日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Nonlinear Mixed-Effects Modeling to Characterize the Pharmacokinetics of a Novel Mithramycin Analogue for Ewing Sarcoma in Mice

利用非线性混合效应模型表征新型米索霉素类似物治疗小鼠尤文氏肉瘤的药代动力学

期刊:
影响因子:
doi:10.21203/rs.3.rs-9035594/v1
Niloy, Kumar Kulldeep; Horn, Jamie; Bhuiyan, Nazmul Hasan; Shaaban, Khaled A; Bhosale, Suhas S; Prisinzano, Thomas; Thorson, Jon S; Rohr, Jurgen; Leggas, Markos
发表日期：2026
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Age-adjusted dosing of fludarabine for lymphodepletion in CAR T-cell therapy: a clinical trial simulation study

CAR-T细胞疗法中用于淋巴清除的氟达拉滨年龄调整剂量：一项临床试验模拟研究

期刊:Blood Advances
影响因子:7.1
doi:10.1182/bloodadvances.2025015928
Panetta, John C; Talleur, Aimee C; Naik, Swati; Gottschalk, Stephen; Leggas, Markos
细胞生物学
T细胞
T细胞
免疫/内分泌
发表日期：2025
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Pharmacokinetic Modeling and Model-Based Hypothesis Generation for Dose Optimization of Clonidine in Neonates With Neonatal Opioid Withdrawal Syndrome

新生儿阿片类药物戒断综合征中可乐定剂量优化的药代动力学建模和基于模型的假设生成

期刊:Clinical Pharmacology & Therapeutics
影响因子:5.5
doi:10.1002/cpt.3507
Tang, Fei; Ng, Chee M; Horn, Jamie; Bada, Henrietta S; Leggas, Markos
发表日期：2025
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Preclinical Pharmacokinetic Evaluation of Mithramycin and Mithramycin SA Tryptophan-Conjugated Analog

米索霉素及其色氨酸偶联类似物的临床前药代动力学评价

期刊:Pharmaceutics
影响因子:5.5
doi:10.3390/pharmaceutics17060765
Niloy, Kumar Kulldeep; Horn, Jamie; Bhuiyan, Nazmul H; Shaaban, Khaled A; Bhosale, Suhas S; Prisinzano, Thomas E; Thorson, Jon S; Rohr, Jurgen; Leggas, Markos
发表日期：2025
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The Position of Indole Methylation Controls the Structure, DNA Binding, and Cellular Functions of Mithramycin SA-Trp Analogues.

吲哚甲基化的位置控制着米索霉素 SA-Trp 类似物的结构、DNA 结合和细胞功能

期刊:Chembiochem
影响因子:2.8
doi:10.1002/cbic.202401084
Hou Caixia, Bhosale Suhas, Yasuda Kazuto, Yetirajam Rajesh, Leggas Markos, Rohr Jürgen, Tsodikov Oleg V
细胞生物学
DNA甲基化
DNA甲基化
发表日期：2025
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Clonidine as Monotherapy for Neonatal Opioid Withdrawal Syndrome: A Randomized Trial

可乐定单药治疗新生儿阿片类药物戒断综合征：一项随机试验

期刊:Pediatrics
影响因子:6.4
doi:10.1542/peds.2023-065610
Bada, Henrietta S; Westgate, Philip M; Sithisarn, Thitinart; Yolton, Kimberly; Charnigo, Richard; Pourcyrous, Massroor; Tang, Fei; Gibson, Julia; Shearer-Miller, Jennifer; Giannone, Peter; Leggas, Markos
发表日期：2024
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Neonatal Abstinence Signs during Treatment: Trajectory, Resurgence and Heterogeneity

治疗期间新生儿戒断迹象：轨迹、复发和异质性

期刊:Children-Basel
影响因子:2.1
doi:10.3390/children11020203
Miller, Jennifer S; Bada, Henrietta S; Westgate, Philip M; Sithisarn, Thitinart; Leggas, Markos
发表日期：2024
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Clinical pharmacology and dosing regimen optimization of neonatal opioid withdrawal syndrome treatments

新生儿阿片类药物戒断综合征治疗的临床药理学和给药方案优化

期刊:Cts-Clinical and Translational Science
影响因子:2.8
doi:10.1111/cts.12994
Tang, Fei; Ng, Chee M; Bada, Henrietta S; Leggas, Markos
发表日期：2021
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OleD Loki as a Catalyst for Hydroxamate Glycosylation

OleD Loki 作为羟肟酸糖基化的催化剂

期刊:Chembiochem
影响因子:2.8
doi:10.1002/cbic.201900601
Hughes, Ryan R; Shaaban, Khaled A; Ponomareva, Larissa V; Horn, Jamie; Zhang, Chunhui; Zhan, Chang-Guo; Voss, S Randal; Leggas, Markos; Thorson, Jon S
发表日期：2020
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Population pharmacokinetic analysis of AR-67, a lactone stable camptothecin analogue, in cancer patients with solid tumors

AR-67（一种内酯稳定的喜树碱类似物）在实体瘤癌症患者中的群体药代动力学分析

期刊:Investigational New Drugs
影响因子:2.7
doi:10.1007/s10637-019-00744-0
Tang, Fei; Tsakalozou, Eleftheria; Arnold, Susanne M; Ng, Chee M; Leggas, Markos
肿瘤
肿瘤免疫
发表日期：2019
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