Antigen-IL-2 CAR-enhancer drives CAR-T fate and stemness, enhancing antitumor efficacy across models independent of IL-2Rα
抗原-IL-2 CAR增强子驱动CAR-T细胞的命运和干性，增强其在各种模型中的抗肿瘤疗效，且该作用独立于IL-2Rα。
期刊:Journal for ImmunoTherapy of Cancer
影响因子:10.6
doi:10.1136/jitc-2025-013665
Moravej, Heydar; Rakhshandehroo, Taha; Khan, Radia M M; Rivet, Victoria Marie; Marcandalli, Elodie; Mantri, Shreya R; Taklifi, Pegah; Lee, Uk-Jae; Louis, Benjamin B V; Munaretto, Leila A; Regan, Kathryn; Farkash, Zoe; Berland, Lea; Gabr, Zeina; Wolff, Alexandra N; Kowalewski, Antonia; Allen, Harris H; Nili, Ali; Baral, Jessika; Mercadante, Dayna; Fulciniti, Mariateresa; Jacobson, Caron A; Sperling, Adam S; Nadeem, Omar; Nia, Hadi T; Hemann, Michael; Munshi, Nikhil C; Rashidian, Mohammad
肿瘤
T细胞
肿瘤免疫
IL-2Rα
T细胞
IL-2
细胞生物学
免疫/内分泌
