日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Affinity- and Format-Dependent Pharmacokinetics of (89)Zr-Labeled Albumin-Binding VHH Constructs

亲和力和形式依赖性的(89)Zr标记白蛋白结合VHH构建体的药代动力学

Leekens, Simon; Casteels, Peter; Van Bogaert, Tom; Deschaght, Pieter; De Brabandere, Veronique; Cawthorne, Christopher; Bormans, Guy; Cleeren, Frederik

Increasing brain half-life of antibodies by additional binding to myelin oligodendrocyte glycoprotein, a CNS specific protein.

通过与髓鞘少突胶质细胞糖蛋白(一种中枢神经系统特异性蛋白)的额外结合,延长抗体在大脑中的半衰期

Cuypers Marie-Lynn, Jaspers Tom, Clerckx Jarne, Leekens Simon, Cawthorne Christopher, Bormans Guy, Cleeren Frederik, Geukens Nick, De Strooper Bart, Dewilde Maarten

Preclinical characterization of 3p-C-DEPA(-NCS) and 3p-C-DEPA(-TFP)-PEG(4) as potential Actinium-225 bifunctional chelators using DOTA(-NCS) and macropa(-NCS) as benchmarks.

以 DOTA(-NCS) 和 macropa(-NCS) 为基准,对 3p-C-DEPA(-NCS) 和 3p-C-DEPA(-TFP)-PEG(4) 作为潜在的锕-225 双功能螯合剂进行临床前表征。

Pougoue Ketchemen Jessica, Ahenkorah Stephen, Nwangele Emmanuel, Malaza Siphelele Siphesihle Pearl, Ooms Maarten, Cardinaels Thomas, Leekens Simon, Cleeren Frederik, Fonge Humphrey

Stability profile of vimentin rod domain

波形蛋白杆状结构域的稳定性特征

Lilina, Anastasia V; Leekens, Simon; Hashim, Hani M; Vermeire, Pieter-Jan; Harvey, Jeremy N; Strelkov, Sergei V