日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Cross-modal integration of metabolomics and cardiac functionality captures dynamic metabotoxic effects of doxorubicin in engineered heart tissues

代谢组学与心脏功能跨模态整合揭示了阿霉素在工程化心脏组织中的动态代谢毒性效应

期刊:Stem Cell Reports
影响因子:5.1
doi:10.1016/j.stemcr.2025.102725
Conte, Federica; Staykova, Doroteya K; Cofiño-Fabres, Carla; Snippert, Danique; van Rooij, Arno; Lefeber, Dirk J; Passier, Robert
毒理研究
代谢
发表日期：2026
文献求助 收藏

Perioperative Management of Lithium Therapy: Considerations and Recommendations

围手术期锂疗法管理：注意事项和建议

期刊:Bipolar Disorders
影响因子:4.5
doi:10.1111/bdi.70087
Dominicus, L S; van Houwelingen, F; Marsman, M; Lefeber, G; Wilting, I; Dols, A
发表日期：2026
文献求助 收藏

Aminoadipate-semialdehyde synthase, a potential target for substrate reduction therapy in glutaric aciduria type 1

氨基己二酸半醛合酶是戊二酸尿症1型底物减少疗法的潜在靶点

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-026-44377-9
Saad, Celine; Jung-Klawitter, Sabine; Dimitrov, Bianca; Aguilar-Pimentel, Juan Antonio; Becker, Lore; da Silva-Buttkus, Patricia; Dragano, Nathalia R V; Garrett, Lillian; Hölter, Sabine M; Rathkolb, Birgit; Sanz-Moreno, Adrián; Spielmann, Nadine; Fuchs, Helmut; Gailus-Durner, Valerie; Schaaf, Christian P; la Marca, Giancarlo; Damiano, Roberta; Lefeber, Dirk J; Engelke, Udo; de Angelis, Martin Hrabe; Houten, Sander M; Kölker, Stefan
发表日期：2026
文献求助 收藏

Untargeted Metabolomics for Diagnosis, Monitoring, and Understanding the Pathophysiology of Inherited Metabolic Disorders

非靶向代谢组学在遗传性代谢疾病的诊断、监测和病理生理学研究中的应用

期刊:Journal of Inherited Metabolic Disease
影响因子:3.8
doi:10.1002/jimd.70120
Martens, Jonathan; Engelke, Udo F H; Wevers, Ron A; Lefeber, Dirk J; Kulkarni, Purva
代谢
发表日期：2026
文献求助 收藏

Investigating the utilization mechanism and kinetics of sialic acid mimetics in mammalian cell lines

研究唾液酸模拟物在哺乳动物细胞系中的利用机制和动力学

期刊:RSC Chemical Biology
影响因子:3.1
doi:10.1039/d5cb00193e
Visser, Eline A; Hornikx, Daniël L A H; Rahm, Moritz; Öztürk, Özden; Psomiadou, Venetia; Calzari, Matteo; Mennen, Celine; Moons, Sam J; Jaeger, Martin; Lefeber, Dirk J; Büll, Christian; Boltje, Thomas J
细胞生物学
发表日期：2026
文献求助 收藏

Imaging flow cytometry-based cellular screening elucidates pathophysiology in individuals with Variants of Uncertain Significance

基于成像流式细胞术的细胞筛查阐明了具有意义未明变异的个体的病理生理学

期刊:Genome Medicine
影响因子:11.2
doi:10.1186/s13073-025-01433-9
Muffels, Irena Josephina Johanna; Waterham, Hans R; D'Alessandro, Giuseppina; Zagnoli-Vieira, Guido; Sacher, Michael; Lefeber, Dirk J; Van der Vinne, Celine; Roifman, Chaim M; Gassen, Koen L I; Rehmann, Holger; Van Haaften-Visser, Desiree Y; Nieuwenhuis, Edward S S; Jackson, Stephen P; Fuchs, Sabine A; Wijk, Femke; van Hasselt, Peter
细胞生物学
FCM
发表日期：2025
文献求助 收藏

Structure Elucidation for MALDI Mass Spectrometry Imaging Using Infrared Ion Spectroscopy

利用红外离子光谱进行MALDI质谱成像的结构解析

期刊:Analytical Chemistry
影响因子:6.7
doi:10.1021/acs.analchem.5c00948
Schuurman, Jelle L; van Tetering, Lara; Houthuijs, Kas J; Kooijman, Pieter; Gailus-Durner, Valerie; Leuchtenberger, Stefanie; Fuchs, Helmut; Hrabe de Angelis, Martin; Engelke, Udo F H; Lefeber, Dirk J; van Karnebeek, Clara D M; Wevers, Ron A; Grgic, Andrej; Balluf, Benjamin; Vandenbosch, Michiel; Vreeken, Rob; Heeren, Ron M A; Berden, Giel; Oomens, Jos; Martens, Jonathan
发表日期：2025
文献求助 收藏

SLC10A7 regulates O-GalNAc glycosylation and Ca2+ homeostasis in the secretory pathway: insights into SLC10A7-CDG

SLC10A7 调节分泌途径中的 O-GalNAc 糖基化和 Ca2+ 稳态：对 SLC10A7-CDG 的见解

期刊:Cellular and Molecular Life Sciences
影响因子:6.2
doi:10.1007/s00018-024-05551-2
Zoé Durin, Aurore Layotte, Willy Morelle, Marine Houdou, Antoine Folcher, Dominique Legrand, Dirk Lefeber, Natalia Prevarskaya, Julia Von Blume, Valérie Cormier-Daire, François Foulquier
Human
GM130
发表日期：2025
文献求助 收藏

Targeting AASS alleviates neurotoxicity and improves mitochondrial function in astrocyte models for pyridoxine-dependent epilepsy.

靶向 AASS 可减轻神经毒性，并改善吡哆醇依赖性癫痫星形胶质细胞模型中的线粒体功能。

期刊:Molecular Therapy-Nucleic Acids
影响因子:6.1
doi:10.1016/j.omtn.2025.102728
Schuurmans Imke M E, Engelke Udo, Abedrabbo Muna, Puvogel Sofía, Mijdam Rachel, Scholten Gijs-Jan, van Katwijk Sara B, Oudakker Astrid, Al-Shekaili Hilal H, Lefeber Dirk J, Leavitt Blair R, van Karnebeek Clara D M, Nadif Kasri Nael, Garanto Alejandro
癫痫
细胞生物学
神经科学
胶质细胞
线粒体
发表日期：2025
文献求助 收藏

Glycoproteomics analysis of complement factor H and its complement-regulatory function during Streptococcus pneumoniae-associated hemolytic uremic syndrome

链球菌相关溶血性尿毒综合征中补体因子H及其补体调节功能的糖蛋白组学分析

期刊:Frontiers in Immunology
影响因子:5.9
doi:10.3389/fimmu.2025.1645196
Baas, Laura M; Wijnsma, Kioa L; Zijlstra, Fokje; van de Kar, Nicole C A J; Ter Steeg, Lieke; Bouts, Antonia H M; Michels, Marloes A H M; Langereis, Jeroen D; Lefeber, Dirk; Wessels, Hans J C T; van den Heuvel, Lambertus P
免疫/内分泌
发表日期：2025
文献求助 收藏