2-O, 3-O desulfated heparin (ODSH) increases bacterial clearance and attenuates lung injury in cystic fibrosis by restoring HMGB1-compromised macrophage function
2-O, 3-O 脱硫酸肝素 (ODSH) 通过恢复 HMGB1 受损的巨噬细胞功能来增加细菌清除率并减轻囊性纤维化中的肺损伤
期刊:Molecular Medicine
影响因子:6
doi:10.1186/s10020-021-00334-y
Mao Wang, Alex G Gauthier, Thomas P Kennedy, Haichao Wang, Uday Kiran Velagapudi, Tanaji T Talele, Mosi Lin, Jiaqi Wu, LeeAnne Daley, Xiaojing Yang, Vivek Patel, Sung Soo Mun, Charles R Ashby Jr, Lin L Mantell
