日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Group a Streptococcus remains viable inside fibrin clots and gains access to human plasminogen for subsequent fibrinolysis and dissemination

A组链球菌在纤维蛋白凝块内仍能存活,并能接触到人纤溶酶原,进而发生纤溶和扩散。

Vu, Henry M; Moran, Thomas E; Liang, Zhong; Bao, Yun-Juan; Carles, Paulina G; Keane, Jessica C; Cerney, Madelyn G; Dahnke, Caitlyn N; Flores-Mireles, Ana L; Ploplis, Victoria A; Castellino, Francis J; Lee, Shaun W

Editorial: When streptococci seize the opportunity: identifying how manipulation of host inflammatory signaling impacts pathogenesis in streptococcal infections

社论:当链球菌抓住机会:揭示宿主炎症信号通路调控如何影响链球菌感染的发病机制

Flaherty, Rebecca A; Lee, Shaun W; Manning, Shannon D

Minimal domain peptides derived from enterocins exhibit potent antifungal activity

源自肠球菌素的最小结构域肽表现出强大的抗真菌活性

Cohen, Dorrian G; Heidenreich, Theresa M; Schorey, Jason W; Ross, Jessica N; Hammers, Daniel E; Vu, Henry M; Moran, Thomas E; Winski, Christopher J; Stuckey, Peter V; Ross, Robbi L; Yee, Elizabeth Arsenault; Santiago-Tirado, Felipe H; Lee, Shaun W

Streptolysin S targets the sodium-bicarbonate cotransporter NBCn1 to induce inflammation and cytotoxicity in human keratinocytes during Group A Streptococcal infection

链球菌溶血素S靶向钠-碳酸氢盐共转运蛋白NBCn1,在A组链球菌感染期间诱导人角质形成细胞的炎症和细胞毒性。

Hammers, Daniel E; Donahue, Deborah L; Tucker, Zachary D; Ashfeld, Brandon L; Ploplis, Victoria A; Castellino, Francis J; Lee, Shaun W

Evolution of Streptococcus pyogenes has maximized the efficiency of the Sortase A cleavage motif for cell wall transpeptidation

化脓性链球菌的进化最大限度地提高了A型分选酶切割基序对细胞壁转肽作用的效率。

Readnour, Bradley M; Ayinuola, Yetunde A; Russo, Brady T; Liang, Zhong; Lee, Shaun W; Ploplis, Victoria A; Fischetti, Vincent A; Castellino, Francis J

Rationally Designed Minimal Bioactive Domains of AS-48 Bacteriocin Homologs Possess Potent Antileishmanial Properties

合理设计的AS-48细菌素同源物的最小生物活性结构域具有强大的抗利什曼原虫活性

Corman, Hannah N; Ross, Jessica N; Fields, Francisco R; Shoue, Douglas A; McDowell, Mary Ann; Lee, Shaun W

Binding of the kringle-2 domain of human plasminogen to streptococcal PAM-type M-protein causes dissociation of PAM dimers

人纤溶酶原的kringle-2结构域与链球菌PAM型M蛋白的结合导致PAM二聚体解离。

Ayinuola, Olawole; Ayinuola, Yetunde A; Qiu, Cunjia; Lee, Shaun W; Ploplis, Victoria A; Castellino, Francis J

A Seed-Endophytic Bacillus safensis Strain With Antimicrobial Activity Has Genes for Novel Bacteriocin-Like Antimicrobial Peptides.

具有抗菌活性的种子内生芽孢杆菌菌株含有新型细菌素样抗菌肽的基因

Romero-Severson Jeanne, Moran Thomas E, Shrader Donna G, Fields Francisco R, Pandey-Joshi Susan, Thomas Clayton L, Palmer Emily C, Shrout Joshua D, Pfrender Michael E, Lee Shaun W

Group A Streptococcus-Induced Activation of Human Plasminogen Is Required for Keratinocyte Wound Retraction and Rapid Clot Dissolution

A组链球菌诱导的人纤溶酶原活化是角质形成细胞伤口回缩和血凝块快速溶解所必需的

Vu, Henry M; Hammers, Daniel E; Liang, Zhong; Nguyen, Gabrielle L; Benz, Mary E; Moran, Thomas E; Higashi, Dustin L; Park, Claudia J; Ayinuola, Yetunde A; Donahue, Deborah L; Flores-Mireles, Ana L; Ploplis, Victoria A; Castellino, Francis J; Lee, Shaun W

Novel antimicrobial peptide discovery using machine learning and biophysical selection of minimal bacteriocin domains

利用机器学习和最小细菌素结构域的生物物理筛选发现新型抗菌肽

Fields, Francisco R; Freed, Stefan D; Carothers, Katelyn E; Hamid, Md Nafiz; Hammers, Daniel E; Ross, Jessica N; Kalwajtys, Veronica R; Gonzalez, Alejandro J; Hildreth, Andrew D; Friedberg, Iddo; Lee, Shaun W