Leeds Jennifer A相关文献与解析，生知库 | 链接生命科学的每一步

In Vitro Activity of LYS228, a Novel Monobactam Antibiotic, against Multidrug-Resistant Enterobacteriaceae

LYS228（一种新型单环β-内酰胺类抗生素）体外抗多重耐药肠杆菌科细菌的活性

期刊:Antimicrobial Agents and Chemotherapy

Blais, Johanne; Lopez, Sara; Li, Cindy; Ruzin, Alexey; Ranjitkar, Srijan; Dean, Charles R; Leeds, Jennifer A; Casarez, Anthony; Simmons, Robert L; Reck, Folkert

微生物学

发表日期：2018

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Subcellular Chemical Imaging of Antibiotics in Single Bacteria Using C(60)-Secondary Ion Mass Spectrometry

利用C(60)二次离子质谱法对单个细菌中的抗生素进行亚细胞化学成像

期刊:Analytical Chemistry

影响因子:6.7

doi:10.1021/acs.analchem.7b00466

Tian, Hua; Six, David A; Krucker, Thomas; Leeds, Jennifer A; Winograd, Nicholas

Pharmacokinetics of LFF571 and vancomycin in patients with moderate Clostridium difficile infections

LFF571 和万古霉素在中度艰难梭菌感染患者中的药代动力学

期刊:Antimicrobial Agents and Chemotherapy

影响因子:4.5

doi:10.1128/AAC.04252-14

Bhansali, Suraj G; Mullane, Kathleen; Ting, Lillian S L; Leeds, Jennifer A; Dabovic, Kristina; Praestgaard, Jens; Pertel, Peter

炎症/感染

发表日期：2015

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Multicenter, randomized clinical trial to compare the safety and efficacy of LFF571 and vancomycin for Clostridium difficile infections

一项多中心随机临床试验，旨在比较 LFF571 和万古霉素治疗艰难梭菌感染的安全性和有效性。

期刊:Antimicrobial Agents and Chemotherapy

影响因子:4.5

doi:10.1128/AAC.04251-14

Mullane, Kathleen; Lee, Christine; Bressler, Adam; Buitrago, Martha; Weiss, Karl; Dabovic, Kristina; Praestgaard, Jens; Leeds, Jennifer A; Blais, Johanne; Pertel, Peter

炎症/感染

发表日期：2015

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Subinhibitory concentrations of LFF571 reduce toxin production by Clostridium difficile

亚抑制浓度的LFF571可降低艰难梭菌的毒素产生。

期刊:Antimicrobial Agents and Chemotherapy

影响因子:4.5

doi:10.1128/AAC.04436-14

Sachdeva, Meena; Leeds, Jennifer A

发表日期：2015

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Deletion of the Î²-acetoacetyl synthase FabY in Pseudomonas aeruginosa induces hypoacylation of lipopolysaccharide and increases antimicrobial susceptibility.

铜绿假单胞菌中β-乙酰乙酰合成酶FabY的缺失会导致脂多糖酰化不足，并增加抗菌药物敏感性

期刊:Antimicrobial Agents and Chemotherapy

影响因子:4.5

doi:10.1128/AAC.01804-13

Six David A, Yuan Yanqiu, Leeds Jennifer A, Meredith Timothy C

A first-in-human, randomized, double-blind, placebo-controlled, single- and multiple-ascending oral dose study to assess the safety and tolerability of LFF571 in healthy volunteers

一项首次在人体中进行的随机、双盲、安慰剂对照、单次和多次递增口服剂量研究，旨在评估 LFF571 在健康志愿者中的安全性和耐受性。

期刊:Antimicrobial Agents and Chemotherapy

影响因子:4.5

doi:10.1128/AAC.00867-12

Ting, Lillian S L; Praestgaard, Jens; Grunenberg, Nicole; Yang, Jenny C; Leeds, Jennifer A; Pertel, Peter

发表日期：2012

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DegS and YaeL participate sequentially in the cleavage of RseA to activate the sigma(E)-dependent extracytoplasmic stress response

DegS 和 YaeL 依次参与 RseA 的切割，从而激活 σ(E) 依赖的胞外应激反应。

期刊:Genes & Development

影响因子:7.7

doi:10.1101/gad.1008902

Alba, Benjamin M; Leeds, Jennifer A; Onufryk, Christina; Lu, Chi Zen; Gross, Carol A

发表日期：2002

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When passion is not enough: the waning of the infectious disease workforce

当热情不足以应对挑战时：传染病防治队伍的衰落

In Vitro Activity of LYS228, a Novel Monobactam Antibiotic, against Multidrug-Resistant Enterobacteriaceae

LYS228（一种新型单环β-内酰胺类抗生素）体外抗多重耐药肠杆菌科细菌的活性

Subcellular Chemical Imaging of Antibiotics in Single Bacteria Using C(60)-Secondary Ion Mass Spectrometry

利用C(60)二次离子质谱法对单个细菌中的抗生素进行亚细胞化学成像

Pharmacokinetics of LFF571 and vancomycin in patients with moderate Clostridium difficile infections

LFF571 和万古霉素在中度艰难梭菌感染患者中的药代动力学

Multicenter, randomized clinical trial to compare the safety and efficacy of LFF571 and vancomycin for Clostridium difficile infections

一项多中心随机临床试验，旨在比较 LFF571 和万古霉素治疗艰难梭菌感染的安全性和有效性。

Subinhibitory concentrations of LFF571 reduce toxin production by Clostridium difficile

亚抑制浓度的LFF571可降低艰难梭菌的毒素产生。

Deletion of the Î²-acetoacetyl synthase FabY in Pseudomonas aeruginosa induces hypoacylation of lipopolysaccharide and increases antimicrobial susceptibility.

铜绿假单胞菌中β-乙酰乙酰合成酶FabY的缺失会导致脂多糖酰化不足，并增加抗菌药物敏感性

A first-in-human, randomized, double-blind, placebo-controlled, single- and multiple-ascending oral dose study to assess the safety and tolerability of LFF571 in healthy volunteers

一项首次在人体中进行的随机、双盲、安慰剂对照、单次和多次递增口服剂量研究，旨在评估 LFF571 在健康志愿者中的安全性和耐受性。

DegS and YaeL participate sequentially in the cleavage of RseA to activate the sigma(E)-dependent extracytoplasmic stress response

DegS 和 YaeL 依次参与 RseA 的切割，从而激活 σ(E) 依赖的胞外应激反应。