caspase 介导的 TDP-43 裂解而减弱