Increasing brain half-life of antibodies by additional binding to myelin oligodendrocyte glycoprotein, a CNS specific protein.
通过与髓鞘少突胶质细胞糖蛋白(一种中枢神经系统特异性蛋白)的额外结合,延长抗体在大脑中的半衰期
期刊:Fluids and Barriers of the Cns
影响因子:6.2
doi:10.1186/s12987-025-00624-1
Cuypers Marie-Lynn, Jaspers Tom, Clerckx Jarne, Leekens Simon, Cawthorne Christopher, Bormans Guy, Cleeren Frederik, Geukens Nick, De Strooper Bart, Dewilde Maarten