Leech Colin A相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

The alpha-7 nicotinic acetylcholine receptor agonist GTS-21 engages the glucagon-like peptide-1 incretin hormone axis to lower levels of blood glucose in db/db mice.

α-7 尼古丁乙酰胆碱受体激动剂 GTS-21 激活胰高血糖素样肽-1肠促胰岛素激素轴，从而降低 db/db 小鼠的血糖水平

期刊:Diabetes Obesity & Metabolism

影响因子:5.7

doi:10.1111/dom.14693

Meng Qinghe, Chepurny Oleg G, Leech Colin A, Pruekprasert Napat, Molnar Megan E, Collier James Jason, Cooney Robert N, Holz George G

发表日期：2022

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Therapeutic potential of α7 nicotinic acetylcholine receptor agonists to combat obesity, diabetes, and inflammation

α7尼古丁乙酰胆碱受体激动剂在对抗肥胖、糖尿病和炎症方面的治疗潜力

期刊:Reviews in Endocrine & Metabolic Disorders

doi:10.1007/s11154-020-09584-3

Xie, Han; Yepuri, Natesh; Meng, Qinghe; Dhawan, Ravi; Leech, Colin A; Chepurny, Oleg G; Holz, George G; Cooney, Robert N

发表日期：2020

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Nonconventional glucagon and GLP-1 receptor agonist and antagonist interplay at the GLP-1 receptor revealed in high-throughput FRET assays for cAMP

高通量 FRET 检测 cAMP 揭示了 GLP-1 受体上非常规的胰高血糖素和 GLP-1 受体激动剂和拮抗剂相互作用

期刊:Journal of Biological Chemistry

影响因子:3.9

doi:10.1074/jbc.RA118.005682

Chepurny, Oleg G; Matsoukas, Minos-Timotheos; Liapakis, George; Leech, Colin A; Milliken, Brandon T; Doyle, Robert P; Holz, George G

GPCR/Calcium/cAMP

发表日期：2019

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"A-kinase" regulator runs amok to provide a paradigm shift in cAMP signaling

“A激酶”调节因子失控，导致cAMP信号传导模式发生范式转变

期刊:Journal of Biological Chemistry

影响因子:3.9

doi:10.1074/jbc.H119.007622

Holz, George G; Chepurny, Oleg G; Leech, Colin A

GPCR/Calcium/cAMP

发表日期：2019

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Correction: Nonconventional glucagon and GLP-1 receptor agonist and antagonist interplay at the GLP-1 receptor revealed in high-throughput FRET assays for cAMP

更正：高通量 FRET 检测 cAMP 揭示了 GLP-1 受体上非常规的胰高血糖素和 GLP-1 受体激动剂和拮抗剂相互作用

期刊:Journal of Biological Chemistry

影响因子:3.9

doi:10.1074/jbc.AAC119.009193

Chepurny, Oleg G; Matsuokas, Minos-Timotheos; Liapakis, George; Leech, Colin A; Milliken, Brandon T; Doyle, Robert P; Holz, George G

GPCR/Calcium/cAMP

发表日期：2019

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Publisher Correction: Chimeric peptide EP45 as a dual agonist at GLP-1 and NPY2R receptors

出版商更正：嵌合肽EP45作为GLP-1和NPY2R受体的双重激动剂

期刊:Scientific Reports

影响因子:3.9

doi:10.1038/s41598-018-24359-2

Chepurny, Oleg G; Bonaccorso, Ron L; Leech, Colin A; Wöllert, Torsten; Langford, George M; Schwede, Frank; Roth, Christian L; Doyle, Robert P; Holz, George G

发表日期：2018

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GPR119 Agonist AS1269574 Activates TRPA1 Cation Channels to Stimulate GLP-1 Secretion.

GPR119激动剂AS1269574激活TRPA1阳离子通道以刺激GLP-1分泌

期刊:Molecular Endocrinology

doi:10.1210/me.2015-1306

Chepurny Oleg G, Holz George G, Roe Michael W, Leech Colin A

发表日期：2016

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Resveratrol Interferes with Fura-2 Intracellular Calcium Measurements.

白藜芦醇干扰Fura-2细胞内钙测量

期刊:Journal of Fluorescence

影响因子:3.1

doi:10.1007/s10895-013-1312-9

Kopp Richard F, Leech Colin A, Roe Michael W

细胞生物学

发表日期：2014

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New insights concerning the molecular basis for defective glucoregulation in soluble adenylyl cyclase knockout mice

关于可溶性腺苷酸环化酶敲除小鼠葡萄糖调节缺陷的分子基础的新见解

doi:10.1016/j.bbadis.2014.06.023

Holz, George G; Leech, Colin A; Chepurny, Oleg G

免疫/内分泌

发表日期：2014

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Synthesis, characterization and pharmacodynamics of vitamin-B(12)-conjugated glucagon-like peptide-1

维生素B12偶联胰高血糖素样肽-1的合成、表征和药效学研究

期刊:ChemMedChem

影响因子:3.4

doi:10.1002/cmdc.201200461

Clardy-James, Susan; Chepurny, Oleg G; Leech, Colin A; Holz, George G; Doyle, Robert P

发表日期：2013

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