Lefkovith相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

An esophagus cell atlas reveals dynamic rewiring during active eosinophilic esophagitis and remission

食管细胞图谱揭示活动性嗜酸性食管炎和缓解期间的动态重新布线

期刊:Nature Communications

影响因子:14.7

doi:10.1038/s41467-024-47647-0

Jiarui Ding #, John J Garber #, Amiko Uchida, Ariel Lefkovith, Grace T Carter, Praveen Vimalathas, Lauren Canha, Michael Dougan, Kyle Staller, Joseph Yarze, Toni M Delorey, Orit Rozenblatt-Rosen, Orr Ashenberg, Daniel B Graham, Jacques Deguine, Aviv Regev, Ramnik J Xavier

细胞生物学

发表日期：2024

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The landscape of immune dysregulation in Crohn's disease revealed through single-cell transcriptomic profiling in the ileum and colon

通过回肠和结肠单细胞转录组分析揭示克罗恩病的免疫失调状况

期刊:Immunity

影响因子:25.5

doi:10.1016/j.immuni.2023.01.002

Lingjia Kong, Vladislav Pokatayev, Ariel Lefkovith, Grace T Carter, Elizabeth A Creasey, Chirag Krishna, Sathish Subramanian, Bharati Kochar, Orr Ashenberg, Helena Lau, Ashwin N Ananthakrishnan, Daniel B Graham, Jacques Deguine, Ramnik J Xavier

细胞生物学

发表日期：2023

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Genetic vulnerability to Crohn's disease reveals a spatially resolved epithelial restitution program

克罗恩病遗传易感性揭示了一种空间分辨的上皮修复程序

期刊:Science Translational Medicine

影响因子:14.6

doi:10.1126/scitranslmed.adg5252

Nakata, Toru; Li, Chenhao; Mayassi, Toufic; Lin, Helen; Ghosh, Koushik; Segerstolpe, Åsa; Diamond, Emma L; Herbst, Paula; Biancalani, Tommaso; Gaddam, Shreya; Parkar, Saurabh; Lu, Ziqing; Jaiswal, Alok; Li, Bihua; Creasey, Elizabeth A; Lefkovith, Ariel; Daly, Mark J; Graham, Daniel B; Xavier, Ramnik J

发表日期：2023

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Remodeling of colon plasma cell repertoire within ulcerative colitis patients

溃疡性结肠炎患者结肠浆细胞库的重塑

期刊:Journal of Experimental Medicine

影响因子:12.6

doi:10.1084/jem.20220538

Johannes F Scheid #, Basak Eraslan #, Andrew Hudak, Eric M Brown, Dallis Sergio, Toni M Delorey, Devan Phillips, Ariel Lefkovith, Alison T Jess, Lennard W Duck, Charles O Elson, Hera Vlamakis, Damian R Plichta, Jacques Deguine, Ashwin N Ananthakrishnan, Daniel B Graham, Aviv Regev, Ramnik J Xavier

细胞生物学

发表日期：2023

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QRICH1 dictates the outcome of ER stress through transcriptional control of proteostasis

QRICH1 通过转录调控蛋白质稳态来决定内质网应激的结果

影响因子:44.7

doi:10.1126/science.abb6896

Kwontae You, Lingfei Wang, Chih-Hung Chou, Kai Liu, Toru Nakata, Alok Jaiswal, Junmei Yao, Ariel Lefkovith, Abdifatah Omar, Jacqueline G Perrigoue, Jennifer E Towne, Aviv Regev, Daniel B Graham, Ramnik J Xavier

发表日期：2021

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Single-cell transcriptomic profiles reveal changes associated with BCG-induced trained immunity and protective effects in circulating monocytes

单细胞转录组分析揭示了与卡介苗诱导的训练免疫和循环单核细胞的保护作用相关的变化

期刊:Cell Reports

影响因子:6.9

doi:10.1016/j.celrep.2021.110028

Kong, Lingjia; Moorlag, Simone J C F M; Lefkovith, Ariel; Li, Bihua; Matzaraki, Vasiliki; van Emst, Liesbeth; Kang, Heather A; Latorre, Isabel; Jaeger, Martin; Joosten, Leo A B; Netea, Mihai G; Xavier, Ramnik J

细胞生物学

免疫/内分泌

发表日期：2021

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Cell Type- and Stimulation-Dependent Transcriptional Programs Regulated by Atg16L1 and Its Crohn's Disease Risk Variant T300A

Atg16L1 及其克罗恩病风险变体 T300A 调控的细胞类型和刺激依赖性转录程序

期刊:Journal of Immunology

影响因子:3.6

doi:10.4049/jimmunol.1900750

Mukund Varma, Motohiko Kadoki, Ariel Lefkovith, Kara L Conway, Kevin Gao, Vishnu Mohanan, Betsabeh Khoramian Tusi, Daniel B Graham, Isabel J Latorre, Andrew C Tolonen, Bernard Khor, Aylwin Ng, Ramnik J Xavier

细胞生物学

发表日期：2020

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SLC45A2 protein stability and regulation of melanosome pH determine melanocyte pigmentation

SLC45A2蛋白的稳定性和黑素体pH值的调节决定了黑素细胞的色素沉着。

期刊:Molecular Biology of the Cell

影响因子:3.1

doi:10.1091/mbc.E20-03-0200

Linh Le ，Iliana E Escobar ，Tina Ho ，Ariel J Lefkovith ，Emily Latteri ，Kirk D Haltaufderhyde ，Megan K Dennis ，Lynn Plowright ，Elena V Sviderskaya ，Dorothy C Bennett ，Elena Oancea ，Michael S Marks

细胞生物学

发表日期：2020

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A missense variant in SLC39A8 confers risk for Crohn's disease by disrupting manganese homeostasis and intestinal barrier integrity

SLC39A8 的错义变异会破坏锰稳态和肠道屏障完整性，从而增加患克罗恩病的风险

期刊:Proceedings of the National Academy of Sciences of the United States of America

doi:10.1073/pnas.2014742117

Toru Nakata, Elizabeth A Creasey, Motohiko Kadoki, Helen Lin, Martin K Selig, Junmei Yao, Ariel Lefkovith, Mark J Daly, Daniel B Graham, Ramnik J Xavier

发表日期：2020

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Transcriptional Atlas of Intestinal Immune Cells Reveals that Neuropeptide α-CGRP Modulates Group 2 Innate Lymphoid Cell Responses

肠道免疫细胞转录图谱揭示神经肽 α-CGRP 调节第 2 组先天淋巴细胞反应

期刊:Immunity

影响因子:25.5

doi:10.1016/j.immuni.2019.09.004

Heping Xu, Jiarui Ding, Caroline B M Porter, Antonia Wallrapp, Marcin Tabaka, Sai Ma, Shujie Fu, Xuanxuan Guo, Samantha J Riesenfeld, Chienwen Su, Danielle Dionne, Lan T Nguyen, Ariel Lefkovith, Orr Ashenberg, Patrick R Burkett, Hai Ning Shi, Orit Rozenblatt-Rosen, Daniel B Graham, Vijay K Kuchroo,

发表日期：2019

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