Lee Wonhwa相关文献与解析，生知库 | 链接生命科学的每一步

Lee, Ukjin; Eun, Jung Woo; Kim, Taehee; Shim, Hyewon; Choi, Yunho; Jung, Hyeryeon; Mo, Jaewoo; Kim, Soon Sun; Baek, Geum Ok; Yoon, Moon Gyeong; Lee, Hyeyoon; Lee, Wonhwa; Kim, Wantae; Kim, Junil; Yi, Eugene C; Kim, Seung Up; Cheong, Jae Youn; Jho, Eek-Hoon

信号转导

细胞生物学

Hippo

Novel Respiratory Disease Diagnosis Tool: Development of an Au-ReS(2)-Functionalized Extended-gate Field-Effect Transistor-Type Aptasensor for Simultaneous Detection of Granzyme B and Perforin

新型呼吸系统疾病诊断工具：开发用于同时检测颗粒酶B和穿孔素的Au-ReS(2)功能化扩展栅场效应晶体管型适体传感器

期刊:Small Science

影响因子:8.3

doi:10.1002/smsc.202500485

Jung, Seokho; Ju, Minyoung; Park, Hyunjun; Kang, Sunggu; Kim, Jungbum; Seo, Yoseph; Kang, Jengmin; Jang, Jong Geol; Choi, Jung Hyun; Kim, Dong Hyung; Park, Chulhwan; Lee, Min-Ho; Lee, Wonhwa; Lee, Taek

呼吸系统疾病

发表日期：2026

文献求助收藏

cis-Clerodane-type diterpenoids from Tinospora crispa and their anticancer potential

来自皱叶青牛胆的顺式-克罗丹型二萜类化合物及其抗癌潜力

期刊:Archives of Pharmacal Research

影响因子:7.5

doi:10.1007/s12272-026-01596-y

Jeong, Se Yun; Kim, Jisun; Ha, Ji Won; Ahmad, Norhayati; Zaini, Nurul Hazlina; Ko, Yoon-Joo; Park, Alan Jung; Lee, Wonhwa; Kim, Ki Hyun

KF1601, a dual inhibitor of BCR::ABL1 and FLT3, overcomes drug resistance in FLT3(+) blast phase chronic myeloid leukemia

KF1601 是一种 BCR::ABL1 和 FLT3 的双重抑制剂，可克服 FLT3(+) 急变期慢性粒细胞白血病中的耐药性。

期刊:Molecular Cancer

影响因子:33.9

doi:10.1186/s12943-025-02292-z

Kwon, Hyun-Jin; Shin, Ji Eun; Khan, Amir; Park, So Yeon; Kim, Jiyoung; Lee, Jee-Young; Lee, Doohyun; Lee, Seungyeon; Im, Chun Young; Moon, Heegyum; Han, Ye Ri; Tamai, Minori; Akahane, Koshi; Inukai, Takeshi; Lee, Wonhwa; Kim, Hyelim; Kim, Hong Nam; Ahn, Sung-Min; Park, Hyun Woo; Kim, Dong-Wook

PRMT1Â Ablation in Endothelial Cells Causes Endothelial Dysfunction and Aggravates COPD Attributable to Dysregulated NF-ÎºB Signaling.

内皮细胞中 PRMT1 的缺失会导致内皮功能障碍，并因 NF-κB 信号传导失调而加重 COPD

期刊:Advanced Science

影响因子:14.1

doi:10.1002/advs.202411514

Tran Thi Thuy Vy, Jeong Yideul, Kim Suwoo, Yeom Ji Eun, Lee Jinwoo, Lee Wonhwa, Bae Gyu-Un, Kang Jong-Sun

Sequential nanoparticle therapy targeting neutrophil hyperactivation to prevent neutrophil-induced pulmonary fibrosis.

针对中性粒细胞过度活化的序贯纳米颗粒疗法，可预防中性粒细胞诱导的肺纤维化

期刊:Journal of Nanobiotechnology

影响因子:12.6

doi:10.1186/s12951-025-03421-y

Lee Hye-Jin, Lee Na Kyeong, Kim Jisun, Kim Jungbum, Seo Donghyuk, Shin Ha Eun, Kim Jongsu, Ahn June Hong, Kim Se-Na, Kim Hong Sook, Park Juwon, Park Wooram, Hong Kyung Soo, Park Chun Gwon, Lee Wonhwa

Engineering an immune-integrated lung-on-a-chip to reveal TOX-RAGE axis-driven fibrosis and RAGE blockade as a therapeutic strategy.

构建免疫整合的芯片肺，以揭示 TOX-RAGE 轴驱动的纤维化，并将 RAGE 阻断作为治疗策略。

期刊:Nano Convergence

影响因子:11

doi:10.1186/s40580-025-00529-7

Kim Hyelim, Park Chai Won, Kim Jisun, Kim Seong-Eun, Ahn June Hong, Seong Je Kyung, Lee Wonhwa, Cho Seung-Woo, Kim Hong Nam

Rebamipide (Mucosta®), a clinically approved drug, alleviates neuroinflammation and dopaminergic neurodegeneration in a Parkinson's disease model

瑞巴派特（Mucosta®）是一种经临床批准的药物，可减轻帕金森病模型中的神经炎症和多巴胺能神经退行性变。

期刊:Journal of Neuroinflammation

影响因子:10.1

doi:10.1186/s12974-025-03461-z

Lim, Hye-Sun; Park, Jinyoung; Kim, Eunjeong; Lee, Wonhwa; Yun, Hwi-Yeol; Lee, Seung Hoon; Park, Gunhyuk

Advanced Nanoparticle Therapeutics for Targeting Neutrophils in Inflammatory Diseases

用于靶向炎症性疾病中性粒细胞的先进纳米颗粒疗法

期刊:Advanced Healthcare Materials

影响因子:9.6

doi:10.1002/adhm.202502092

Byun, Min Ji; Nakasone, Elizabeth S; Shin, Ha Eun; Lee, Hyojin; Park, Jong-Chan; Lee, Wonhwa; Park, Wooram; Park, Chun Gwon; Park, Juwon; Kim, Se-Na

Improvement of Polymer/Metal Adhesion Using Anodizing Treatment and 3D Printing Process

利用阳极氧化处理和3D打印工艺提高聚合物/金属粘合力

期刊:Polymers

影响因子:4.9

doi:10.3390/polym17030299

Ryu, Seung Wan; Kim, Dong Hyun; Lee, Wonhwa; Hong, Jin-Yong; Jeon, Young-Pyo; Lee, Jea Uk

3D/类器官

发表日期：2025

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DKK1 Suppresses Hippo Signaling via PIP(3)-OGT-LRP6 O-GlcNAcylation in Hepatocellular Carcinoma

DKK1通过PIP(3)-OGT-LRP6 O-GlcNAc糖基化抑制肝细胞癌中的Hippo信号通路

Novel Respiratory Disease Diagnosis Tool: Development of an Au-ReS(2)-Functionalized Extended-gate Field-Effect Transistor-Type Aptasensor for Simultaneous Detection of Granzyme B and Perforin

新型呼吸系统疾病诊断工具：开发用于同时检测颗粒酶B和穿孔素的Au-ReS(2)功能化扩展栅场效应晶体管型适体传感器

cis-Clerodane-type diterpenoids from Tinospora crispa and their anticancer potential

来自皱叶青牛胆的顺式-克罗丹型二萜类化合物及其抗癌潜力

KF1601, a dual inhibitor of BCR::ABL1 and FLT3, overcomes drug resistance in FLT3(+) blast phase chronic myeloid leukemia

KF1601 是一种 BCR::ABL1 和 FLT3 的双重抑制剂，可克服 FLT3(+) 急变期慢性粒细胞白血病中的耐药性。

PRMT1Â Ablation in Endothelial Cells Causes Endothelial Dysfunction and Aggravates COPD Attributable to Dysregulated NF-ÎºB Signaling.

内皮细胞中 PRMT1 的缺失会导致内皮功能障碍，并因 NF-κB 信号传导失调而加重 COPD

Sequential nanoparticle therapy targeting neutrophil hyperactivation to prevent neutrophil-induced pulmonary fibrosis.

针对中性粒细胞过度活化的序贯纳米颗粒疗法，可预防中性粒细胞诱导的肺纤维化

Engineering an immune-integrated lung-on-a-chip to reveal TOX-RAGE axis-driven fibrosis and RAGE blockade as a therapeutic strategy.

构建免疫整合的芯片肺，以揭示 TOX-RAGE 轴驱动的纤维化，并将 RAGE 阻断作为治疗策略。

Rebamipide (Mucosta®), a clinically approved drug, alleviates neuroinflammation and dopaminergic neurodegeneration in a Parkinson's disease model

瑞巴派特（Mucosta®）是一种经临床批准的药物，可减轻帕金森病模型中的神经炎症和多巴胺能神经退行性变。

Advanced Nanoparticle Therapeutics for Targeting Neutrophils in Inflammatory Diseases

用于靶向炎症性疾病中性粒细胞的先进纳米颗粒疗法

Improvement of Polymer/Metal Adhesion Using Anodizing Treatment and 3D Printing Process

利用阳极氧化处理和3D打印工艺提高聚合物/金属粘合力