日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Decoding post-transcriptional regulatory networks by RNA-linked CRISPR screening in human cells.

利用 RNA 连接的 CRISPR 筛选技术解码人类细胞中的转录后调控网络

Nugent Patrick J, Park Heungwon, Wladyka Cynthia L, Yelland James N, Sinha Sayantani, Chen Katharine Y, Bynum Christine, Quarterman Grace, Lee Stanley C, Hsieh Andrew C, Subramaniam Arvind Rasi

TET2-loss enhances immediate and time-resolved interferon-γ signaling responses across myeloid differentiation

TET2 缺失增强了髓系分化过程中即时和时间分辨的干扰素-γ信号反应。

Jenkins, Matthew T; Chu, Yunli E; Franceski, Alana M; Potts, Chad R; Dubin, Rebecca; Dickerson, Kirsten M; Lee, Stanley C; Lu, Rui; Welner, Robert S; Ferrell, P Brent

A 30-gene classifier distinguishes low-risk MDS HSPCs from healthy HSPCs

一个包含30个基因的分类器可以区分低风险MDS造血干细胞和健康造血干细胞。

Bhat, Pawan; Van Amburg, Joseph C; Potts, Chad R; Gracie, Thomas J; Cartailler, Justin A; Parker, Alyssa C; Savona, Michael R; Lu, Rui; Lee, Stanley C; Welner, Robert S; Bick, Alexander G; Ferrell, Paul Brent

Prognostic impact of age and MDS-associated mutations in NPM1 -mutated AML

年龄和MDS相关突变对NPM1突变型急性髓系白血病预后的影响

Liu, Vivian M; Othus, Megan; Naru, Jasmine; Ries, Rhonda E; Pogosova-Agadjanyan, Era L; Appelbaum, Frederick R; Chauncey, Thomas R; Dietrich, Eliana; Erba, Harry P; Godwin, John E; Fitzgibbon, Matthew P; Fang, Min; Lee, Stanley C; Moseley, Anna; Percival, Mary-Elizabeth; Qin, Guangrong; Radich, Jerald P; Raychaudhuri, Suravi; Willman, Cheryl L; Meshinchi, Soheil; Stirewalt, Derek L

MDS-associated SF3B1 mutations promote aberrant fate choice of hematopoietic stem cell via mis-splicing of mediator kinase module component CDK8

MDS相关的SF3B1突变通过介导激酶模块组分CDK8的错误剪接促进造血干细胞的异常命运选择。

Bonner, Elizabeth A; Hsueh, Tun-Yun; Song, Axia; Arriaga-Gomez, Erica A; Venkataraman, Rasika; Sinha, Sayantani; Nguyen, Evan; Ferrell, P Brent; Welner, Robert S; Lu, Rui; Stirewalt, Derek L; Doulatov, Sergei; Lee, Stanley C

Comparing phenotypic manifolds with Kompot: Detecting differential abundance and gene expression at single-cell resolution

利用 Kompot 比较表型流形:在单细胞分辨率下检测差异丰度和基因表达

Otto, Dominik J; Arriaga-Gomez, Erica; Thieme, Elana; Yang, Ruijin; Lee, Stanley C; Setty, Manu

Verification of prognostic expression biomarkers is improved by examining enriched leukemic blasts rather than mononuclear cells from acute myeloid leukemia patients

通过检测富集的白血病原始细胞而非急性髓系白血病患者的单核细胞,可以提高预后表达生物标志物的验证效果。

Pogosova-Agadjanyan, Era L; Hua, Xing; Othus, Megan; Appelbaum, Frederick R; Chauncey, Thomas R; Erba, Harry P; Fitzgibbon, Matthew P; Jenkins, Isaac C; Fang, Min; Lee, Stanley C; Moseley, Anna; Naru, Jasmine; Radich, Jerald P; Smith, Jenny L; Willborg, Brooke E; Willman, Cheryl L; Wu, Feinan; Meshinchi, Soheil; Stirewalt, Derek L

Examining the impact of age on the prognostic value of ELN-2017 and ELN-2022 acute myeloid leukemia risk stratifications: a report from the SWOG Cancer Research Network

探讨年龄对ELN-2017和ELN-2022急性髓系白血病风险分层预后价值的影响:来自SWOG癌症研究网络的报告

Termini, Christina M; Moseley, Anna; Othus, Megan; Appelbaum, Frederick R; Chauncey, Thomas R; Erba, Harry P; Fang, Min; Lee, Stanley C; Naru, Jasmine; Pogosova-Agadjanyan, Era L; Radich, Jerald P; Willman, Cheryl L; Wu, Feinan; Meshinchi, Soheil; Stirewalt, Derek L

Mutations in spliceosome genes and therapeutic opportunities in myeloid malignancies

剪接体基因突变与髓系恶性肿瘤的治疗契机

Taylor, Justin; Lee, Stanley C

SRSF2 Mutations Contribute to Myelodysplasia by Mutant-Specific Effects on Exon Recognition

SRSF2 突变通过突变特异性影响外显子识别而导致骨髓增生异常综合征

Kim, Eunhee; Ilagan, Janine O; Liang, Yang; Daubner, Gerrit M; Lee, Stanley C-W; Ramakrishnan, Aravind; Li, Yue; Chung, Young Rock; Micol, Jean-Baptiste; Murphy, Michele E; Cho, Hana; Kim, Min-Kyung; Zebari, Ahmad S; Aumann, Shlomzion; Park, Christopher Y; Buonamici, Silvia; Smith, Peter G; Deeg, H Joachim; Lobry, Camille; Aifantis, Iannis; Modis, Yorgo; Allain, Frederic H-T; Halene, Stephanie; Bradley, Robert K; Abdel-Wahab, Omar